A Pharmaceutical Executive on Trump’s Tariff Strategy

Speaker 1 At a cabinet meeting earlier this month, President Trump made an announcement for the pharmaceutical industry.

Speaker 2 We're going to give people about a year, a year and a half to come in, and after that, they're going to be tariffed.

Speaker 2 If they have to bring the pharmaceuticals into the country, the drugs and other things into the country, they're going to be tariffed at a very, very high rate, like 200%.

Speaker 2 We'll give them a certain period.

Speaker 1 Like Trump's tariffs on other industries, a primary goal is to encourage manufacturers to move their operations into the U.S.

Speaker 1 And already, some of the largest pharma companies in the world are responding. AstraZeneca is expanding its manufacturing capability here in the U.S.

Speaker 1 The UK-based company just announcing a $50 billion expansion.

Speaker 3 Drugs giant Roche said Tuesday it would invest $50 billion in the U.S. over the next five years.

Speaker 4 Here in this country, it's a $27 billion investment for Eli Lilly and company. It's the maker.

Speaker 1 But drug makers from one sector of the industry say that manufacturing in the U.S. isn't really an option for them.

Speaker 1 I spoke to the CEO of one of those companies.

Speaker 5 I'm Richard Saino. I'm the CEO of a company called Sandos.

Speaker 1 And it is Sandos or Sando? I feel like I've heard.

Speaker 5 People say both.

Speaker 5 Yeah.

Speaker 1 Sandos is a Switzerland-based company, and it's one of the world's largest makers of generic drugs.

Speaker 1 Generics are medicines whose patents have expired and can be made by many drug companies, and they generally cost less than brand name drugs.

Speaker 1 Richard has been in talks with the U.S. government, and he says tariffs aren't the way to encourage companies like his to invest in U.S.
manufacturing.

Speaker 1 You're working with the Trump administration and having conversations with them, but you've also spoken publicly about your concerns over these tariffs when it comes to your business, to generics.

Speaker 1 Why is that? What are you hoping to achieve by speaking out about this?

Speaker 5 This industry treats most of the patients most of the time in the U.S. for a fraction of the cost.
These are low-cost products, frequently sold in pennies on the dollar.

Speaker 5 And so tariffs have a huge disproportionate impact.

Speaker 1 Welcome to The Journal, our show about money, business, and power. I'm Jessica Mendoza.
It's Monday, July 28th.

Speaker 1 Coming up on the show, a pharma executive on Trump's tariff strategy and what it means for generic drugs.

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Speaker 1 Generic drug makers like Sando's have a different business model than brand name drug makers. Here's the company's CEO, Richard Sayner, again.

Speaker 5 Mostly when they think of pharmaceuticals, they think this is one industry, but really in simple terms, there's two industries.

Speaker 5 There's the patented industry that, I guess, innovates, brings new drugs to the market. Generally, there's a sold at very high prices.

Speaker 1 So think about a patented brand name drug, like Prozac.

Speaker 5 Prozac Weekly is here.

Speaker 4 Ask your doctor if it's right for you. You can learn more about it.

Speaker 1 Pharma giant Eli Lilly, which developed the drug, held the patent on it for more than a decade. During that time, Lilly was the only company that could sell the drug, making it billions of dollars.

Speaker 1 When Prozac's patent expired in the early 2000s, that opened the door for other manufacturers to make the generic version, which is called fluexetine.

Speaker 1 Richards' company Sandos has made one. In fact, 90% of prescription drugs in America are generics made by companies like Sando's.

Speaker 5 My job, in a sense, or my company's job, is to bring copies of those drugs to the market as quickly as possible and really drive down costs.

Speaker 5 So to give you an example, in the U.S., about 90% of all of the drugs dispensed are generics and biosimilars, but they only cost to U.S. patients about 13% of the total drugs bills.

Speaker 5 So by far the biggest part of the user, but by far the smaller part in terms of the cost.

Speaker 1 Because generics are often much less expensive, the profit margins for the industry are smaller. And so tariffs, especially a possible 200% tariff like the one Trump proposed, they hit harder.

Speaker 1 Those smaller profit margins also make it harder to manufacture in America, where costs are higher. Most of Sando's manufacturing facilities are in Europe, with some factories in India and Brazil.

Speaker 1 What would your margins look like if you did try to bring manufacturing into the U.S.? What would the experience be like for your company to try and do that?

Speaker 5 Today, it would be loss-making.

Speaker 5 Because if I'm selling a pack of antibiotics, for me to build a new beta-lactam facility, a penicillin facility, that's about $2 to $3 billion.

Speaker 5 Now, the board would never give me $2 to $3 billion, but I mean, assuming I convinced the board. So where's the market?

Speaker 5 We currently sell a packet of antibiotics to the U.S. at a price less than a packet of M ⁇ Ms.

Speaker 5 And we lose money doing that. And then we get a 200% tariff on that.

Speaker 5 Now, if I genuinely believe there was an opportunity to sell antibiotics and build a factory and get rewarded for that investment, of course, I'm a businessman. We'd make that investment.

Speaker 1 Richard told investors in an earnings call that the company would be able to absorb the costs of the tariffs without passing the price on to consumers.

Speaker 5 Anything beyond that, then we will disclose when we get to our next earnings call.

Speaker 1 What would your options be?

Speaker 5 Well, I guess you have two or three. In the short term, if we consistently don't make money, we'd look at then raising prices.

Speaker 5 And if we can't raise prices, then we would probably withdraw the product from the market.

Speaker 1 What effect do you think that would have on US consumers if you had to do that?

Speaker 5 So we have a record of making sure we put patients first and making sure that we're sustainable in the market.

Speaker 5 Honestly, we'd have to look at it case by case. I mean, we have a moral responsibility to make sure patients have access to medicine, which takes precedence over everything else.

Speaker 5 But we also have a business to run.

Speaker 5 You know, and clearly over time, if we can't pass on price increases through whatever mechanisms and there are other competitors who have either for whatever reason lower price products or want to go into that market then we'd look at them a case by case and there's no world in which you would move manufacturing to the user well there is clearly a world where i would but it's not the tariffs alone it's also a combination of structural reform to show that there's a way that i can make a sustainable return in the us

Speaker 5 and i know that's what the administrator they want u.s products made in the u.s that are affordable and sustainable. I want exactly the same things.

Speaker 5 But the trouble is a tariff is a relatively simplistic tool that tries to address many problems through one action.

Speaker 1 Richard says that what the tariffs are doing for the generics industry is open up a broader conversation about structural reforms.

Speaker 5 All credit. to this administration.
I mean, we've had better access to this administration at various levels as an industry and as a company. I mean, I was in Washington a few weeks ago.

Speaker 5 So I think we have good access. And I think really we want the same things.
I want to make sure that American patients can get affordable, high-quality medicines available in their marketplace.

Speaker 5 I think tariffs are a mechanism to force that conversation.

Speaker 5 So I think the positives out of it, look, it's forcing us to think about what would it take for us to invest in the US and how do we make the US a sustainable market? Tariffs is part of the equation.

Speaker 5 The bigger question is, how do we make this a market that makes, warrants, sustainable investment? How do we understand the patent landscape? How do we understand the payer framework?

Speaker 5 How do we make sure there's fair competition?

Speaker 1 What Richard says needs to change for generic drugs in the US?

Speaker 1 That's next.

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Speaker 1 Sandos has built a steady business in the U.S. selling all kinds of generics and biosimilars.
Biosimilars are copies of medicines derived from living organisms or their components.

Speaker 1 And even though the U.S. is one of Sandos' biggest markets, Richard says it's not a very easy one.

Speaker 1 How would you describe the U.S. market compared to others that you operate in around the world?

Speaker 5 I mean, in one word, unpredictable.

Speaker 5 Now, I know in Europe and the most regulated markets when the patent will expire, and I know how the market will evolve and in many markets actually there's legislation to encourage the use of generics and biosimilars over the originator.

Speaker 5 The trouble is in the US every time I launch a product I have to go to court and you know if you go to court sometimes you win sometimes you lose so there's an uncertainty there.

Speaker 1 In Richard's view US law is deferential to patent holders. And he says his company often faces pushback when trying to introduce a generic drug in the US.

Speaker 5 The originators continue to find mechanisms to extend patents. So let me give you a good example.
A drug like Embroil.

Speaker 5 Embroil has been freely available in Europe for the last five years.

Speaker 1 Embroil is a brand name drug manufactured by the company Amgen. It reduces inflammation and is used to treat arthritis and other autoimmune conditions.

Speaker 1 Richards' company sells a biosimilar version of this in Europe, but can't sell it in the US.

Speaker 5 Because of how Amgen chose to use US patent law, it's effectively created a 30-year monopoly. Now, I can't launch this product in the US.

Speaker 5 We're currently in litigation with Amgen to challenge that decision because we believe patients should have access to a biologic probably 12 to 15 years after the drug is first launched, certainly not 30 years.

Speaker 5 So, then you put all of those things together in the US means that this is probably one of the most uncertain markets in the world.

Speaker 1 A spokesperson spokesperson for Amgen said that the company doesn't comment on pending litigation.

Speaker 1 Another problem, according to Richard, are the middlemen in the healthcare industry.

Speaker 1 These middlemen act as drug price negotiators, and they've driven down the prices of what they pay for generics in the US.

Speaker 5 The middlemen have generally consolidated. So you now have a situation that really, the US really has only three big customers who are buying generic drugs.

Speaker 5 Now, if you've got 10 suppliers selling into three customers, what happens? Pricing goes down. It's just simple economics.

Speaker 1 Today, generic makers have a net profit margin of 18% in the U.S. compared with 28% for brand name drug makers.

Speaker 1 That's according to research by the University of Southern California's Schaefer Institute.

Speaker 5 You're basically competing purely on price, and that makes it very difficult. So tariffs alone need to be then brought in combination of how we understand and change the dynamics of the marketplace.

Speaker 1 It's this tricky U.S. market that Trump's pharma tariffs would trickle into.

Speaker 1 Richard says he's keeping the lines of communication open with the administration and he's hopeful that Sando's can continue to grow in the US.

Speaker 5 I think the positive to me is at least we're having the right conversations. I think behind the scenes they understand all of these issues.

Speaker 5 You know, this is still the most attractive market in the world. And I'd love to bring more products to more American patients.
And I'd love to build factories in the US.

Speaker 5 But I need to be confident that I'm going to get a return on that investment.

Speaker 1 So it sounds like you're optimistic about how these conversations are going.

Speaker 5 Look, I think, put it this way, it can't get much worse from where we started.

Speaker 5 And so,

Speaker 5 and I think this administration recognizes that something needs to change.

Speaker 1 From where things stand right now, what does Sandos' future in the U.S. market look like? Do you feel like it's going to grow here or are you going to be focusing your efforts elsewhere?

Speaker 5 Look, I absolutely have no doubt our U.S. business will continue to grow.

Speaker 5 You know, we've always had a business in the US. We will continue to have a business in the US.
And clearly, I'd love to invest in the U.S.

Speaker 5 But we will see. And America, the U.S.
is an exciting market.

Speaker 5 But equally, I want to work with an administration and with the regulators to find ways to bring more products more sustainably to warrant that investment.

Speaker 5 Where's the incentives to invest, to go to court, to build factories, to take risks? And those are really the conversation we're trying to have.

Speaker 1 Yesterday, the U.S. said it reached a trade deal with the European Union.
The agreement includes a baseline tariff rate of 15% on most goods coming from the EU.

Speaker 1 But as of now, there's uncertainty as to whether or not that rate will apply to European-made pharmaceuticals.

Speaker 1 So tariffs or no tariffs, whatever happens with this policy. It's really this, is the U.S.
going to be able to make these structural changes?

Speaker 5 It's the structural nature of the market that needs to evolve. So this isn't really a tariff conversation.

Speaker 5 This is a market conversation. So in a sense, tariffs is a bit of a smokescreen.
This is about how do we change the nature of the U.S. market to the benefit of U.S.
patients.

Speaker 5 But look, I'm very proud about what we do. I'm really excited about our future.
And look, the U.S.

Speaker 5 is an important place and I'd love to find ways to invest and expand our business here and continue to serve American patients.

Speaker 1 Well, Richard Sayner, CEO of Sandos, thank you so much for your time.

Speaker 5 Pleasure. Thank you so much.

Speaker 1 That's all for today, Monday, July 28th. The journal is a co-production of Spotify and the Wall Street Journal.
Additional reporting in this episode by Jared Hopkins, Kim McCraille, and David Wayner.

Speaker 1 Special thanks to Peter Loftus.

Speaker 1 Thanks for listening. See you tomorrow.