Sawbones: Sex Chocolate
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Transcript
Sawbones is a show about medical history, and nothing the hosts say should be taken as medical advice or opinion.
It's for fun.
Can't you just have fun for an hour and not try to diagnose your mystery boil?
We think you've earned it.
Just sit back, relax, and enjoy a moment of distraction from that weird growth.
You're worth it.
All right,
Tom is about to books.
one, two, one, two, three, four.
We came across a pharmacy with its windows blasted out.
Pushed on through the broken glass and had ourselves a luck around the medicines, the medicines, the escalate macabre
Hello, everybody, and welcome to Sawbones, a marital tour of misguided medicine.
I'm your co-host, Justin McElroy.
And I'm Sidney McElroy.
There's a lot going on, Justin.
There's a lot going on.
It's a very busy, very busy time in the world.
It is.
It's making lots of choices.
Yeah, a lot of choices.
A lot of big choices.
A lot of big feelings.
A lot of big feelings.
A lot of big choices.
Yeah.
And
I think sometimes we forget that things that happen maybe like on a national level, how they affect us as individuals in the government.
But then now I feel like we're all very aware of that.
Yeah.
It's really made it real.
Yes.
For better or for worse.
We are all very aware.
So there's a lot happening.
And
it is hard for me personally to do one thing at a time.
It's nigh on impossible, I would say, for this industry to drill down to just one thing.
Yes.
And I think right now there's a lot of noise out there, and that echoes what it's like inside my head.
And so this episode is reflective of that.
There's a lot of different things happening in my brain and in the world.
And so I wanted to share a few of those in one sort of collective episode.
Okay.
Not just current event topics, that's in there, but also just some pop med.
popular med
stuff that yeah that i thought would be fun some uh myth myth busting if you will yeah classic sharing about some some madeline one of our listeners brought to my attention thank you madeline some uh a new i don't want to say snake oil just yet but questionably
spoilers evidence-based product uh that's on the market and um i thought we would do that in sort of what we call in educational circles the sandwich model now speak on that so when i'm giving feedback to students or residents and this isn't unique to medicine, a lot of educators use this model.
We use the sandwich design, meaning I'm going to give you two pieces of positive feedback.
That's the bread of the sandwich.
And in between them,
I'm going to give you a piece of negative feedback or maybe something that's not so positive.
And that would be your meat, your turkey, or your peanut butter or your Vegemite, I guess, depending on where you are.
The filling, right?
So that way I start with something good.
I give you something maybe to work on, and then I end with something positive.
It's interesting, the metaphor, because I feel like the stuff in the middle of the sandwich is usually the star of the show.
You know what I mean?
It's the attraction.
Well, I have heard it.
It's funny because I always was just taught the sandwich model and I heard someone in a different field, an educator in a different field, refer to it as the, I can't say the word poop sandwich model, but you know what I mean.
Yeah.
Actually more gross to say poop sandwich, but I understand.
Yes.
Justin, would you like to demonstrate by giving me some feedback?
Yeah.
Sid, you are a fantastic mother to our children.
Oh, thanks.
And
I would say that you make every day a joy, and I love spending time with you.
And we have a lot of laughs together, and you're my best friend.
Well, thank you.
That was very sweet of you, and it means a lot.
You didn't.
You didn't actually give me any negative feedback.
I don't have any.
Oh, well, okay.
Sorry, but somewhere in the middle there would be
if you had any negative traits, I would be happy to put them out.
You get the idea.
I'm going to tell you something interesting and kind of fun, and then I'm going to tell you something about current events that maybe isn't as fun.
And then we'll end on a positive note with something silly.
How about that?
The chocolate coating makes it go down easier.
That's a sneak peek.
We will be talking about chocolate.
Oh, I didn't even do that intentionally.
Yeah, there is.
Chocolate will feature at the end of this episode.
So first of all,
Justin and I were watching a video where someone was making fried rice.
Yes.
And MSG came up, the topic of MSG.
Yes.
And specifically, what was referenced were the dangers of MSG and how certain...
groups of people, certain demographics should avoid consuming MSG.
This is, I'm so glad you're talking about this.
Yes.
The MSG controversy, I don't know that we've ever really, I think we have referenced it before on the show, but like dug into what does the science say?
Yes.
It's exciting.
We love.
Can I say, just, I feel like I should get this out there.
Yeah.
Next to our stove where we cook, we have a little rack with oils and spices and stuff.
Little rack's an interesting way of describing some beautiful
cash shelves that I handcrafted.
Big, beautiful shelves.
Big, beautiful shelves.
We have a lot of, they're not condiments, seasonings.
We have a lot of things that we have.
We do have a lot of condiments in your sauce drawer, but a different
normal way of dealing with
ingredients.
We like flavor in this house.
We add a lot of things.
Anyway, so among them,
and I would say to the front of the shelf, meaning we use it frequently enough.
The king of flavor.
Is the king of flavor
MSG, mono sodium glutamate, in a giant, like a comically large
buy bulk shape
in bulk we buy in bulk okay the kids the kids when when they get their soup if it didn't have some extra msg in there i don't know what they do they they love the king of flavor everybody in this house does you're trying on popcorn forget about it and can i say if you're a fan of roasted vegetables which we are
and we were always just doing some olive oil salt pepper throw it in the oven right like easy throw some msg on there too
quarter teaspoon of msg just a sprinkle of and just a little probably health health benefits, but I want to let Sidney talk about it.
No, I'm not saying they're health benefits.
What we're talking about
is this popular idea that MSG is somehow inherently bad for you, or that it makes, I think this is the myth, it makes Chinese food specifically bad for you.
And when I say Chinese food, I am talking about the Americanized
Chinese food that we go to like a, maybe like a Chinese buffet to eat, right?
So, first of all, MSG was first identified by a japanese chemist dr akita and this was all the way back in 1907 and the reason is that he was eating dinner with his family and he wandered he was eating a dashi broth and he noticed that it tasted better than normal
it was more delicious than it usually was
and he kind of investigated what is in here that's making this a tastier dashi than it usually is.
And he found kombu, which are little bits of algae, a little kind of algae.
And there were also some flakes of a fish.
And
he wondered, what is it in this,
he studied the kombu first.
What is it in this kombu that is this flavor?
This, this, what is this?
And you know where I'm going with this, but we didn't have the word yet.
We didn't have it.
Yeah.
So he didn't have, we didn't have umami yet, but he was, he was tasting it and he knew there was something there.
And at this point, right, we had salty and we had sweet and we had sour and we had bitter.
We didn't have umami.
This is just invented recently.
Well, he found it.
Well, yeah, I guess not invent, but like discovered.
Anyway, he was able to isolate glutamate.
And glutamate, and specifically monosodium glutamate, is a form that is the basis for a lot of what we sense in food as umami.
He called it a jinamoto, which means the essence of flavor.
So there you go.
We call it here MSG.
He could probably also call it MSG, either way.
And
he developed a process for how can we extract it from wheat and soybean, and then he patented it and then sold
MSG.
and also gave us the idea that there is a flavor that is called umami.
And I will say, like for our concerns about MSG specifically in Chinese food, because that's where it gets tied to, right?
A lot of people assume like that's where it is.
MSG worldwide is like, it's up there with salt and pepper.
So as an American on your table, you probably have a salt and pepper shaker.
Worldwide, MSG is...
almost as popular.
Probably salt and pepper gets the edge worldwide, but MSG is right up there.
So it is extremely popular and used in lots of different types of cuisine, lots of different food preparations, obviously not just Chinese restaurants.
However, back in the 60s, probably around the time that like people were popularizing eating out at a Chinese restaurant in America, there developed this concept of something called Chinese restaurant syndrome.
Do you know what that means?
If somebody, have you heard that term before?
I know.
It used to be in Webster's, so it was popular enough that it was in the dictionary.
It's kind of fallen out of favor because, as you may guess, it has some fairly racist undertones
since MSG is indeed used in many different types of cuisine all over the world.
But there was a collection of negative physical symptoms that people began to claim they would get if they ate out at a Chinese restaurant.
And it was tied to MSG is in Chinese food.
MSG makes people sick.
And Chinese restaurant syndrome specifically, it was usually something like a headache, dizziness, flushing,
even like neurological symptoms like my hands and feet feel numb.
You may have some nausea, those kinds of, like just this sort of vague collection.
It's very nonspecific.
Yes, it is very nonspecific.
And so people began to say that MSG caused this.
There was also the myth that MSG makes it impossible for you to be sated.
Have you heard this before?
That old sort of cliche about how if you eat at a Chinese restaurant, then you're hungry an hour later.
Yes.
And that's why you just keep going back to the buffet.
You can't stop yourself is because the MSG makes it so you just can't feel full.
So
anyway,
MSG from a food regulatory standpoint is considered safe.
Like a lot of...
additives in food, there are recommended values.
There are levels at which they recommend you don't exceed.
That's true for a lot of different things that we consider safe in food, by the way, not just MSG.
But why specifically did we ever think MSG was dangerous?
How did it begin to develop this?
Well, it may have some scientific basis in that glutamate itself does a lot of stuff in our body.
We already have glutamate.
We create glutamate through endogenous pathways, meaning things that are already happening inside your body chemically outside of what you're consuming, are making glutamate.
And it does a lot of stuff neurologically.
It has a lot of effects in your central nervous system, in your brain already.
So we know know that glutamate as a molecule does a lot of stuff in your body.
So then the idea would, it would be natural to question, well, if I am putting extra glutamate in my body, is that going to cause a problem?
And is there a level at which I would consume glutamate that would do the things?
that glutamate does right
so because we know that if you have problems inside your body already with how much glutamate you produce and how much you get rid of and all that it can lead to things like um neurodegenerative diseases like Huntington's disease and stuff.
Has nothing to do with eating glutamate, but does have something to do with the molecule glutamate.
Does that make sense?
Yeah.
Okay.
But if you look at all of the studies that then took that science fact, glutamate does a bunch of stuff in your body already and said, if I eat MSG,
will it hurt me?
We really don't have a lot of evidence to say yes.
First of all, most of the studies that have been done on MSG, and there's a huge
analysis that was done
in 2019, and that's where I'm drawing a lot of this data.
It was a really thorough look at all of the different preclinical and clinical studies, so meaning things that were done in labs, in rats, and then in humans, that looked at all of the alleged health hazards of MSG.
And it was published in the Journal of Food Science to say, like, okay, is any of this true?
And what they found is that, first of all, in the pre-clinical studies,
we are using amounts of MSG, and this is true in so many things, like with food additives, that far exceed what anyone would be expected to eat on a daily basis.
Do you know what I'm saying?
Very similar to what we heard about, like, uh, pops up about like artificial sweeteners and exactly, exactly.
If you eat several pounds of it, it could have deleterious effects.
Yes.
Now, even with that, in a lot of the studies, they still did not find any association with anything.
So even giving massive doses of whether it was looking at effects on cells in a lab, looking at effects on rats, or actually giving them to humans, we still really didn't find strong associations for many of the things that MSG was cited as a culprit of.
It was not linked with obesity.
It was not linked with asthma.
It was not linked with headaches.
None of the symptoms of quote-unquote Chinese restaurant syndrome have ever been found like collectively to,
you know, coincide with MSG.
No nervous system dysfunction, no pituitary dysfunction.
None of this has ever really been connected.
The other thing is when they did the studies in rats, and I think this is one, it's worth pointing out that a lot of these studies were done in rats.
And that doesn't, that might lead you to more research, but it doesn't give you a definitive answer.
They also, not only did they feed the rats MSG, in a lot of the studies, they would either inject them with MSG or even IV like intravenous MSG.
I've tried that as a time-saving measure and it doesn't make the food more delicious.
You would think that a sustained dose of MSG straight to the bloodstream would
add every bite that extra kick, but no, it doesn't work like that.
It makes you really sleepy and then lay down for a while.
Well, no, that's not.
There's no effect.
I don't know.
No, it doesn't, I mean, just a joke.
No, and they found like ways to give,
for instance, there was one study that was criticized because this was actually done in humans and they were actually eating MSG.
So this was a relevant design in that sense.
None of these are powered to really give us an answer.
And what that means is in order to tell the difference,
am I seeing an effect because there's an effect or am I seeing an effect because of coincidence?
You have to have enough people participating, right?
That's the, you have to power the study to be relevant, to give us math that will give us an answer, or at least lead us closer to an answer.
Most of these studies were nowhere close to that.
But in one study in particular,
they gave them so much MSG in their food.
They were eating, I believe it was a kind of soup, and they put so much MSG in the, in the soup that the participants could taste it to an extent that, I mean, if you eat enough MSG, I guess it can get this almost like bitter, overwhelming,
I don't know.
I mean, it's it's umami as the flavor, but it gets to be.
I've never, I've never taken a teaspoon of MSG and stuck it in my mouth.
It gets real funky is the best word that I can think of to describe.
It's like, whoa,
like funky.
It's too funky.
So, and they noted that, like, that was one of the studies where they said the participants did feel like they had like a headache or something afterwards, but they also ate so much MSG that they knew they were eating MSG.
Like, it was, there was no way applying the study because you put so much of it in there, you tasted it.
So, I mean, it was almost like you're trying to find,
you're trying to find a reason to blame MSG.
So the point is, from this big meta-analysis and from so far, from the studies we've looked at, when it comes to
the
kind of racist Chinese restaurant syndrome, which we probably just shouldn't say anymore, right?
We should probably just eliminate that phrase.
You're still saying it, Sydney.
That's what's so hurtful.
Well, no, I'm trying to address it.
It's not a thing, and so we shouldn't reference it anymore.
The more severe things like neurodevelopmental effects and inflammatory effects and all those things, there's really no evidence for any of that.
Could someone just be intolerant to MSG?
Yeah, that's true for anything, right?
Like it took me a while to figure out that diet shasta gives me a headache.
But diet shasta gives me a headache.
I know that.
That doesn't mean that diet shasta should be cocaine aminos, diet shasta.
Right.
Some of us can't tolerate different things.
So certainly there may be somebody out there who gets a headache when they eat MSG.
I'm not saying that doesn't exist.
What I'm saying is that the standard belief that MSG is a dangerous food and that specifically Chinese food at an Americanized Chinese restaurant and your standard sort of like stereotypical Chinese buffet kind of food.
is dangerous or bad for you inherently,
that has some questionable stereotypical origins and no scientific evidence to back up those claims.
Before we move on, my argument for
a health benefit of MSG is that
a lot of times, if you use MSG in cooking, it allows you to reduce the amount of salt that you're using because you're able to heighten the flavor without adding additional sodium.
So, if you're somebody who's trying to monitor your sodium or reduce the amount of sodium in your diet, then
introducing more MSG into your cooking can help you to reduce some of the salt that you're using.
A lot of salt substitutes are using MSG as an ingredient to try to offset the amount of sodium.
Which I will say, sodium is not bad, again, across the board.
Salt is not, quote unquote, a bad thing.
I added the important corollary that if you're trying to watch your sodium.
Right, if you are someone who needs to limit your sodium.
Absolutely.
Absolutely.
One last thing I should note about MSG that kind of undermines all this.
There is a lot of the studies have shown that the amount you're eating of, first of all, you're eating glutamate in lots of things, not just an MSG.
And secondly, you metabolize a lot of that.
The amount that actually gets into your brain and nervous system after you ingest it is so minimal.
Like
we've broken it down that it would almost be impossible for a lot of these things to ever be true.
So I feel like that's worth mentioning too.
So there you go.
There you go.
Put it on your roasted vegetables.
Delicious.
Do you want to move on to the middle of the sandwich or do you want to take a break first?
No, I want us to go to the billing department first.
Let's go.
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You know, we've been doing my brother, my brother me for 15 years, and
maybe you stopped listening for a while, maybe you never listened, and you're probably assuming three white guys talking for 15 years.
I know where this has ended up, but no, no, you would be wrong.
We're as shocked as you are that we have not fallen into some sort of horrific scandal or just turned into a big crypto thing.
Yeah, you don't even really know how crypto works.
The only NFTs I'm into are naughty, funny things, which is what we talk about on my brother, my brother, and me.
We serve it up every Monday for you if you're listening.
And if not, we just leave it out back and goes rotten.
So check it out on Maximum Fun or wherever you get your podcasts.
All right, we're over 70 episodes into our show.
Let's learn everything.
So let's do a quick progress check.
Have we learned about quantum physics?
Yes, episode 59.
We haven't learned about the history of gossip yet, have we?
Yes, we have.
Same episode, actually.
Have we talked to Tom Scott about his love of roller coasters?
Episode 64.
So how close are we to learning everything?
Bad news, we still haven't learned everything yet.
Oh, we're ruined!
No, no, no, it's good news as well.
There is still a lot to learn.
Woo!
I'm Dr.
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I'm Caroline Roper.
And on Let's Learn Everything, we learn about science and a bit of everything else too.
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Join us every other Thursday on Maximum Fun.
All right, now, Sydney, this is the part that we did need to touch on and we want to talk about.
So I feel like we should, as I said, I think...
The midpoint of the sandwich.
Yeah, the midpoint of the sandwich.
I feel like I should continue to update us on things that are happening in health news in the world and then more specifically in the US, because a lot of things are changing with federal sort of health and science policy.
One thing that just recently an article came out about is that the CDC is going to change its recommendations for COVID vaccines.
Now,
the efforts of the federal government now to
undermine public faith in vaccination, I think were expected.
We knew this was coming, right?
We know RFK Jr.
has long been an anti-vaxxer, has long caused a lot of people who wouldn't otherwise question the safety of vaccines to do so and maybe choose not to vaccinate their children as a result.
We know that.
That effort has been underway for a long time.
So it is not shocking that they are now changing their recommendations on COVID vaccines to undermine the importance of getting vaccinated.
The move is going to
state that only high-risk individuals should receive COVID vaccines moving forward, specifically people over 65, people 65 and older, and
people with certain high-risk underlying health conditions.
What this will mean is that
more than likely insurance will not cover it.
for anybody who doesn't fit into those groups.
And also, if it hasn't been necessarily tested in a certain age group, it's not even about whether or not you can pay for it.
You can't get it.
Right.
Does that make sense?
There's kind of two levels here.
There are meds that, yes, they are safe in your body, but your insurance isn't going to pay for it.
And then there are meds that we didn't even do the test to find out if they're safe for you.
So we're not going to prescribe them to you.
And also, your insurance wouldn't cover them.
Right.
Okay.
So two levels there.
Obviously, this is concerning.
It's concerning to me on multiple levels.
One, it makes people people think that COVID is less of a big deal and that it is only a threat to those age groups and to those to those demographics, which we know is not true.
That is not evidence-based.
That's not science-based.
Two,
for someone like myself, I will say I work in healthcare.
I like to get every vaccine I possibly can so that I am not a risk to my patients who may fit into these groups.
As of yet, there is no caveat for people who work in those professions where they may expose people routinely, you know, who are in high-risk groups.
Also, there are a lot of people at risk for COVID who don't fit in necessarily to this criteria.
For instance,
up to last August, the year that ended in last August, there were 150 pediatric deaths from COVID.
That's about what you see in an average flu season.
And we recommend flu vaccines for children.
So I guess my question would be,
why are we comfortable with with sacrificing 150 children a year to COVID unnecessarily?
Would be, I think, a question that would be interesting for RFK Jr.
to have to answer.
Or the two doctors at the CDC who are noted vaccine,
I don't want to say deniers, but skeptics who are making this new CDC health policy.
Now, what I would encourage you to do, because we can't, we're not going to be able to change this policy, right?
And what it will do to vaccine manufacturers in terms of how much of the vaccine is available and how much effort is made to get it out to people and how much insurance covers it.
We're not going to have a lot of impact on.
But what you could do is go to cdc.gov and look up the list of underlying conditions that make you at higher risk for severe COVID because
as it sounds like it will be the policy will be stated, people with these underlying conditions will still be eligible for a COVID vaccine.
And there's a lot of them.
So a lot lot of people, maybe up to a third of Americans, may still be eligible to receive a covered COVID vaccine.
And so I would really highly recommend there's stuff that you might expect, like lung diseases, you know, that makes sense for something that can have respiratory effects.
But there's also obviously more serious illnesses like cancer.
But things like chronic kidney disease or chronic liver disease, diabetes.
There are heart conditions.
There's some mental health conditions that are listed specifically.
So mood disorders, including depression.
So there are a lot of maybe unexpected underlying conditions.
Wait a minute.
Hold on.
If I find it depressing that I can't get that COVID vaccine, oops, somebody just found a loophole.
You know?
Well,
it's interesting because as I was looking through this list of,
I mean, I'm worried about everyone.
I'm worried about people I know personally, my family and friends.
I'm worried about my patients, my community, but I'm worried about you listeners as well.
So I, I, but I don't know all of your health conditions, so I can't go through each of you.
I was going through mentally everybody I know personally and their health conditions and how many people I could get a vaccine for based on this list.
And I was surprised how many people I could continue to advocate like, you, hey, you qualify, you qualify.
So I would encourage you to go look at that list because you may be eligible for one and you didn't know that you were.
Obviously, everybody 65 and older should get it.
And as many of us who qualify should, because again,
everyone who gets vaccinated is protecting people around them.
And so the more of us who are able to do that, I don't understand why these doctors at the CDC now don't get it.
I don't understand why RFK Jr., well, I get why he doesn't get it.
He doesn't seem to get much science.
But check that list out.
That is an action you can take.
You can advocate for people who can get the COVID vaccine to get the COVID vaccine.
And you can still use other mitigation methods.
You can still stay home when you're sick.
Encourage others to do that.
Make policies that make it easy for people to stay home from school or work or whatever when they're sick to work remotely.
You can wear a mask when you're in public in large groups.
You can do things to mitigate the spread of COVID outside of vaccination if you are not eligible to get a vaccine.
And also, just a reminder that these corporations could cover whatever they wanted.
It's a good point.
I mean, I obviously the blame should be squarely pointed at the government, but if these companies believe that it is of a health benefit that you are vaccinated from COVID, and I mean, they could cover whatever they wanted.
I mean,
period.
Yeah, they could do the trials in all ages and continue.
Well, they could continue to produce vaccines, and then you need to lobby the insurance companies to cover them.
But again, we have two big players in the world.
Right, but
that's what I'm talking about.
The insurance companies could cover them.
Yes.
I mean, the pharmaceutical makers could make the, I mean, like, it is, it is,
there are, if we are going to cede all of our, our, like,
um,
health decisions over to corporations, then they're going to have to
be, you know, then we have to hold them accountable as well.
Or, like, who, who else can we hold accountable?
Well, I mean, I think that's you're what you're hitting on is the problem.
The these government regulatory agencies are supposed to, right?
Right.
But now that the government and big business are fusing into a single sort of force in this country, it will be harder and harder to make that happen.
Yep.
But you can advocate, I mean, and continue to do all the things you do with advocacy.
And you can, this is an easy thing.
Go to the CDC website, check out all of the conditions.
I can't guarantee that once, I mean, and I will say, even, even in the articles where the where the CDC doctors are talking about how so many Americans will still be eligible for vaccines.
And these are,
again, Dr.
Prasad and Dr.
McCary, who are skeptical about COVID and COVID vaccines and always have been, are still saying that
about a third of Americans will still be eligible.
So hold them to that.
Justin,
the other news thing, I'm not going to talk much about.
Casey Means was picked.
as the new possible surgeon general.
She still has to have an approval by the Senate.
So
that hasn't happened yet.
But I did want to note, so Casey Means finished medical school training at Stanford.
And then at some point during her residency and I believe surgery
left
for whatever reason, she says because she realized how broken the healthcare system was and wanted to do things on her own.
So she wrote a book called Good Energy about metabolism and limitless health.
And I mean, she's, she's a lot, she, she touts a lot of the things that RFK Jr.
talks about in terms of how we could prevent all disease with just like good diet and exercise and less medicine or whatever.
Anyway,
obviously that's concerning.
It's questionable.
I think a lot of people are upset because she's not a licensed physician.
She did finish medical school, so the MD is legit, but she did not.
She's not a licensed practicing physician, and as far as I can tell, never was.
I am going to find a way to obtain her book,
Good Energy, without
giving her money.
I need to go to the library
because I really don't want to give this woman any money.
And then I can give you more of a breakdown on her in the future.
Looking forward to that breakdown, Sidney.
The last thing I want to tell you about Justin is sex chocolate.
I smell sex and candy.
So
this is not news.
per se.
Madeline, thank you for bringing this to my attention.
And this is, this is, this can be lighthearted.
There is a sex chocolate called tabs that is available for you to purchase.
It's almost, they look like they're like little things that like melt on your tongue, chocolatey
things.
Place a tab on your tongue, let it dissolve, and feel the effects in five to ten minutes, is what they say.
They have
three different kinds of tabs.
Okay,
there's uh
chill,
play,
and groove.
Oh.
So it depends on, I guess, what you're in the mood for.
So
what's happening in them?
So play, which is the sex chocolate, they call it sex chocolate.
So sex chocolate has, obviously, it's got cocoa in it, it's chocolate.
It's got something called epimedium.
And this is all on their website.
You can look at all their ingredients.
And they tell you that it boosts libido and initiates arousal.
Now, let me tell you what that is.
That's horny goat weed.
So you may have heard of that before.
It has been used in traditional Chinese medicine for centuries as an aphrodisiac and as a performance enhancer.
And I will say, I read into the physiologic activity.
What does this thing do in the human body?
It inhibits something called phosphodiester diesterase type 5
in vitro.
This has not been shown in the human body.
In vitro means in a lab.
However,
PDE5 inhibitors.
In short, that's what Viagra is.
So it does have some effect, at least in a lab that viagra has so there would be now granted that doesn't necessarily mean that when you put the amount that's in tabs chocolate in a human body you're going to have a viagra like effect
no um there was a rat study which i was reading this study justin and i thought this feels like a nightmare study for you where they gave
They gave horny goatweed to rats and then measured their erections.
Super horny rats.
Yeah.
I just, I felt like the idea of, of,
you never think that a life in science, a life dedicated to science, is going to involve measuring rat dongs, but I guess it does, huh?
It did.
And they showed a difference in rat dongs after exposure to horny goatweed.
I think what the study I want is effects on the psychology of rats after having their dongs measured, because I bet it wouldn't even...
I bet it wouldn't even occur to them to even think about it before.
But then maybe after the science guides measure, then the rats are in their heads about it.
You know what I mean?
Like, well, I don't know.
I've never thought about it.
Huh?
I don't know.
Is it?
I don't know, Doc.
You tell me, man.
Is it typical?
I don't know.
Thanks for the chocolate, by the way.
That was, that was actually awesome.
Thank you so much.
That's like the, I gotta say, doctor, this is absolutely the best day I've had as a lab rat.
Guaranteed.
Like, this is like primo.
Let me just say, I have no evidence that the makers of Tab Sex Chocolate gave the chocolate to rats.
I'm saying that the component, the component horny goat weed has been studied a lot.
Like a lot of supplements, I don't have a big clinical trial to tell you that it, and certainly that it would work better than Viagra.
I wouldn't think that because
we use Viagra.
But anyway, there may be some basis for that.
The maca root is the other thing that's in there.
It stimulates blood flow.
It has, again, been used for libido and mood and erectile dysfunction, but it's not conclusive.
And the one thing I will say is this one may or may not interact with estrogen and testosterone receptors.
It says both.
Studies have indicated both or haven't.
So it is unclear at this time if it does interact with hormone receptors, but it might.
And so that did make me a little nervous because there are certain like cancers and things that are hormone sensitive.
And I don't know.
I would, I just, anything like that that we're like, I don't know, it might have some huge effect in the human body.
We're not really clear yet.
It makes me nervous to just be like, so eat it.
But again,
it's probably such small amounts that it's not doing anything.
But I don't know.
So that and maca root has been using lots of different different supplements and things like this for this.
And then there's kana is the third ingredient, um, which is supposed to create relaxation and warmth.
This is another that has been used for centuries, um, in sort of like folk medicine by different populations of people around the world, and it was kind of a cure-all in some areas, like narcotics, sedative, analgesic, toothache, constipation,
uterine contractions, um, all kinds of stuff.
It's been used for euphoric effects effects at times because it can have a little bit of an ecstasy thing.
It does work on the brain, on some mood things, like it has
serotonin
reuptake blocking.
So similar to like a selective serotonin reuptake inhibitor, SSRI.
Well, it just makes you happy.
That's nothing.
Well,
this specifically has been put in the chocolate.
This isn't chocolate.
This has been put in the chocolate.
It already makes you happy.
It may have some effect on
extra SSRI if if i'm already eating chocolate there's no conclusive evidence for any of this by the way all of this is like maybe maybe eh i don't know is it enough is it really how much would you have to eat i don't know but those are the ingredients that's why they make the claims they make the chill and groove types have the kana and then like theobromine which is just a chocolate thing that's already in chocolate that's not special that's just chocolate and then l-theanine which we've talked about before on the show i think in your like brain enhancer remember we talked about like brain enhancer supplements.
That's what's in them.
But
the TABS website says these statements have not been evaluated by the Food and Drug Administration.
Also, Food and Drug Administration isn't capitalized.
So it's like just any Food and Drug Administration has not approved of this.
No.
So, I mean, I don't know.
They're chocolates with extra stuff in them that
probably won't do much of anything.
They have a lot of discount packs.
Okay, we don't need to do a sales anymore.
That's what Tab Sex Chocolate is all about.
Justin, I would tend to agree with you that chocolate makes you happy.
Yeah, so it's probably not going to be, I don't know if it makes your ding-dong do stuff, but who knows?
Neither does tabs.
And there's probably, I would say, I don't know the quality of their chocolate.
I have no comment on that.
I've never tried it and they don't tell me.
But I would bet that there's better quality chocolate for less price that you can access
locally.
Yeah.
Thank you so much for listening to our podcast, Sawbones.
We want to say a big thank you to the taxpayers for the use of their song, Medicines, as the intro and outro of our program.
We've got some Sawbones merchandise over at macromerch.com.
If you've never read the Sawbones book with illustrations by Sidney's brother Taylor, you should absolutely do that.
The paperback has new content that was not in the original hardback edition.
You can get that anywhere.
Fine books are sold.
We actually found the there was a version adapted into
Chinese or adapted into.
I know I bought it from Taiwan, but I'm not sure in what I'll do.
It was, yeah,
it
was really cool.
Yeah, very cool.
That's going to do it for us this week.
Until next time, my name is Justin McElroy.
I'm Sidney McElroy.
And as always, don't drill a hole in your head.
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