123. Dr. Peter Diamandis: The Future of Health with Stem Cells, Blood Filtration, & AI

Our bodies were never designed to live past age 30.

Our muscle mass starts decreasing after the age of 30. Our hormone levels, our muscles begin to atrophy.
I don't think that the majority of Americans even think of muscle as an organ. They don't think of it about being our metabolic currency.
There's a direct correlation between the amount of skeletal muscle you have and your longevity. Fundamentally, it comes back down to diet, sleep, exercise, and mindset.
And the way that you do those things is to wrap routine around them. Sort of the discipline over motivation.
We've actually gotten away from the basics, the basics that you just talked about. Most people are healthy till 63.
And our goal here is, can we at least move your health span up to that 80 year mark? this is the decade of a health span revolution and the biggest impact is going to be coming from ai when you have artificial intelligence that can take 700 trillion independent variables and create an actionable result and no human can understand all that but ai can take it all in process it and help you and ultimately it's about being in the best health i can in order to intercept these breakthroughs. We're both on the same journey, you know, this childlike

fascination with longevity. What are just the basic building blocks of somebody who wants to

live a long, healthy life? Yeah, one of the best anti-aging, biohacking, longevity, and everything in between. And as you just heard, today's guest is probably one of the most iconic guests that we've had on the podcast in a long time if not the most iconic guest i'm an enormous fan of his we were actually just fanboying over each other and he's like i'm a fan of yours i'm like well i'm actually a fan of yours i'm i've been following you for longer but uh welcome to the podcast, Dr.
Peter Diamantis.

My pleasure, Guy.

It's amazing to be here with you in beautiful Miami and in your incredible environment here. You walk the talk, you live it, and so proud of what you've built.
Thank you so much. I mean, that is a very high compliment coming from someone like yourself.
You know, I've actually been following your trajectory from, you know, from afar for several years now. I kind of find it fascinating how I think you're one of those rare kind of left brain, right brain kind of entrepreneurs that's able to get deeply embedded in the science, but also see how it can have a practical application to humanity.
And we're both on the same journey, you know, this, this, this fascination, this childlike fascination with longevity and, and the extension of life. And, you know, I want to go down that road with you a little bit because, you know, as I've traveled around the world and met with some of the brightest minds and seen all the biohacking equipment in the world, and we're going to talk about some of the things that I think are fascinating, both of us in the space of longevity.
The one thing that seems to stick with me is that we need to get back to the basics and then advance to the fancy stuff. And what is your feeling on that? I mean, what are just the basic building blocks of somebody who wants to live a long, healthy life? I think about that a lot.
And I'm clear that fundamentally, there are a whole slew of things that cost you nothing that have a huge impact right now.

A lot of people know me as a technologist or investor in biotech or AI and building companies in that field. But what I really want to gift in this conversation with you is like what you can do right now that moves the needle for you.
And it's not spending hundreds of thousands or millions of dollars. You can do that as well, but fundamentally it comes back down to diet, sleep, exercise, and mindset.
Those are the elements that if you don't have those dialed in, you know, forget about the other stuff. Let's dial those in.
And, you know, we're here discussing my latest book, longevity guidebook, how to go, you know, how to slow, stop, reverse aging and not die from something stupid. I love that.
Not die from something stupid. It's important because I think that should have been the title of the book is such a great tagline.
It really is. Thank you.
But you know, it's there. So there's there's a chapter on diet, a chapter on sleep, a chapter on exercise, a chapter on mindset.
And importantly, this time, a chapter on routines. Because I think the single greatest innovation, I'm 63 right now.
I feel like I'm in the best health I've ever been in my life. You look amazing, by the way.
You're a lot more jacked than you look on camera. I added 10 pounds of muscle last year.
Really? I went down, you know, muscle is your longevity organ, and I went full on. Did you do full statin gene therapy? No, no, no.
It was working out in the gym with weights every day, five days a week. It was creatin.
Creatin, it was 150 grams, because I weigh 150 pounds of protein every day. And it was doing the work.
It was doing the work. Now,

doesn't mean, and we can talk about this, some amazing biotechnology coming in the future that will make it a lot easier. My job now is to maintain that.
But lots of studies around the world show that there's a direct correlation between the amount of muscle mass, skeletal muscle you have and your longevity. So again, the chapter on diet, a chapter on sleep, a chapter on muscle, a chapter on mindset, those are things that we should be doing now.
And the way that you do those things is to wrap routine around them. Yes.
You know, what is routine? It's not negotiating with yourself over and over again. Right.
Right. It's like waking up in the morning and like, this is who I am.
Sort of the discipline over motivation. It is discipline or that's a good point, a good way to put it.
Um, and it's like, it's, it's creating that person who you want to be in who you are. So it's like, I am the person who gets up at this time and does these things.
And when you identify with that, it helps you not negotiate and say, well, you know, I want to stay in the cuddly bed a little bit longer or that dessert. I can rationalize eating that dessert right now.
Yeah. You know, it talk about this a lot too.
You know, in some of my workshops, I talk to a lot of folks and it's interesting how people think that self-care is very selfish, right? So, you know, I've developed this philosophy that, and I apply it every day, that the first 90 minutes of every day belongs to me. Yes, your golden hour.
Yeah, it's just my, it's my golden hour. And it doesn't belong to my spouse or my employees or my clients or my partners or even to, you know, my podcast.
It belongs only to me. And it sounds very selfish, but then I just give the rest of my day away, right? I'm very intentional with my children, my spouse, with my team, you know, with the clients.
I'm able to be very present with them. And for me, it's been an absolute game changer.
And then I put some non-negotiables, simple non-negotiables into my schedule, you know, where I schedule all of my meetings and travel around sleep and exercise. Yes.
And I'm not the fittest person in the world.

And I get some nights where I don't get good sleep. But by and large, you know, my sleep scores are 96% plus.

And I don't go a day without doing some kind of physical exercise.

It has had the most dramatic change on the amount of enjoyment that I get out of doing what I do.

Yeah. I agree with you 100%.
So I have the same philosophy. I'm up typically at 530 in the morning.
And that starts by being in bed by 930 the night before. Right.
So I'm at my Abundance Summit. I've got 600 CEOs, people from around the world.
They're partying hardy. And they watch me.
They say, Peter, come on. Sorry, it's bedtime.
Yeah. So I'm out of my own events at 930, you know, at nine to be in bed by 930.
And then when I get up at 530, that first, really it's the first 90 minutes. It is my golden time.
And it is, I love writing during that time. So I'm writing every day.
I've got three books in production.

This is the first of the three. I'm very excited about this.
Thank you. And, um, and, uh, you know, I put out two blogs a week, but I'm in the gym, uh, doing red light therapy, meditating.
And it's, it's that period of time that, like you said, it's selfish. It's mine.
And it allows me to perform at a much higher level. Now, to be clear, I wasn't always that way.
Right. And it doesn't mean you go from zero to infinity.
I got there over time. I wasn't that way a decade ago.
I got into longevity. I'd started human longevity with Craig Venter of Bob Hury back in 2000, uh, 2000 uh 2012 that is that makes you a great grandfather yeah i got i got just the father of longevity i got brian johnson into longevity it's very funny you know it's awesome yeah well he definitely caught the bug he did yeah we were talking about this before i think he's showing us what's possible, maybe not what's practical.
And I say somewhere between the intersection of a Brian Johnson and, you know, and what we're talking about here. I think that's really important because there are very practical things.
It really is an 80-20 rule. You know, if you feel like you have to do it all to get that additional health span, right? And let's upfront say, it's not really lifespan we're talking about.
It really is health span. You know, today, the average lifespan in the United States is call it 79, but the average health span is 63, meaning you're living till 79.
Hopefully everybody here is going to have a vision of living well. My my listeners are going to live to 120.
Yeah. They're fantastic.
Greatly offended by what you just said. I'm sorry.
I'm just kidding. Apologies.
But the reality is that most people are healthy till 63, then there's a 16 year gap. Yes.
And our goal here is, can we at least move your health span up to that 80 year mark? And yeah, I believe that this is the decade of a health span revolution, of a lifespan revolution as well. And, you know, half my life is in the longevity world.
Half my life is in the AI world. And the biggest impact is going to be coming from AI.
I agree with you. Right.
We're a collection of 40 trillion cells. Every cell is running one to 2 billion chemical reactions per second.
And there's no way for any human to understand the vastness of that, but AI can. And we're going to be making discovery after discovery after discovery, but it all begins with sleep, diet, exercise, and mindset.
Dial those in first. Yes.
And then get ready for an extraordinary ride in the decade ahead. Yeah, I totally agree with you.
I think that about every half decade, we're going to see three centuries of medical advancement. And what I mean by that is when you have artificial intelligence that can take 700 trillion independent variables and create an actionable result, when you stop doing clinical trials where you study things in isolation, you know, you take a cell out of the body, you look how it behaves in a petri dish, and then you assume that when you put it back into its community, that it's going to behave the same way.
I think, you know, you're talking about leaps and bounds.

And, you know, I mean, I think the old arcane, in my opinion,

you know, randomized clinical trial, placebo-controlled trial

that takes, you know, eight or 10 years

and then comes out with a compound that, let's say, gets FDA approved

and then goes into the market for 10 years and gets data.

And by the way, it only works for 20% of the people who it's prescribed for.

Thank you. comes out with a compound that, let's say, gets FDA approved and then goes into the market for 10 years and gets data.
And by the way, it only works for 20% of the people who it's prescribed for. Right.
And you don't figure that out for 20 years, you know, until you get really large data and they go, well, we made a mistake and we either pay a fine or take something off the market or change it up. I mean, those cycles are so long.
And then I think we also have the inhibition, and I don't mean this in a negative way, but the, you know, the regulatory environment just doesn't have the capacity to keep up. I mean, the, with the pace of innovation.
So I think that stalwarts a lot of what people have available to them. So, you know, a lot of treatments that I believe can really can extend life or at least extend health span, stem cells exosomes uh natural killer cell treatments yes blood filtration and we can talk about all of those yeah and i i actually want to go down that road first of all i'm glad that we agree on the foundation because i think that the greatest shift in humanity like when you i i was a mortality expert for for many decades and the biggest shift that must have been a great line for opening up your dating conversations.
Don't, chicks love mortality experts. They love them.
I mean, you can predict death to the month, man. That's a great party trick.
Here, give me your wrist. Let me feel your pulse and I'll tell you.
But yeah, I think my wife would probably disagree with that. But, you know, what's really interesting is, you know, there's so many people that are fascinated by this life extension, you know, extending our lifespan.
And I believe that there's evidence-based modalities and things that we can do, but they're just not available in the United States. You're going to travel outside.
And hopefully that will change in the new administration, right? Under RFK. And there's so much, it's a disservice that some of my closest friends, some of our members at Fountain Life to get advanced therapeutics need to travel outside the U.S.
to, you know, to Costa Rica or Mexico or other places. And that is all going to change.
The data is going to materialize as well as regulatory reform to support that. You know, and so, you know, having been a mortality expert, we studied long,, and lifespan.
And the, the greatest advances in life expectancy weren't like major medical breakthroughs or, or specific tinctures. They were, uh, sewers, sanitation, sanitation, vaccines, pasteurization of milk.
Yeah. I mean, these were, there was a massive jumps in, in life expectancy.
And I think now what's happened because I think that aging is the aggressive pursuit of comfort and people don't want to challenge themselves anymore is we've actually gotten away from the basics, the basics that you just talked about. Um, and, um, I, I don't think that the majority of, of Americans even think of, of muscle as an organ, right? I mean, mean you know they don't think of it about it being our metabolic currency yes um and so i want to talk a little bit about that and then i want to get right into some of the things that are really exciting you like blood filtration stem cells exosomes some of these some of these amazing things coming i mean should we should we hit some of the the basics so that coming out of this podcast people have some actionable items right away? Yeah.
Yeah. And I mean, most people aren't going to go, hey, I'm going to Panama and getting a $25,000 stem cell IV.
But let's break them down. First on diet, it is, if you think about your body, your genetics, what powers you evolved 200,000 years ago on the savannas of Africa.
And our DNA has not changed very much in 200,000 years. And back then, two things were true.
Number one, there was no sugar in the environment. You had some small amount of natural fruits.
There was no refined sugar. And the second was there, you know, feeding was intermediate.
Um, there was no defined gluttony of food consistently. We didn't have whole foods or, or McDonald's.
And so, um, today what I tell people, if you want to go on the diet front, uh, what you can do for yourself, number one, it's cut out this poison called sugar. Sugar, refined sugar, is a neuroinflammatory,

a cardiac inflammatory. We just did a study at Fountain Life in which we looked at cardiac disease as a function of a bunch of things like LDL, HDL, triglycerides, LP little a, all these things you hear about.
And the number one correlate to heart disease was none of those things. It was your hemoglobin A1c.
It was, what was your average blood glucose levels over the last three months? And so sugar correlates with heart disease. It also correlates with obviously diabetes and correlates with neurodegenerative disease.
So you minimize that uh first and foremost and it takes a while sugar is addictive um but i've trained myself

to minimize that in my diet we actually ran a uh a no sugar challenge for 22 days that a friend of mine um guillermo never for my abundance community. And if you do it as a group, it's a lot easier to do.
Yeah. Whole plants, of course, everybody talks about whole plants.
It is true. I'm not going to go, you know, plant versus animal protein.
I mean, minimizing sugar, whole plants, even the order which you eat your food, right? So when you're sitting down at your plate at lunch or dinner, eat the vegetables first, which is the fiber going through your stomach and small intestines. It slows it down.
It allows you to absorb nutrients, eat your protein next, and then eat your carbs last if you have room. Just doing that will flatten your couldn't agree with it your your insulin curve and help you lose weight anyway i mean those are just some a few mobility i mean you know and i think when you look at blue zone dieting or blue zone diets there was no really specific continuity between diets other than that they were all whole foods i mean mean, Sardinia was very different from the Mediterranean,

very different from Singapore.

You'd have very high meat consumptions,

long life expectancies,

very high carbohydrate consumptions

with long life expectancies.

And then you had very high fat consumptions

with long life expectancies.

But they were all whole foods.

And none of those people were eating a processed diet.

You didn't find the herbicides, pesticides,

asexocides, glyphosates, the red, the red dye number 40s, you know, all the things that we invented in the agricultural world evolution. And we slowed it down a little bit, right? I mean, at the beginning of your meal, take a deep breath.
I love that. Put yourself in a parasympathetic mode.
Say gratitude. Chew the food 20 times.
You know, we talk about all these GLP-1 drugs. You can induce that same impact by just chewing your food and eating slowly.
Yeah. Yeah.
I mean, I don't think most people realize that the GLP-1s, the semaglutides and terseptides, these are just mimicking hormones that we produce in our gut and um and they respond to they create satiety based on nutrient density and um you know so so when you're eating highly processed foods they're not nutrient dense you're hungry more frequently um and you have tendency to overeat um it's crazy i've been saying you know our kids cereals should have black box warnings on them like a cigarette yeah yeah i agree with that i totally agree with that there's a big movement to get kellogg's to take you know the food dyes uh you know out of the out of the cereals i'm i'm like why don't we just get rid of the cereal i mean you know we you know taking the the food die from red dye number 40 to a beet juice

die is great i mean honestly we're marketing this to our kids yeah yeah it should be it should i i think this has i mean this is a whole different conversation but this has to go to with you know the corruption in our you know the our research institutions and the and the stranglehold that big food and pharma has on our public policy and that research needs to be independent i mean nih needs to be a my opinion it needs to be a publicly funded taxpayer funded independent well i hope under rfk that this will make some significant changes whatever your politics make america healthy again fundamental stuff yeah i mean it's hard to disagree with um you know this the statistics you know the highest rates of childhood cancer in recorded history. We just now, as of December 6th, I just saw this article in the Daily Mail.
As of December 6th, we're ranked 66th in the world in life expectancy. Four and a half trillion dollars a year we spend on healthcare.
And we're ranked, I mean, our ROI on healthcare is horrible. It's negative.
So in the category of diet, it's not that difficult, right?

It is drink enough water. I don't do sodas.
Um, caffeine, I'll, you know, it depends on what your genetics are. If you're a slower, fast metabolizer, I've minimized, um, alcohol, like to half a glass of wine socially a week, but you know, it's a good lubricant for social, but don't abuse it.

It is another form of sugar.

But minimizing sugar, eating whole plants,

if you do just those two things and slow it down when you're eating your food,

really hard.

And don't watch the Crisis News Network while you're eating your food.

Don't be in a sympathetic state while you're trying to eat your food. All right, let's get into the good stuff because I think we are- Can I hit one more thing, which is mindset? I think people don't recognize how powerful mindset is on your health.
And there's a study I just want to quote in here that I write about in the book. By the way, I'm going to put a link to the longevity guidebook in the show notes below.
I mean, this is available now, but before you sent me a pre-copy. Yes, it is available.
I am donating 100% of all profits to the XPRIZE Foundation. We've got a, uh, a large health span prize I'll, I'll mention.
Um, I also, uh, you can order on Amazon great 26, 27 bucks. Uh, I have it available.
If you go to longevity guidebook.com, it's like $12 cheaper. Uh, and it's basically, I do it at break even, uh, I want to get this out there for me making, you know, a few bucks on a book is not the goal.
It's how do I get this out there? People should be empowered. This is the most extraordinary time ever in human history.
I want to watch and see and participate in as much of it as possible. Me too.
And I want people to have that vitality, that love, that life, that health. All right.
So here's two, two data points here on mindset. Cause I think mindset is one of the most important things that people don't connect to your longevity.
So this is in a study of 69,744 women and 1,429 men. So it's a large powered study, many more women than men.
Published in the prestigious journal Proceedings of the National Academy of Sciences, you don't get higher level than that. It was found that optimistic people live as much as 15% longer than pessimists.
It's like a double dividend. Wow.
And if you're not optimistic, get around people who are optimistic. Yes.
Here's another fun, and this is the power of mind over death. So it's one of my favorite stories coming from the Annals of American History.
So as it turns out, in an extraordinary demonstration of the will to live, two of America's founding fathers, Thomas Jefferson and John Adams, both willed themselves to live long enough to see the 50th anniversary of the Declaration of Independence. Even though the average life expectancy was only 44 years old in the early 1800s, Jefferson, who was 83, and Adams, who was 90, made it to July 4th, 1826, both dying on that exact date, the 50th anniversary of the nation they had founded.
Wow. Isn't that powerful? Wow.
I mean, if you, another friend, you know, Dan Sullivan says, make sure that your future is bigger than your past. Yeah.
Having a purpose to live for. Yes.
Is so important. That actually came out in the Blue Zone research too.
Yeah. The sense of purpose, sense of community.
Yes. Mobility into later in life.
You know, we know from the mortality research that the group I did was a part of that sedentary lifestyle is now the leading cause of all cause mortality. Sitting is the new smoking.
Yeah, it really is. It's the new smoking.
Hey guys, I'm really excited to announce this. Perfect Aminos has gotten a serious upgrade.
They've added nucleotides, the building blocks of our nucleic acids, DNA and RNA. And this is important.
We know essential amino acids are the building blocks of protein and collagen. Having all the essential amino acids in the correct ratio is necessary for complete protein synthesis without the caloric impact.
But if we want perfect protein synthesis, we need to look at the process of protein synthesis itself. Because if the process is faulty, we won't get the correctly made protein, collagen, fibrin, or the red blood cells in our bloodstream or our muscles.
We can even stop creation of specific proteins, which can affect us in so many different ways. Our DNA and our RNA are what direct protein synthesis, building new proteins.
If our DNA or RNA get damaged from toxins, harmful bacteria, or just plain aging, we get faulty protein synthesis. So cells, enzymes, and hormones are less functional and we get premature aging.
By adding nucleosides and nucleotides, the building blocks of the nucleic acids DNA and RNA, our cells get exactly what they need to help repair faulty DNA and RNA and improve the process of protein synthesis itself. This is next level science, and you need to try these.
Now let's get back to the Ultimate Human podcast. We both have that childlike curiosity and fascination with the extension of life.
And I think the majority of the really promising research has gone into the serum of the blood, through the wall of the cell, through the cytoplasm, and into the mitochondria. And I think we know mitochondria are not just the powerhouse of the cell, but they are the key, in my opinion, the opinion of many to longevity.
So what are some of the things that are really exciting you? I asked you this question the other day when we were on a Zoom call and I really enjoyed your answer, but what's some of the things that are really waking you up in the morning and exciting you about the field of longevity? Yeah. So, uh, when I wake up in the morning, the very first thing I do is good gratitude.
All right. It's like my instant reaction.
Thank you for the ability to live another amazing day. and can I contribute the maximum I can? And I just, it's like being excited to see what's going to, you know, there's infinite possibilities we're living in and just excitement for the day.
And a lot of the breakthroughs coming are, are across everything. So I have a $600 million venture fund in biotech called Bold Capital and Bold Longevity Growth.
B-O-L-D? B-O-L-D. And we're in our fourth fund now.
And so I see a lot of deals. And then I run something called the Longevity Platinum Trip.
Dr. Yanni Pisaltis and I scan through 500 companies and we pick 50.
And every year it's a new crop of 50 and we spend five days. I bring my abundance 360 members in who want to be part of it.
And we meet with the CEOs of all these companies and a lot of the people there to invest or just learn. and this year or last, 2024 was the first year we're starting to see instead of theory, actual therapeutics, actual things becoming available.
Um, I mean, I can jump into some of them. Yeah.
Yeah. No, I want to hear about some of them.
I mean, in my audience, this is right up there. Yeah.
So, uh, one of them that I love is a company called Immunus. Dr.
Hans Kirstead, this is his fifth company. He's had four increasingly bigger exits.
He's brilliant in stem cells. And what he identified was he created a iPSC-derived and an embryonic cell-derived stem cell that he can grow, and it puts out 450 discrete molecules and exosomes consistently.
Is this the Muse cell? It's not a Muse cell, but it is a... And I'll let him define it when he's ready to release it.
They just completed. So what they've done is that it was 440, actually 440 secretome that comes out of these cells.
He's been able to characterize it, consistently produce it and turn it into a drug. And the FDA has allowed him to use that as a drug.
So they just completed their phase one, two way study in which they were injecting IM twice a week for three months. And he's figuring out whether once a week or whatever the protocol will be.
But his first 18 patients were 50 to 75 years old. They were severe osteoarthritis, meaning they couldn't walk.
They were in pain. and he did this for a three-month period and here's the results.

Number one, these people who were effectively in bed rest, right? Yeah. Because of pain.
Because of the pain, because they couldn't walk, their skeletal muscle mass increased 6%. Without exercise.
Zero exercise. Wow.
Yeah. Amazing.
Number two, their pain reduced as much as 70%.

They were able to reverse their immune age by 30 years.

Wow.

And reduce their inflammatory markers by 50%.

And there were no other interventions.

Zero.

And it's consistent across everybody, no adverse reactions.

And so he's doing an expanded trial.

Mm-hmm. And there were no other interventions.
Zero. Fasting.
And it's consistent across everybody. No adverse reactions.
And so he's doing an expanded trial. I have signed up to be, you know, number one.
Of course you have. I mean, we're going to talk about me signing up as soon as this podcast is over.
So we're actually, we've cut a deal between him and Fountain Life. So Fountain Life is my diagnostic and therapeutic centers.
Tony Robbins and I, and Bill Kapp started this a couple years ago. We have four centers today in New York, uh, in Naples, where you started in Orlando and in Houston.
We're adding next year, LA, uh, Phoenix, Dallas, uh, and probably Miami. Uh, we've got a growth path for another 25.
Anyway, we're making this therapeutic available at no cost to our Fountain Life members as part of the expanded trial he's doing. So very, very excited about that.
Wow. Because our members are fully characterized.
Yeah. And we know they're healthy.
We know what shape they're in. Yeah.
All their data. Yeah.
You know, for folks that are not seemingly familiar with stem cells, and I don't want to put words in Peter's mouth, but these cells that you harvest either from Morton's jelly or, you know, these placentas cells, placentas, very often you can put these cells in specific type of media and they react to different ways.

You know, these secretomes you're talking about or exosomes are a reaction to, you know, the cell's media, what its environment is. And it's pumping these factors out based upon the environment it finds itself in.
Yeah, and you can get high molecular weight, high oleuronic acid. You can get growth factors.
So you can manipulate the cell to secrete these exosomes or secretomes that are specific to the outcome that you want. Maybe it's joint repair or it's collagen, elastin, and fibrin, or if it's inflammation reduction.
And again, I don't purport to be a stem cell scientist, but I'm fascinated by how they can take this one pluripotent cell and they can bathe it in different media. And, and it literally is like a chemical factory.
And depending on its environment, like a human being, it can have hundreds, if not thousands of different reactions. And then you can capture the by-product of that stem cells reaction and use it to treat specific conditions.
There's a lot coming in that realm. I'm the co-founder and vice chairman of a company called Cellularity, which I love.
Bob Hariri, who is an MD PhD, Tony Robbins and I and Bob Hariri wrote a book called Life Force. Yeah, Tony's everything.
Tony's a dear, dear friend. And we started a few companies together.
He's amazing. I have nothing but love for him.
But Bob Hariri would be a great guest. So Bob figured out early on that the placenta is really the 3D printer that manufactures the baby.
And at the end of child birth, most people, you know, you don't know this, but you're paying the hospital to incinerate and get rid of the placenta, which is like, if your baby was born with an extra set of lungs, kidney, heart, liver, would you like throw them away? And so, uh, one of the things that cellularity has is a division called, uh, for, uh, uh, first bank USA in which you can save your child's placenta. You decellularize it.
you pull out the stem cells, the natural killer cells, the T cells, the exosomes, and so forth, and it's cryopreserved so that your child, for the rest of its life, has a day zero set of its own stem cells forever. So both of my boys, who are now 13, when, when I go visit cellularity's headquarters, I go say hello to the, uh, nitrogen doer that has their stem cells in it.
That's awesome. But, you know, we talk about Wharton's jelly.
We talk about, uh, umbilical cord. The placental stem cells are probably the most powerful.
Really? And so, uh, cellularity is developing those products as well. Uh, and hopefully they'll become, uh, allowable.
We'll put those through fountain, uh, as well when they become approved in the U S when you say, when you say allowable, we can use them topically and intraarticularly. Right.
I mean, so, or, so no. So today, um, the FDA does not allow any stem cells really.
If they're your, if they're your stem cells, like from fat or, you know, and they're not manipulated, meaning they're not expanded. You're taking them out of your fat, which has a high population.
And your fat is actually one of your younger, is one of your, how do I put it this way? The stem cells in your fat are the youngest stem cells in your body. Your stem cells from your blood marrow are just recently manufactured, but fat stem cells can be as much as eight years younger.
You can pull it out and you can purify them and put them back in.

But that's fine. But the more interesting thing is, can you manipulate them and make them expand them there's nothing you can.
You can actually co-incubate your stem cells with young stem cells, like from a newborn, across a filter, but the exudate, the secretome of the young stem cells will rejuvenate your stem cells. Wow.
So there's a lot of work that Bob and others have done in that realm. I've seen some studies on this in, in plasma exchange, even Brian Johnson even did.
Well, I've done five therapeutic plasma exchanges, but not, yeah, yeah. I've done that.
Dr. Deshaun did it for me over at Next Health.
I did the therapeutic plasma exchange, which was amazing because, which is essentially where they take your plasma out. I took about two liters out.
It was quite a bit. Typically.
And then replaced that with sterile albumin. I was very tired that night, but it actually worked out because I did it in LA and then I had a 15 hour flight, nonstop flight to Dubai and I was on Emirates.
So I just laid the seat flat and crashed. But the next day I woke up with like a level of clarity.
I don't recall having in probably 10 years. You know, I, I, um, I just felt cognizant, clear, awake, focused, just switched on.
And, and therapeutic plasma exchange or TPE, uh, we we have that available at our Fountain Life centers as well.

You do at Fountain Life. Okay, amazing.

All of your centers do that?

Our headquarters right now in Orlando,

we will be rolling it out to all the centers in the year ahead.

That's amazing.

And it really is, you're hooked up to a machine.

It takes about two hours.

You pull out about two to two and a half liters of blood, about half of your blood supply. Well, of all the blood, it spins out the red cells and white cells and platelets and it puts them over here.
It pulls out your plasma, which I think of it as my oil change, right? And then it gives you fresh saline and plasma, puts the cells back in and returns that to your body. So you're pulling out all the inflammatory factors.
Now for a number of diseases like neuro related diseases, it's life savings. For others, and I think Dr.
Kiproff who developed this sees like a reversal of three to five years on your epigenetic age, but it really matters. How do you feel at the end of the day? No, how do you feel? And I think that our plasma is, is a, you know, repository for a lot of the junk, mold spores, mycotoxins, metals, viral pathogens, um, cytokines, there are all kinds of things that are floating around in the plasma, um, that are not being evacuated.
Another, another company that you and I are both fans of, Xterra Medical, right, is fabulous, right? So here's a technology coming out of DARPA years ago and developed jointly in Sweden in this blood filtration system that has got 40 square meters, about the size of a tennis court worth of this material called a glycocalyx that filters out all viruses, all bacteria, all circulating cancer cells. I mean, amazing.
And there's a very real phenomenon people don't talk about called immunoexhaustion, if you've heard of that term. I can understand what it means.
As we grow older, we have been burdened with all of these different viral infections. Besides COVID, maybe you have Epstein-Barr virus, maybe you have cytomegalovirus, maybe you have a multitude of other viruses that they're not active.
They're in your body. And on occasion when you get run down or stressed, they start coming out and your immune system needs to fight all these viruses and cancer.
And it's the same innate immune system, your natural killer cells. And so it can become overloaded.
It can become exhausted. Yes.
And so one of the things I like about Xthera Medical, and we're rolling that out through Fountain as well. I saw that.
Yeah, we're Fountain, you get a 15K discount on the blood filler filter systems if you're a Fountain member, which I'm proud of. It's the ability to filter out all of these pathogens and give your immune system a deep breath.
Yeah. A chance to, okay, now we're going after you.
Yeah, yeah. You're taking it from having to fight on so many different fronts and having to fight on fewer fronts.
And I think you glossed over something, but I want to drill in. So this filter, think of a dialysis machine, right? Yes, exactly.
I mean, that's probably the closest thing for people to, you know, analyze what it is. And you pull the blood out and it runs through this filtration system and they have heparin binding sites, which vary.
When he says the endocalyx, the glycocalyx, what he means is it's mimicking sort of the lining of the artery, the wall of your vessels. Yes, the inside of your blood vessels.
Which is where these pathogens like to go. And so they see this surface as the surface area of your blood vessels, and they attach to it, and they can be taken out of the body.
And what I found fascinating, and I'm going to have their lead oncologist on the podcast. Is is that dr mink chella yeah dr chella

he's brilliant oh he's so brilliant and and he's so well spoken and um i've done a number of uh zoom calls with him and i i like he's a very giving human being very brilliant but also very well spoken so that you know he's not just talking from phd to phd he's he really has a way of fundamentally helping you understand.

And obviously he's an oncologist.

So that, that helps. But how he was explaining this to me, which made perfect sense was, you know, along the lines of this immuno exhaustion where, you know, all of us at some point in our life have had circulating cancer cells.
Now immune system has taken care of them. People need to understand your body is always producing cancers.
It is, you know, there's something called the Hayflick limit that a cell divides 50 times and then should have the decency to die. But sometimes it becomes an inflammatory cell, a grouchy old man cell, a senile cell.
Senescent, yeah. Other times it becomes a cancer.
And when that happens, your innate immune system, your NK natural killer cells, typically detect it and kill it. But sometimes it evades those and they become a cancer.
And all cancerous cells were at one time a healthy cell. I mean, they became metabolically sick.
And the idea is if you can get these metabolically sick cells out of the bloodstream or circulating tumor cells, and now the immune system, immune system has less to do and it has more time and more strength to focus on whether it's a nodular cancer or something else that's, that in the body. And I really found that fascinating.
And also found it fascinating from the risk standpoint, because things like chemotherapeutics and high dose radiation or, you know, aggressive surgical resection, I mean, those have real consequences. They may be necessary, but they have very severe consequences and may not work.

Yeah. Whereas, you know, a blood filtration, um, if your downside is that it doesn't work, I mean, your upside is at least that it's not very likely.
And by the way, it's probably going to help you if not on the directly in the cancer, it will help you on getting rid of your viral loads. It's about really giving your immune system a chance to take a breath and defend you.

You know, one of the things I'm very proud of, getting rid of your viral loads it's about really giving your immune system a chance to take a

breath and and defend you um you know one of the things i'm very proud of i'd like to mention

is our health span prize so um yeah this is fast yeah so uh folks who don't know me from the x

prize perspective uh 30 years ago hard to believe i launched our first uh 10 million dollar prize So I offered up $10 million for the first person who could build a private spaceship, go to 100 kilometers, land, and make the trip again with the same ship within two weeks. This was way before SpaceX and Blue Origin, and space was not a common conversation.
And the idea of commercial space didn't exist. an amazing woman, Anousa Ansari, who's now the CEO, I serve as chairman of the XPRIZE, put up the 10 million for a family.
I put up the first, you know, I don't know, I hadn't had that much money back then, the first hundred thousand or so. And it worked.
And on the heels of the XPRIZE getting one, the first one in 2004, I was able to attract Elon Musk on my board, Larry Page, James Cameron. It's like, you know, everybody loves a winner.
And so we turned the foundation into an organization that was launching large scale global competitions. And we're saying, I don't care where you went to school, what you've ever done.
If you demonstrate and solve this problem, you win the money. So we've launched 30 prizes, about $550 million of competitions driving close to 8 billion in R&D.
And this is not like a Nobel prize that you award somebody for something done 30 years ago or 10 years ago. This is a prize where we say, okay, the first person to do this, it was modeled after the prize that Lindbergh won flying from New York to Paris.

It was a $25,000 prize offered for the first person to fly. Nine teams made the effort.
Lindbergh won. Wow.
I did not know that. And so we've launched 30 prizes, mapping the ocean floor, pulling water out of the atmosphere.
Let's see, five years ago, I got Elon to fund a hundred million dollar carbon extraction prize, which will be awarded this coming April for pulling CO2 out of the atmosphere and out of the oceans at mass. It's an amazing prize.
Wow. I'd love to know what the hell that technology works.
Yeah. Well, you'll find out.
Okay. In like January of 2020, Elon became like the most wealthiest person on the planet.
And he was getting a lot of crap for not being philanthropic. So I texted him.
I said, why don't you fund an X Prize? He said, what do you have in mind? I said, how about one around carbon? He said, how much? He said, 100 million. He said, he wrote back, sure.
I love Elon Musk. And then a month later, we were assigned, and he put up the money.
So for the last five years, I was like, there's got to be a prize in the longevity space. And we ended up designing a prize.
You know, folks like George Church and David Sinclair, Ray Kurzweil. I'm blanking on his name.
Aubrey de Grey, who really was the first person to prompt me on this. And we designed this prize.
And I raised $141 million. And this is a prize that was launched a year ago.
And to win this, you need to demonstrate a therapeutic they could deliver in one year. So imagine someone comes to you.
I'm going to give you, Gary, for a year, we're going to give you this therapy. And the impact is going to be that your cognitive, immune, and muscle will be 20 years younger.
Wow. Right? So we're not looking at your epigenetic age or anything like that.
What we're looking at is how do you feel? Do you have the ability to build muscle, maintain muscle as strong and capable as you did 20 years earlier? Do you have the cognitive span of memory? Do you have the immune function to mount a reaction to a, you know, and how are you measuring that? Just there's a marker. There's a whole, no, we're doing it.
We'll do an immune challenge. We'll give you a, you know, a vaccine and how well do you mount a response to that? And it's functional.

It's using functional endpoints instead of just markers.

And so I'm really excited about it

because I think that's what really matters.

Yeah, I think so too.

Do you feel younger?

Are you functioning in a younger state versus,

oh, look at my printout.

Who gives a shit about your printout

if you don't feel that, right?

So we have, and here's the punchline. A year later, we have 460 teams competing for that HealthSpan prize.
460 teams, and they're all trying to reduce the age. And how are you measuring that? Telomere is like an age test? So again, it's reversing the functional losses of an immune cognition and muscle so that, you know, you've got the capabilities you had 20 years ago.

And amazing companies. And so I'm seeing all of these companies and my job is to – So fascinating.
Yeah, I take myself off the judging board and off of all of that so that I can help promote and support them and not be, you know, in a problem of promoting one over the other. But like yesterday, it was a few days ago, this one company that will go from a skin cell, regrow a pluripotent stem cell for you.
And then let's get put aside the ethics here,

but create a clone of you, right, on a cellular level.

So here's a, and grow that embryonic clone to 28 weeks of Gary

and maybe we'll produce a thousand of those clones

and way before the brain is developed and such.

In fact, they have a genetic change they can make

so that the head of the clone doesn't develop.

But what we can do now is pull out of your clone

day zero hemophobic stem cells.

That are an exact copy of my hemophobic stem cells.

Of what they were when you were young.

Wow.

There's amazing stuff coming.

Wow. So I talk about this idea of a longevity mindset.
Yeah. And I have a whole, you know, again, a chapter in the book about this, that your mindset is the most important thing.
And if you do the work, understand what's going on, right, and you realize, oh, my my God, there is a health span revolution coming and it's this decade. And I want to see, I want to be there.
I want to be ready for it. I'm going to keep myself in the best health I can.
Right. I don't want to miss it.
Um, and that's, there's gotta be some reason why you don't dig into the chocolate cake. Yeah.
Why you don't like just sleep through your alarm and forget the gym, why you don't get your eight hours of sleep. And that reason for me is I want to keep myself, first of all, I love being in great shape in terms of feeling strong, thinking clearly, ability to act, having the energy to run circles around my 20-something year old staff members.
But ultimately, it's about being in the best health I can in order to

intercept these breakthroughs. And when you say intercept these breakthroughs, a lot of these

you're tangentially involved in through? Through the XPRIZE, through my venture fund,

through the companies I advise, and so forth, yeah. So who's looking at the XPRIZE winner

in the money. So we'll be announcing the first 40 companies that will get a quarter million each.
We'll be announcing those. It'll be worth keeping your eye out for who those 40 are.
Yeah. Then about a year, 18 months later, we'll be announcing 10, they'll get a million dollars each.
All the teams are still in the running. And then the remaining 80 million, 81 million is up for grabs for whomever can reverse it.
You have to reverse a minimum of 10 years. The goal is 20.
Do you want to know why it's101 million, not $100 million? Yeah, yeah. I'm curious about that.
So the first donor, an amazing man, a guy named Chip Wilson. I don't know if you know Chip.
He's the founder of Lululemon. Okay.
And he has a muscular dystrophy called FSHD. I've heard about this.
And we're on the phone and he's become a dear friend. I love him.
He's a beautiful human being. And he's like, okay, I don't want to put all the money in, but I'll put a chunk in.

But he says, how much is Elon's prize again for carbon?

I said, it's a hundred million.

And he goes, can we make ours a hundred and one million?

And I said, okay.

Because I want to attract people to Austin, not the carbon.

Yeah.

Because I said, okay, if you put the extra million in.

So he increased his donation to 36 million. And we also have an additional $10 million bonus prize for a breakthrough in FSHD.
And I'm very blessed. There's an incredible woman, Jamie Justice, who's a PhD who runs this competition.
I just raised the, and handed her a set of rules and she's, she's running this thing and it's, it's doing amazing. So proud.
Yeah. And, um, so does your, does your book go into some of these topics or? Yeah.
So I made this book. So Tony Robbins and I wrote this book called Life Forces, 700 pages, New York times bestseller.
I made my way through an incredible book. I've actually put it on my top 10 must reads.
So it was New York Times bestseller for two months, but it's 700 pages. It's hard for someone to read 700 pages.
So I wrote this book as a very digestible how-to, And you can pick up any piece of it.

So yes, it's like all the details,

everything I do and what I've researched

and what works in sleep and exercise and mindset

and not dying from something stupid,

which is what-

I love that.

I mean, let me take a second and talk about that.

But then it does go into the XPRIZE

and where these sciences are going.

There's a chapter called, you know, Don't Die from Something Stupid. What does that mean? So, you know this, our body is really great at hiding disease.
You know, I tell you in a room of a thousand or 10,000 people, I'll say, how many of you here are absolutely sure there's nothing going on inside your body you need to know about?

You know, raise your hand. And, and no one does unless they've just gone through a, you know, a set of full scans.
Like a Fountain Life. Yeah.
A Fountain Life diagnostic. So, uh, four years ago, Tony, uh, uh, Bob Hariri and I backing from, uh, from Mark Benioff and others, we built this company called fountain life these are 10 000 square foot facilities um we have four today four more next year a road a mode map to get to probably about 30 35 around the world and you come in you spend about five hours with us and we digitize you.
It's everything knowable about you. Full body MRI, brain, brain vasculature, coronary CT with an AI overlay, low dose lung CT, DEXA scan, retinal scan, skin scan, full genome, microbiome, metabolome, full blood workup.
Again, everything knowable about you. And all of that data then gets digested by our AI system.
It's all functional medicine based. The entire company is functional medicine.
We have an amazing chief medical officer, Dr. Helen Messier, who teaches functional medicine.
And we have a fountain university. Our doctors, our nurses, our health coaches, everybody's functional medicine and the AI digest it.

And there, there are two things we're trying to, you come in for, to answer two questions.

Is there anything going on inside your body right now you need to know about?

No.

And what's likely to happen to you and how do we prevent it from happening?

Wow.

Right.

I mean, that's, that's what you should know. So, um, here's the results in our first 5,000 members, 2%, everybody coming in is seemingly healthy 2% of a cancer they don't know about.
Wow. Right.
I mean, think about it. You know, someone who went to the hospital, went to the doctor's office with a pain in their side and was like, sorry to tell you this, but you've got stage three or stage four.
Right. And it didn't happen that morning.
Right. It's been going on for some time.
And people go, I don't want to know. I was saying, bullshit, of course you want to know.
Yeah. You're going to find out eventually.
You want to know now when you do something about it or when it's too late. Yeah, you are going to find out eventually.
So your body is great at hiding that. 70% of all cardiac disease has no precedence, no shortness of breath, no pain.
Even your calcium score doesn't matter, right? Your calcium score, calcified plaque, unless it's blocking the coronary artery that feeds the heart muscle, sugar, and oxygen, unless it's blocking it, in which case, yeah, you want to see that. Calcified plaque on the side of a coronary artery is stable.
What we've discovered in the last few years, it's something called the soft plaque. Yeah.
That's on the wall of the arteries, right? So there's a special AI overlay called Clearly. James Min, Dr.
James Min, who invented this, brilliant. And it's the soft plaque that in the middle of the night can break off and block your coronary artery and you don't wake up.
And so we can detect through this AI overlay your soft plaque. Most of the cancers that kill people are not cancers we screen for because we screen for breast

and prostate and intestinal cancers,

but we don't screen for glioblastomas, pancreatic cancers.

And so we find these things.

We've saved hundreds of people's lives.

I get thank you notes all the time.

God bless you.

Thank you for saving my life over and over again.

And one of the things that's important is it's not any one thing. It's multimodal, right? It's the imaging plus the blood chemistries, plus the grail test, plus everything, all this stuff comes together.
So that's what the chapter on that is. It's not cheap.
It's $19,500, but it comes with a medical team for the entire year with a physician, a nurse, health coach, a dietitian. We have just rolled out a $6,500 product called Core, which is through companies for their employees.
And that's a scaled down version of what you're talking about. It's all with the same testing.
Yeah. It's just not with the year round medical team.
The humans still cost a bunch. Yeah.
They'll be demonetized and democratized by AI in the years ahead. And you plan to bring in AI to overlay a lot of this and make the diagnostics easier.
So then maybe it's on my phone. I have all of my data.
You do. And on my phone is an AI we call Zora that I can query, like, tell me what you saw in my images.

Tell me what correlation you have in my blood chemistries and my genetics.

You can ask it.

So that's already functional.

It's all it's here.

It exists.

A fountain life client could put that on their phone, get their diagnostics done, and then start asking questions.

Yes.

Your doctor will clue you in. And the most important thing is not to get overwhelmed.
on their phone, get their diagnostics done, and then start asking questions. Yes, your doctor

will clue you in. And the most important thing is not to get overwhelmed, to give you an actual plan and to have a nurse, a physician, a health coach, a dietician with you through the year to then to get you through and improve.
And by the way, this is never a one and done. Right.

It is, I do this, I've done this every year, originally through human longevity. And now for the last four and a half years with, with fountain, um, because eventually I'll find something and I'll say, thank you.
Yeah. And you'll find it early enough.
Um, and that's what I talk about a lot is the early detection, the artificial intelligence and the big data. Um, because one of the we realized in the mortality space was the big data was actually more predictive than any kind of randomized clinical trial or a lot of the scientific periodical data that we were getting.
You know, you could look at large populace of data, 371 million lives in the mortality database that we used to have access to. And we would see things like what you were talking about earlier.
Well, there was elevated LDL cholesterol in this entire populace, but the ones that had the lower triglycerides actually had no impact on mortality. As triglycerides rose, it actually made the LDL more dangerous, and we had an increase in all-cause mortality., you know, it's not as linear as we think, just like you were, you were, you were saying the, the, the fascination that I have with AI are these 700 trillion independent variables.
You talk about the number of methylation. And no human can understand all that, but AI can take it all in, process it and help you.
And then eventually we'll have our AI coaches, which say, Hey, Gary, don't take the elevator. There's stairs around the corner.
Take that. Like, you know, you'll give permission to your AI to watch everything you do, see what you're eating, listen to your, you know, your, your conversations, your emails, and it will advise you.
And so you can turn on health coach. And the other is you know i'm wearing a uh where is it my cgm i'm wearing my aura ring and my apple watch but i mean i'm i'm invest i'm investing in he's got data i mean i'm investing in all these sensor companies because eventually all of this data is going to be uploaded to my ai and uploaded to the robot in my kitchen that will cook the perfect food that my body needs that next hour.
Hey guys, let's talk about meat for a minute. Did you know that 96% of the beef sold in stores is not grass fed? That's right.
Most beef comes from cows fed a grain-based diet in feedlots, which isn't even healthy for you or the cow. And even if a label says grass-fed, that doesn't always mean what you think.
It means a cow spent at least 50% of its life on grass. So now if you're ready to eat a real nutrient-dense meat that was raised on a pasture, then let me introduce you to Parker Pastures.
I love this place. The story of Parker Pastures is as inspiring as it is heartwarming.
Chloe Parker, just 19 years old, took over the family business when her mom was diagnosed with cancer. Instead of backing away, Chloe stepped up to lead and turned an overwhelming challenge into a calling.
Chloe says it best, in honor of my mom and for the health of all, I guarantee Parker Pastures meat will always be flavorful, nutrient-dense, and healing for both you and the land. You can order grass-fed and grass-finished beef, lamb, bison, as well as pasture-raised pork and chicken to be delivered straight to your door next week.
She delivers to all 50 states. So why settle for mystery meat from the store when you can eat meat that nourishes your body and restores the earth? Visit parkerpastures.com today and you'll get 25 bucks off your order.
That's parkerpastures.com and get $25 off your first order. Now let's get back to the Ultimate Human Podcast.
I mean, that's sort of the Brian Johnson method, right? I mean, he's almost taken himself out of any of the decisions, the decision processes and all of his supplements fight for the life and his caloric intake, you know, is, is prescribed, you know, right down to the macros and the micros. And his erection as well.
His erection as well. He does talk about that a lot.
Um, but, um, you know, you're, you're also known for taking, um, up to 75 supplements in a, in, in, in a day. Um, I think I'm up to 80 now.
Are you, I'm, I'm, I'm not far behind you by the way. And sometimes I'm afraid to even tell people all the stuff that I'm taking because they'll think, wow.
Um, but how did you formulate, you don't have to be hyper specific, but how'd you formulate this supplement regimen? You know, I used to have people ask me, please tell me. And I had this five page document and this 10 page document.
And I said, screw it. And so the whole chapter in the book of exactly what I take and why.
And I do all of this in consultation with my Fountain Life medical team, right? I'm tested at least quarterly, if not more frequently than that, because I care. Data is power.
I agree with you. If you don't have data, you don't have nothing to take action on.
And by the way, I talk about in the book, a lot of other lower cost programs that you can do. There's LifeForce, which is around blood testing and supplements.
There is PreNovo, which is only the MRI without the follow-up. So, uh, the follow-up.
And so there's

a lot of different things and I list them all, um, so that people have alternatives. Uh, but the way I think about it, uh, there was a paper published in cell that talked about the hallmarks of aging and they're originally like nine.
Now they're like 12. And so when people said, why do we age? There's a number of very specific elements like stem cell exhaustion.
I should just say, first of all, our bodies were never designed to live past age 30. Hate to say it, right? If you think about it, 200,000 years ago, you were in puberty at age 12.
By 13, you were pregnant before birth control was around. By the time you were 26, 27, 28, you were a grandparent.
And before McDonald's and Whole Foods was here, if you wanted to perpetuate the species and pass on your genes, you didn't want the grandparent stealing food from the grandchildren's mouths. And so lifespan was like 30 years.
And so if we look at this, it's just, it is in a lot of things. And I talk about this evolutionary rationale and reason from earlier on.
Our muscle mass starts decreasing after the age of 30, our hormone levels, right? Our thymus is gone. Our muscles begin to atrophy.
All of these things. And you can and should fight it.
And I do with all the efforts and all of that. Exercise.
All those things. When you go back to the hallmarks of aging, right? Our stem cell population.
So stem cell exhaustion is one of them. The end caps of our DNA, our telomeres, there is mitochondrial degradation that occurs.
There's all of these, and I list all 12 hallmarks of aging. And then the way I built my supplements is looking at which are the supplements that can impact each of those 12 hallmarks.
And there's great science behind each of them. So like resveratrol, DHEA.
Well, you know, and NAD. So NAD, nicotinamide, adenine dinucleotide, which is the power currency in our cells.
David Sinclair did a lot of incredible work on this and kudos to him. You know, we have these seven sirtuins, these proteins.
And the sirtuins have two functions in your cells. One function is that they are correcting DNA mutation that we accumulate as we get older.
The other function is they keep- Howi... How do they correct a DNA mutation? So they repair it? No, the sirtuins are part of the DNA repair system, but they also maintain your epigenetic situation.
So what do I mean by that? When you're born, when you're 20, when you're 50, when you're a hundred, you have the same exact genome, right? 3.2 billion letters from mom and from dad, your software doesn't change. So why do you look different at, at 80 or a hundred? Why don't you have the six pack you had when you were 18? It's not the software you're running.
It's what genes are on and what genes are off.

It's your epigenome.

And the control of what genes should be on and what genes should be off is driven by

these seven sirtuins.

And as we get older, the sirtuins are having to correct DNA damage and keep us from having epigenetic drift. And they are powered by something called NAD+.
If they don't have enough NAD, and the NAD in your cells drops by over 50% as you age. And so when David and others talk about NMN or NR as a supplement,

that is the precursor to NAD.

Yeah, you can't really take the NAD orally.

I guess you could do it injectively.

You can, but it doesn't even get into the cell that way.

You want a precursor like NMN or NR that crosses the cell surface

and gets converted to NAD.

So the supplements and meds I take are to address those hallmarks of aging. And the science is there.
I present it, but I'm very clear. Listen, this is what I do.
This is why I do it. Do the research yourself, find a physician and start incrementally.
My mom still says to me, Peter, how are you sure those things all don't interact

with each other in the wrong way?

So mom, I don't know.

I don't know.

Honestly, I don't know.

I feel great though.

Yeah.

Yeah.

I mean, that's ultimately, that is ultimately,

you know, do you look good?

Are you thinking clearly?

Are you moving well?

Are you enjoying life? You know, one of the best pro longevity things I've ever done is having kids at 50. Wow.
All right. So two boys at 50, they're, they're 13 now.
And a lot, you know, when I go to sleep every night, one of the things I do as a part of my practice is what are my three favorite memories from the day? What am I for and almost always it's around them yeah it's not some deal i closed or some investment i made yeah that's so cool i feel the exact same way around family and this goes back to the whole idea about the importance of community and not being in isolation you know we knew in the mortality space that if you wanted to cut a human being's life expectancy in half, and I mean at any age, put them in isolation, and it would literally cut their life expectancy in half. At whatever age they are, you could have it in isolation, and I think that, you know, again, I don't purport to be a mental health expert by any means, but I think there's an argument to be made that the amount of social media that we consume the amount of artificial um relationships and stimulus that i'm scared shitless for my 13 year olds about ai girlfriends them in isolation right right i mean i don't consider you having access to your phone um and the media on that phone to be out of isolation i would actually consider that to be in isolation and so um you know with with life expectancy the united states is going backwards it's actually tanking um for a whole host of reasons but not the least of which i believe is we are losing touch with the basics of humanity you know um mother nature you don't touch the surface of the earth.
We don't get much sunlight. We don't ground.
We don't walk in nature. We, we, we don't have a lot of human interaction.
We have a lot more of an electronic, you know, interaction. And I, I believe that this is a form of isolation.
You know, it's, it's, it's removing again, back to the blue zones. I mean, mom mom there were no such thing as assisted care living facilities grandma and grandpa moved back in with the kids until the day they died and maybe her only role was to go get vegetables for dinner you know um but uh you're so so right i mean human touch you know i have my favorite hug dealer hug dealer t-shirt and which i'm not sure if it's socially acceptable now to have that, but it's like, yeah, just, I mean, it's like, it's like just to give someone a hug and breathe deep with them and just say, thank you for being in my life.
It's a, it's a, it's a beautiful thing. These are the fundamental elements of life.

Well, I am really excited that our paths cross. I don't think that you and I have written our last chapter.
I think we're about to write our first chapter. We're an introduction, my friend.
Our first chapter together. Where do people that haven't interacted with you, where can they find you? Where can they find out more about you? So longevityguidebook.com will give you a whole bunch of resources and a deep discount on the book.
Please use this book, even if you just pick one chapter to focus on. My goal is to get this information out there.
You have control over every aspect of your health. Be the CEO of, be the CEO of your own health.
It's so truly important. You can go to FountainLife, fountainlife.com to learn more about those offerings.
And I hope people will take advantage of it. My podcast is called Moonshots.
Moonshots, okay. Yeah.
And I've had the pleasure of interviewing Elon a couple of times and Eric Schmidt, a whole bunch of AI experts, a number of folks in the longevity space. I'm focused on who's taking the biggest shots in the universe, who's open for impacting the world at a tremendous level.
Yeah. And I need to have you on my Moonshots podcast.
Yeah, I'm happy to be on there. I mean, I'd be honored to be on there.
Yeah, thank you. Thank you.
Yeah. I'll take that.
You shoot it out in LA? I shoot it out in LA, yeah. Okay.
A new studio I built out in Santa Monica. Okay.
Diamandis.com, I put out two blogs a week. My job at this point in my life is to inspire.
So I talk about something called a massive transformative purpose, an MTP. Right? Mark Twain said there are two important days in your life, the day that you were born and the day that you found out why, right? Really beautiful.
And so at Singularity and at Abundance 360, which is my CEO level forum,

I teach creating a massive transformative purpose. And it's something that wakes you up in the

morning, keeps you going through the night. It's what longevity connects with, right? Having a purpose and a future bigger than your past.
And my massive transformative purpose is to inspire and guide entrepreneurs to create a hopeful, compelling, and abundant future for humanity. So my job through the XPRIZE, through Singularity, through all of this is how to help entrepreneurs go big and bold in the world.
Yeah, that is amazing, man. Especially in the area of longevity.
Especially, yeah. Bio-optimization.
Yeah, that's fantastic. Well, I want to get every podcast down by asking my guests the same question.
There's no right or wrong answer to this question. And that is, what does it mean to you to be an ultimate human? To be, so to be my ultimate self is to give, put it all out, leave nothing in reserve.
And it's being true to myself, authentic to myself. It is playing all out on my mission and purpose in life.
It's being a good person. It's knowing that I have left this planet better than I came into it.
I mean, those are the elements. And to make that happen, I need to have the best physical health I have.
Yes. Right? Because I'm going 24-7 with my eight hours of sleep in there.

Yeah. And I'm just, I feel blessed to be alive.
This is the most magical time ever in human history. I do too.
Gosh, I do too. Right? One of my favorite slides I use in presentations is a slide that the title is, Our Ancestors Would View Us as Gods.
Hmm. Let me just reflect on that for a second.
Yeah. The things that we did this morning is, you know, we're omniscient, we're omnipotent, we're omnipresent.
We are creating new life forms in AI. I mean, it's amazing the life we live in.
Yeah, it really is. Yeah.
Well, Peter, I cannot thank you enough for coming on. I mean, this is a true honor to have you on here you i'm excited to be on on your show too i will put everything that he discussed in the show notes

below guys including a link to his book check dr diamantes out um absolute mentor of mine

and as always guys it's just science