123. Dr. Peter Diamandis: The Future of Health with Stem Cells, Blood Filtration, & AI

Speaker 1 Our bodies were never designed to live past age 30. Our muscle mass starts decreasing after the age of 30.
Our hormone levels, our muscles begin to atrophy.

Speaker 2 I don't think that the majority of Americans even think of muscle as an organ. They don't think of it about it being our metabolic currency.

Speaker 1 There's a direct correlation between the amount of skeletal muscle you have and your longevity. Fundamentally, it comes back down to diet, sleep, exercise, and mindset.

Speaker 1 And the way that you do those things is to wrap routine around them.

Speaker 2 Sort of the discipline over motivation. We've actually gotten away from the basics, the basics that you just talked about.

Speaker 1 Most people are healthy until 63. And our goal here is, can we at least move your health span up to that 80-year mark? This is the decade of a health span revolution.

Speaker 1 And the biggest impact is going to be coming from AI.

Speaker 2 When you have artificial intelligence that can take 700 trillion independent variables and create an actionable result.

Speaker 1 And no human can understand all that. But AI can take it it all in, process it, and help you.
And ultimately, it's about being in the best health I can in order to intercept these breakthroughs.

Speaker 2 We're both on the same journey, you know, this childlike fascination with longevity. What are just the basic building blocks of somebody who wants to live a long, healthy life?

Speaker 1 Yeah, one of the best pro-longevity things I've ever done is having

Speaker 2 Hey guys, welcome back to the Ultimate Human podcast. I'm your host, human biologist, Gary Breca, where we go down the road of everything: anti-aging, biohacking, longevity, and everything in between.

Speaker 2 And as you just heard, today's guest is probably one of the most iconic guests that we've had on the podcast in a long time, if not the most iconic guest. I'm an enormous fan of his.

Speaker 2 We were actually just fanboying over each other. And

Speaker 2 he's like, I'm a fan of yours.

Speaker 1 I'm like, well, I'm actually a fan of yours.

Speaker 1 I've been following you for longer.

Speaker 2 But welcome to the podcast, Dr. Peter Diamantis.

Speaker 1 My pleasure, guy. It's amazing to be here with you in beautiful Miami and in your incredible environment here.
You, you walk the talk, you live it, and so proud of what you built.

Speaker 2 Thank you so much. I mean, that is a very high compliment coming from someone like yourself.

Speaker 2 You know, I've actually been following your trajectory from, you know, from afar for several years now i kind of find it fascinating how i think you're you're one of those rare kind of left brain right brain kind of entrepreneurs um that's able to get deeply embedded in the science but also see how it can have a practical application to humanity and we're both on the same journey you know there's this this fascination this childlike fascination with longevity and and um the the extension of life and you know i want to go down that road with you um a little bit because, you know, as I've traveled around the world and met with some of the brightest minds and seen all the biohacking equipment in the world, and we're going to talk about some of the things that I think are fascinating both of us in the space of longevity.

Speaker 2 The one thing that seems to stick with me is that

Speaker 2 we need to get back to the basics

Speaker 2 and then advance to the fancy stuff.

Speaker 2 And what is your feeling on that? I mean, what are just the basic building blocks of somebody who wants to live a long, healthy life?

Speaker 1 I think about that a lot, and I'm clear that

Speaker 1 fundamentally, there are a whole slew of things that cost you nothing

Speaker 1 that have a huge impact right now. A lot of people know me as a technologist or investor in biotech or AI and building companies in that field.

Speaker 1 But what I really want to gift in this conversation with you is like what you can do right now that moves the needle for you. And it's not spending hundreds of thousands or millions of dollars.

Speaker 1 You can do that as well.

Speaker 1 But fundamentally, it comes back down to diet, sleep, exercise, and mindset. Yes.
Those are the elements that if you don't have those dialed in, you know, forget about the other stuff. Right.

Speaker 1 Let's dial those in. And, you know, we're here discussing my latest book, Longevity Guidebook, how to go, you know, how to slow stop reverse aging and not die from something stupid.

Speaker 2 I love that, not die from something stupid.

Speaker 1 It's important because I think that should have been the title of the book. It's such a great dialogue.
It really is. Thank you.
But, you know, it's

Speaker 1 there. So there's a chapter on diet, a chapter on sleep, a chapter on exercise, a chapter on mindset, and importantly, this time, a chapter on routines.

Speaker 1 Because I think the single greatest innovation I've, I'm 63 right now. I feel like I'm in the best health I've ever been.

Speaker 2 You look amazing, by the way. You're a lot more jacked than you look at.

Speaker 1 I added 10 pounds of muscle last year. Really? I went down, you know, muscle is your longevity organ and I went full on.

Speaker 2 Did you do full statin gene therapy?

Speaker 1 No, no, no. It was working out in the gym with weights every day, five days a week.
It was

Speaker 1 cretin. It was 150 grams because I weigh 150 pounds of protein every day.
And it was doing the work. Yeah.
It was doing the work.

Speaker 1 Now, doesn't mean, and we can talk about this, some amazing biotechnology coming in the future that will make it a lot easier.

Speaker 1 My job now is to maintain that, but lots of studies around the world show that there's a direct correlation between the amount of muscle mass, skeletal muscle you have, and your longevity.

Speaker 1 So, again, the chapter on

Speaker 1 diet, a chapter on sleep, a chapter on muscle, a chapter on mindset.

Speaker 1 Those are things that we should be doing now. And the way that you do those those things is to wrap routine around them.
Yes. You know, what is routine?

Speaker 1 It's not negotiating with yourself over and over again. Right.
Right. It's like waking up in the morning and like, this is who I am.

Speaker 2 Sort of the discipline over motivation.

Speaker 1 It is discipline over. That's a good point, a good way to put it.

Speaker 1 And it's like, it's, it's creating that person. who you want to be and who you are.
So it's like, I am the person who gets up at this time and does these things.

Speaker 1 And when you identify with that,

Speaker 1 it helps you not negotiate and say, well, you know, I want to stay in the cuddly bed a little bit longer or, you know, that dessert, I can rationalize eating that dessert right now.

Speaker 2 Yeah. You know, it's, it's, I, I talk about this a lot too.
You know, I,

Speaker 2 um, you know, in some of my workshops, we, we, I, I talk to a lot of folks and it's interesting how people think that self-care is very selfish, right? So, um, you know, I've developed this

Speaker 2 philosophy that, um, and I apply it every day, that the first 90 minutes of every day, um, belongs to me.

Speaker 2 Yes, your golden hour, yeah, it's just my, it's my golden hour, and it doesn't belong to my spouse, or my employees, or my clients, or my partners, or, or, or, or even to, you know, my podcast.

Speaker 2 It belongs only to me. And it sounds very selfish, but then I just give the rest of my day away, right? I'm very intentional with my children, my spouse, with my team,

Speaker 2 you know, with the clients. I'm able to be very present with them.
And for me, it's been an absolute game changer. And then I put some non-negotiables, simple non-negotiables into my schedule,

Speaker 2 you know, where I schedule all of my meetings and travel around sleep and exercise. Yes.

Speaker 2 And I'm not the fittest person in the world. And I get some nights where I don't get good sleep, but by and large, you know, my sleep scores are 96% plus.

Speaker 2 And

Speaker 2 I don't go a day without doing some kind of physical exercise. It has had the most dramatic change

Speaker 2 on the amount of enjoyment that I get out of doing what I do.

Speaker 1 I agree with you 100%.

Speaker 1 So I have the same philosophy. I'm up typically at 5.30 in the morning.

Speaker 1 And that starts by being in bed by 9.30 the night before.

Speaker 1 So I'm at my abundance summit. I've got 600 CEOs, people from around the world.
They're partying hearty and they watch me. Peter, come on.
Sorry, it's bedtime. Yeah.

Speaker 1 So I'm out of my own events at 9.30, you know,

Speaker 1 at 9 to be in bed by 9.30.

Speaker 1 And then when I get up at 5.30, that first, really, it's the first 90 minutes. It is my, my golden time.
And

Speaker 1 it is, I love writing during that time. So I'm writing every day.
I've got three books in production. This is the first of the three.
I'm very excited about that. And thank you.
And,

Speaker 1 you know, I put out two blogs a week, but I'm in the gym.

Speaker 1 doing red light therapy, meditating. And

Speaker 1 it's that period of time that, like you said, it's selfish. It's mine.

Speaker 1 And it allows me to perform at a much higher level. Now, to be clear, I wasn't always that way.

Speaker 1 Right. And it doesn't mean you go from zero to infinity.
I got there over time. Right.
I wasn't that way a decade ago.

Speaker 1 I got into longevity. I'd started human longevity with Craig Venter, Bob Huri, back in 2000 and

Speaker 1 2012.

Speaker 1 That is,

Speaker 2 that makes you a great grandfather of Long John.

Speaker 1 Yeah, I got Brian Johnson.

Speaker 2 I'm just the father of Long Jack.

Speaker 1 I got Brian Johnson into longevity. It's very funny.

Speaker 1 That's awesome. Yeah.

Speaker 2 Well, he definitely caught the bug. He did.
Yeah, we were talking about this before. I think he's showing us what's possible, maybe not what's practical.

Speaker 2 And I say somewhere between the intersection of a Brian Johnson and, you know, and

Speaker 1 what we're talking about here. I think that's really important because

Speaker 1 there are very practical things. It really is an 80-20 rule.

Speaker 1 If you feel like you have to do it all to get that additional health span, right? And let's upfront say it's not really lifespan we're talking about. It really is health span.

Speaker 1 You know, today the average lifespan in the United States is call it 79, but the average health span is 63, meaning you're living till 79. Hopefully, everybody here is going to have a vision of

Speaker 2 my listeners are going to live to 120.

Speaker 1 Yeah, they're fantastic.

Speaker 2 I'm greatly offended by what you just said. I'm sorry.

Speaker 1 I'm just kidding. I apologize.

Speaker 1 But the reality is that

Speaker 1 most people are healthy till 63. Then there's a 16-year gap.
Yes. And our goal here is, can we at least move your health span up to that 80-year mark?

Speaker 1 And yeah, I believe that we're that this is the decade of a health span revolution, of a lifespan revolution as well. And, you know, half my life is in the longevity world.

Speaker 1 Half my life is in the the AI world. And the biggest impact is going to be coming from AI.
I agree with you. Right.
We're a collection of 40 trillion cells.

Speaker 1 Every cell is running one to two billion chemical reactions per second.

Speaker 1 And there's no way for any human to understand

Speaker 1 the vastness of that, but AI can.

Speaker 1 And we're going to be making discovery after discovery after discovery. But it all begins with

Speaker 1 sleep, diet,

Speaker 1 exercise, and mindset. Dial those in first.
Yes. And then get ready for an extraordinary ride in the decade ahead.

Speaker 2 Yeah, I totally agree with you. I think that about every half decade,

Speaker 2 we're going to see three centuries of medical advancement.

Speaker 2 And what I mean by that is when you have artificial intelligence that can take 700 trillion independent variables and create an actionable result, when you stop doing clinical trials where you study things in isolation, you know, you take a cell out of the body, you look how it behaves in a petri dish, and then you assume that when you put it back into its community, that it's going to behave the same way.

Speaker 2 I think, you know, you're talking about leaps and bounds. And, you know, I mean, I think the old

Speaker 2 arcane, in my opinion,

Speaker 2 you know, randomized clinical trial, placebo-controlled

Speaker 2 trial that takes, you know, eight or 10 years and then comes out with a compound that, let's say, gets it gets FDA approved and then goes into the market for 10 years and gets data.

Speaker 1 And by the way, it only works for 20% of the people who it's prescribed for.

Speaker 2 Right. And you don't figure that out for 20 years, you know, until you get really large data and they go, oh, well, we made a mistake and we either pay a fine or take something off the market or

Speaker 2 change it up.

Speaker 1 I mean, those cycles are so long.

Speaker 2 And then, and then I think we also have the inhibition. And I don't mean this in a negative way, but the regulatory environment just doesn't have the capacity to keep up.

Speaker 2 I mean, with the pace of innovation. So I think that stalwarts a lot of what people have available to them.

Speaker 2 So, you know, a lot of treatments that I I believe really can extend life or at least extend health span, stem cells, exosomes,

Speaker 2 natural killer cell treatments,

Speaker 2 blood filtration.

Speaker 1 And we can talk about all of those. Yeah.
And

Speaker 2 I actually want to go down that road.

Speaker 2 First of all, I'm glad that we agree on the foundation because I think that the greatest shift in humanity, like when you, I was a mortality expert for many decades.

Speaker 1 And the best.

Speaker 1 That must have been a great line for opening up your dating conversations. Yo,

Speaker 2 chicks love mortality experts.

Speaker 1 They love them.

Speaker 2 I mean, you can predict death to the month, man.

Speaker 2 It's a great party trick.

Speaker 2 Here, give me your wrist. Let me feel your pulse.
And I'll tell you.

Speaker 2 But,

Speaker 2 you know, I think my wife would probably disagree with that. But,

Speaker 2 you know, but

Speaker 2 what's really interesting is,

Speaker 2 you know, there's so many people that are fascinated by this life extension, you know, extending our

Speaker 2 lifespan. And I believe that there's evidence-based modalities

Speaker 2 and things that we can do, but

Speaker 2 they're just not available in the United States.

Speaker 1 You have to travel outside. And hopefully that will change in the EU administration

Speaker 1 under RFK. Yes.

Speaker 1 And there's so much, it's a disservice that some of my closest friends, some of

Speaker 1 our members at Fountain Life to get advanced therapeutics need to travel outside the U.S. to

Speaker 1 Costa Rica or Mexico, other places.

Speaker 1 And

Speaker 1 that is all going to change. The data is going to materialize as well as regulatory reform to support that.

Speaker 2 And so, having been a mortality expert,

Speaker 2 we studied mortality and lifespan. And the greatest advances in life expectancy weren't like major medical breakthroughs or specific tinctures.
They were

Speaker 2 sewers, sanitation, sanitation,

Speaker 1 vaccines,

Speaker 1 pasteurization of milk. Yeah.

Speaker 2 I mean, these were, these were massive jumps in life expectancy. And I think now

Speaker 2 what's happened, because I think that aging is the aggressive pursuit of comfort and people don't want to challenge themselves anymore, is we've actually gotten away from the basics, the basics that you just talked about.

Speaker 2 And

Speaker 2 I don't think that the majority of Americans even think of muscle as an organ. Right.
I mean, you know, they don't think of it about it being our metabolic currency.

Speaker 1 Yes.

Speaker 2 And so I want to talk a little bit about that, and then I want to get right into some of the things that are really exciting you, like blood filtration, stem cells, exosomes, some of these, some of these amazing things coming.

Speaker 1 I mean, should we hit some of the basics so that coming out of this podcast, people have some actionable items right away? Yeah, yeah.

Speaker 2 I mean, most people aren't going to go, hey, I'm going to Panama and getting a $25,000 stem cell IV.

Speaker 1 But let's break them down.

Speaker 1 First, on diet,

Speaker 1 it is,

Speaker 1 if you think about your body, your genetics, what powers you evolved 200,000 years ago on the savannahs of Africa. And our DNA has not changed very much in 200,000 years.
And back then,

Speaker 1 two things were true. Number one, there was no sugar in the environment.
You had some small amount of natural fruits. There was no refined sugar.

Speaker 1 And the second was there, you know, feeding was intermediate.

Speaker 1 There was no defined gluttony of food consistently. We didn't have Whole Foods or McDonald's.
And so

Speaker 1 today, what I tell people, if you want to go on the diet front, what you can do for yourself, number one, it's cut out this poison called sugar.

Speaker 1 Sugar, refined sugar, is a neuroinflammatory, a cardiac inflammatory. We just did a study at Fountain Life.

Speaker 1 in which we looked at cardiac disease as a function of a bunch of things like LDL, HDL, triglycerides, LP-little A, all these things you hear about.

Speaker 1 And the number one correlant to heart disease was none of those things. It was your hemoglobin A1C.

Speaker 1 It was what was your average blood glucose levels over the last three months. And so sugar correlates with heart disease.

Speaker 1 It also correlates with obviously diabetes and correlates with neurodegenerative disease. So can you minimize that first and foremost? And it takes a while.
Sugar is addictive.

Speaker 1 But I've trained myself to minimize that in my diet. We actually ran

Speaker 1 a no-sugar challenge for 22 days that a friend of mine, Guillermo Nevarate, ran for my abundance community. And if you do it as a group,

Speaker 1 it's a lot easier to do. Yeah.

Speaker 1 Whole plants, of course, everybody talks about whole plants. It is true.
I'm not going to go, you know, plant versus animal protein.

Speaker 1 I mean, minimizing sugar, whole plants, even the order which you eat your food, right?

Speaker 1 So when you're sitting down at your, at your plate at lunch or dinner, eat the vegetables first, which is the fiber going through your small, your stomach and small intestines. It slows it down.

Speaker 1 It allows you to absorb nutrients. Eat your protein next.
And then eat your carbs last if you have room.

Speaker 1 Just doing that alone will flatten your

Speaker 1 insulin curve and help you lose weight. Anyway, I mean, those are just some few.

Speaker 2 I mean, you know, and I think when you look at blue zone dieting or blue zone diets, there was no really specific continuity between diets other than that they were all whole foods.

Speaker 2 I mean, Sardinia was very different from the Mediterranean, very different from Singapore.

Speaker 2 You had very high meat consumptions, long life expectancies, very high carbohydrate consumptions with long life expectancies, and then you had very high fat consumptions with long life expectancies.

Speaker 2 But they were all whole foods. And none none of those people were eating a processed diet.

Speaker 2 Yeah, um, you didn't find the herbicides, pesticides, insecticides, glyphosates, you know, the red dye number 40s, you know, all the things that we invented in the agriculture revolution.

Speaker 1 And we slowed it down a little bit, right? I mean, at the beginning of your meal, take a deep breath.

Speaker 1 I love that, put yourself in a parasympathetic mode, say gratitude,

Speaker 1 chew the food 20 times. You know, we talk about all these GPL, GLP-1

Speaker 1 drugs.

Speaker 1 You can induce that same impact by just chewing your food and nutrients. And slowly.

Speaker 1 Yeah.

Speaker 2 Yeah. I mean, I don't think most people realize that the GLP1s, the semaglotides and trsepatides,

Speaker 2 these are just mimicking hormones that we produce in our gut. And

Speaker 2 they respond to, they create satiety based on nutrient density. And,

Speaker 2 you know, so when you're eating highly processed foods, they're not nutrient dense. You're hungry more frequently and you have a tendency to overeat.

Speaker 1 It's crazy. I've been saying, you know, our kids' cereals should have black box warnings on them.
Like a cigarette.

Speaker 2 Yeah.

Speaker 1 Yeah. I agree with that.

Speaker 2 I totally agree with that. There's a big movement to get Kellogg's to take, you know, the food dyes, you know, out of the, out of the cereals.
I'm, I'm like, why don't we just get rid of the cereal?

Speaker 2 I mean, you know, we, you know, taking the food dye from red dye number 40 to a beet juice dye is great.

Speaker 1 I mean, honestly, we're marketing this to our kids. Yeah.

Speaker 2 Yeah, it should be, it should, I think this has, I mean, this is a whole different conversation, but this has to go with, you know, the corruption in our, you know, the, our research institutions and the stranglehold that big food and pharma has on our public policy.

Speaker 2 And that research needs to be independent. I mean, NIH needs to be, in my opinion, it needs to be a publicly funded, taxpayer-funded, independent

Speaker 1 under RFK that this will make some significant changes, whatever your politics, make America healthy again, fundamental stuff.

Speaker 2 Yeah, I mean, it's hard to disagree with,

Speaker 2 you know, the statistics. You know, we've got the highest rates of childhood cancer in recorded history.

Speaker 2 We just now, as of December 6th, I just saw this article in the Daily Mail.

Speaker 2 As of December 6th, we're ranked 66th in the world in life expectancy. Four and a half trillion dollars a year on we spend on health care.

Speaker 1 And we're ranked, I mean, our ROI on healthcare is horrible. It's negative.

Speaker 1 So, in the category of diet, it's not that difficult, right?

Speaker 1 It is drink enough water i don't do sodas um caffeine i'll you know it depends on what your genetics are if you're a slow or fast metabolizer right that's easy i minimized um alcohol like to half a glass of wine socially a week but you know it's a good lubricant for social but don't abuse it it is it is another form of sugar but minimizing sugar eating whole plants if you do just those two things and slow it down when you're eating your food really hard and don't watch don't watch the Crisis News Network while you're eating your food.

Speaker 1 Don't watch it.

Speaker 2 Don't be in a sympathetic state

Speaker 2 while you're trying to eat your food.

Speaker 2 All right, let's get into the good stuff.

Speaker 2 Because I think we...

Speaker 1 Can I hit one more thing, which is mindset?

Speaker 1 I think people don't recognize how powerful mindset is on your health. And there's a study I just want to quote

Speaker 1 in here that I write about in the book.

Speaker 2 By the way, I'm going to put a link to the Longevity Guidebook in the show notes below. I mean, this is available now, but before you sent me a pre.

Speaker 1 Yes, it is available. I am donating 100% of all profits to the XPRIZE Foundation.
We've got

Speaker 1 a large health span prize I'll mention.

Speaker 1 I also,

Speaker 1 you can order on Amazon. Great, 26, 27 bucks.

Speaker 1 I have it available. If you go to longevityguidebook.com, it's like $12 cheaper.

Speaker 1 And it's basically, I do it at break even.

Speaker 1 I want to get this out there. For me, making, you know, a few bucks on a book is not the goal.
It's how do I get this out there? People should be empowered.

Speaker 1 This is the most extraordinary time ever in human history. I agree.
I want to watch and see and participate in as much of it as possible.

Speaker 1 Me too. And I want people to have that vitality, that love, that life, that health.

Speaker 1 All right. So here's two data points here

Speaker 1 on mindset. Cause I I think mindset is one of the most important things that people don't connect to your longevity.
So this is in a study of 69,744 women and 1,429 men.

Speaker 1 So it's a large-powered study, many more women than men, published in the prestigious journal Proceedings of the National Academy of Sciences. You don't get higher level than that.

Speaker 1 It was found that optimistic people live as much as 15% longer than pessimists.

Speaker 1 It's like a double dividend. Wow.
And if you're not optimistic, get around people who are optimistic. Yes.
Here's

Speaker 1 another fun,

Speaker 1 and this is the power of mind over

Speaker 1 death. So it's one of my favorite stories coming from the annals of American history.

Speaker 1 So as it turns out, in an extraordinary demonstration of the will to live, Two of America's founding fathers, Thomas Jefferson and John Adams, both willed themselves to live long enough to see the 50th anniversary of the Declaration of Independence.

Speaker 1 Even though the average life expectancy was only 44 years old in the early 1800s, Jefferson, who was 83 and Adams, who was 90, made it to July 4th, 1826, both dying on that exact date, the 50th anniversary of the nation they had founded.

Speaker 1 Wow.

Speaker 1 Isn't that powerful? Wow. I mean, if you, another friend, you know, Dan Sullivan says, make sure that your future is bigger than your past.
Yeah. Having a purpose to live for, yes, is so important.

Speaker 2 That was, that, that actually came out in the Blue Zone research too, the sense of purpose, sense of community. Yes.

Speaker 2 Mobility into later in life. You know, we know from the mortality research that the group I did was a part of that sedentary lifestyle is now the leading cause of all cause mortality.

Speaker 1 Siving is the new smoking.

Speaker 2 Yeah, it really is. It's the new smoking.
Hey guys, I'm really excited to announce this. Perfect Aminos has gotten a serious upgrade.

Speaker 2 They've added nucleotides, the building blocks of our nucleic acids, DNA and RNA. And this is important.
We know essential amino acids are the building blocks of protein and collagen.

Speaker 2 Having all the essential amino acids in the correct ratio is necessary for complete protein synthesis without the caloric impact.

Speaker 2 But if we want perfect protein synthesis, we need to look at the process of protein synthesis itself.

Speaker 2 Because if the process is faulty, we won't get the correctly made protein, collagen, fibrin, or the red blood cells in our bloodstream or our muscles.

Speaker 2 We can even stop creation of specific proteins, which can affect us in so many different ways. Our DNA and our RNA are what direct protein synthesis, building new proteins.

Speaker 2 If our DNA or RNA get damaged from toxins, harmful bacteria, or just plain aging, we get faulty protein synthesis. So cells, enzymes, and hormones are less functional and we get premature aging.

Speaker 2 By adding nucleosides and nucleotides, the building blocks of the nucleic acids, DNA, and RNA, our cells get exactly what they need to help repair faulty DNA and RNA and improve the process of protein synthesis itself.

Speaker 2 This is next-level science, and you need to try these. Now, let's get back to the Ultimate Human podcast.

Speaker 2 We both have that childlike curiosity and fascination with the extension of life.

Speaker 2 And I think the majority of the really promising research has gone into the serum of the blood, through the wall of the cell, through the cytoplasm, and into the mitochondria.

Speaker 2 And I think we know mitochondria are not just the powerhouse of the cell, but they are the key,

Speaker 2 in my opinion, in the opinion of many, to longevity.

Speaker 2 So what are some of the things that are really exciting you?

Speaker 2 I asked you this question the other day when we were on a Zoom call, and I really enjoyed your answer, but what's some of the things that are really waking you up in the morning and exciting you about the field of longevity?

Speaker 2 Yeah.

Speaker 1 So, when I wake up in the morning, the very first thing I do is give gratitude. All right.
It's like my instant reaction. Thank you for the ability to live another amazing day.

Speaker 1 And can I contribute the maximum I can? And I just, it's like being excited to see what's going to, you know, there's infinite possibilities we're living in and just excitement for the day.

Speaker 1 And a lot of the breakthroughs coming are

Speaker 1 across everything. So I have a $600 million venture fund in biotech called Bold Capital and Bold Longevity Growth.

Speaker 2 B-O-L D? Bold Capital. B-O-L D.

Speaker 1 Yeah, Bold. And we're in our fourth fund now.
And so I see a lot of deals.

Speaker 1 And then I run something called the Longevity Platinum Trip.

Speaker 1 Dr. Yanni Basaltis and I scan through 500 companies and we pick 50.
And every year, it's a new crop of 50. And we spend five days.
I bring my abundance 360 members in who want to be part of it.

Speaker 1 And we meet with the CEOs of all these companies.

Speaker 1 And a lot of the people there to invest or just learn.

Speaker 1 And

Speaker 1 this year

Speaker 1 or last year, 2024, was the first year we're starting to see, instead of theory, actual therapeutics, actual things becoming available.

Speaker 1 I mean, I can jump into some of them. Yeah, yeah, no, I want to hear about some of them.

Speaker 2 And my audience, this is right up there.

Speaker 1 Yeah. So

Speaker 1 one of them that I love is a company called Immunus.

Speaker 1 Dr. Hans Kirsted, this is his fifth company.
He's had four increasingly bigger exits. He's brilliant in stem cells.

Speaker 1 And what he identified was a, he created a IPSC derived and an embryonic cell derived stem cell that he can grow and it puts out 450

Speaker 1 discrete molecules and exosomes consistently. It's a muse cell?

Speaker 1 It's not a musell, but it is a, and I'll let him define it when he's ready to release it.

Speaker 1 They just completed, so what they've done is that there's 440, actually 440 secretome that comes out of these cells.

Speaker 1 He's been able to characterize it, consistently produce it, and turn it into a drug. And the FDA has allowed him to use that as a drug.

Speaker 1 So they just completed their phase one two-way study in which they were injecting IM

Speaker 1 twice a week for three months.

Speaker 1 And he's figuring out whether once a week or whatever the protocol will be. But his first 18 patients were 50 to 75 years old.
They were severe osteoarthritis, meaning they couldn't walk.

Speaker 1 They were in pain.

Speaker 1 And he did this for a three-month period. And here's the results.

Speaker 1 Number one, these people who were effectively in bed rest, right? Yeah. Because

Speaker 1 of the pain, because they couldn't walk, their skeletal muscle mass increased 6%.

Speaker 1 Without

Speaker 1 exercise. Zero exercise.
Wow. Yeah.
Amazing.

Speaker 1 Number two, their pain reduced as much as 70%.

Speaker 1 They were able to reverse their immune age by 30 years. Wow.
And reduce their inflammatory markers by 50%.

Speaker 2 And there were no other interventions. Zero.

Speaker 1 Fasting. And it's consistent across everybody, no adverse reactions.
And so he's doing an expanded trial.

Speaker 1 I have signed up to be, you know, of course you have.

Speaker 2 I mean, we're going to talk about me signing up as soon as this podcast is over.

Speaker 1 So we're actually, we've cut a deal with between him and Fountain Life. So Fountain Life is my diagnostic and therapeutic centers.
Tony Robbins and I and Bill Capp started this a couple of years ago.

Speaker 1 We have four centers today in New York,

Speaker 1 in Naples, where you started in Orlando,

Speaker 1 in Houston. We're adding next year LA,

Speaker 1 Phoenix, Dallas, and probably Miami.

Speaker 1 And then we've got a growth path for another 25. Anyway, we're making this therapeutic available at no cost to our Fountain Life members as part of the expanded trial he's doing.

Speaker 1 So very, very excited about that. Wow.
Because our members are fully characterized. Yeah.
And we know they're healthy. We know what shape they're in.

Speaker 2 Yeah. All their data.
You know,

Speaker 2 for folks that are not seemingly familiar with stem cells, and I don't want to put words in Peter's mouth, but these cells that you harvest either from Morton's jelly or, you know, these placental cells or placentas,

Speaker 2 very often you can put these cells in specific type of media and they react to different ways.

Speaker 2 You know, these sacratomes you're talking about or exosomes are a reaction to the cell's media, what its environment is.

Speaker 1 And it's pumping these factors out based upon the environment it finds itself in.

Speaker 2 Yeah, and you can get high molecular weight, high aaluronic acid. You can get growth factors.

Speaker 2 So

Speaker 2 you can manipulate the cell. to secrete these exosomes or secretomes that are specific to the outcome that you want.

Speaker 2 Maybe it's joint repair or it's collagen elastin and fibrin or if it's inflammation reduction.

Speaker 2 And again, I don't purport to be a stem cell scientist, but I'm fascinated by how they can take this one pluripotent cell and they can bathe it in different media.

Speaker 2 And it literally is like a chemical factory. And depending on its environment, like a human being, it can have hundreds, if not thousands of different reactions.

Speaker 2 And then you can capture the byproduct of that stem cell's reaction and use it to treat. specific conditions.

Speaker 1 There's a lot coming

Speaker 1 in that realm. I'm the co-founder and vice chairman of a company called Cellularity, which I love.
Bob Hururi, who is an MD PhD, Tony Robbins and I, and Bob Hurri wrote a book called Life Force.

Speaker 1 Yeah, Tony's everything.

Speaker 1 Tony's a dear, dear friend. And we start a few companies.
He's amazing.

Speaker 1 I have nothing but love for him. But

Speaker 1 Bob Hurri would be a great guest. So Bob figured out early on that the placenta is really the 3D printer that manufactures the baby.

Speaker 1 And at the end of childbirth, most people, you know, you don't know this, but you're paying the the hospital to incinerate and get rid of the placenta,

Speaker 1 which is like, if your baby was born with an extra set of lungs, kidney, heart, liver, would you like throw them away?

Speaker 1 And so one of the things that cellularity has is a division called

Speaker 1 First Bank USA, in which

Speaker 1 you can

Speaker 1 save your child's placenta, you decelerize it, you pull out the stem cells, the natural killer cells, the T cells, the exosomes, and so forth, and it's cryopreserved.

Speaker 1 So that your child for the rest of its life has a day zero set of its own stem cells forever. So both of my boys, who are now 13,

Speaker 1 when I go visit cellularity's headquarters, I go say hello to the nitrogen doer that has their stem cells in it. That's awesome.

Speaker 1 But, you know, we talk about Wharton's jelly, we talk about umbilical cord. The placental stem cells are probably the most powerful.
Really? And so cellularity is developing those products as well.

Speaker 1 And hopefully, they'll become allowable. We'll put those through fountain as well when they become approved in the U.S.

Speaker 2 When you say allowable, we can use them topically and intra-articularly, right?

Speaker 1 I mean,

Speaker 1 so no, so today,

Speaker 1 the FDA does not allow any stem cells, really.

Speaker 1 If they're your stem cells, like from fat, post-oriented, or you know,

Speaker 1 and they're not manipulated, meaning they're not expanded. You're taking them out of your fat, which has a high population.

Speaker 1 And your fat is actually one of your younger, is one of your, how do I put it this way? The stem cells in your fat are the youngest stem cells in your, in your body.

Speaker 1 Your stem cells from your blood marrow are just recently manufactured, but fat stem cells can be as much as eight years younger. You can pull it out.
and you can purify them and put them back in.

Speaker 1 But that's fine. But the more interesting thing is, can you manipulate them and make them expand them?

Speaker 1 There's another thing you can do. You can actually co-incubate your stem cells with young stem cells, like from a newborn,

Speaker 1 across a filter. But the exudate, the secretome of the young stem cells will rejuvenate your stem cells.
Wow. So there's a lot of work that Bob and others have done in that realm.

Speaker 2 I've seen some studies on this in plasma exchange. Even Brian Johnson even did it.

Speaker 1 Well, I've done five therapeutic plasma exchanges. But not just replacing.

Speaker 1 Yeah.

Speaker 2 Yeah. I've done that.

Speaker 2 Dr. Deshaun did it for me over at Next Health.
I did the therapeutic plasma exchange, which was amazing because which is essentially where they take your plasma out.

Speaker 1 I took about two liters out. It was quite a bit.

Speaker 2 Typically.

Speaker 2 And then replaced that with sterile albumin. I was very tired that night, but it actually worked out because I did it in L.A.
And then I had a 15-hour flight, non-stop flight to Dubai.

Speaker 2 And I was on Emirates, so I just laid the sea flat and crashed.

Speaker 2 But the next day,

Speaker 2 I woke up with like a level of clarity I don't recall having in probably 10 years. You know, I, I, um, I, I just felt cognizant, clear, awake, focused, just switched on.

Speaker 1 And therapeutoplasmic exchange or TPE, uh, we have those

Speaker 1 that are available at our Fountain Life centers as well.

Speaker 1 Okay, amazing. So, um,

Speaker 1 all of your centers do that?

Speaker 1 Our headquarters right now in Orlando, we will be rolling it out to all the centers in the year ahead. That's amazing.
Yeah.

Speaker 1 And it really is, you're hooked up to a machine. It takes about two hours.

Speaker 1 You pull out about two to two and a half liters of blood, about half of your blood supply.

Speaker 1 Plasma, yeah.

Speaker 1 Well, of the, of all the blood, it spins out the red cells and white cells and platelets and it puts them over here. It pulls out your plasma, which I think of it as my oil change, right?

Speaker 1 And then it gives you fresh saline and plasma,

Speaker 1 puts the cells back in and returns that to your body. So you're pulling out all the inflammatory factors.
Now, for a number of diseases, like neuro-related diseases, it's life-savings.

Speaker 1 For others,

Speaker 1 and I think Dr. Kiproff, who developed this,

Speaker 1 sees like a reversal of three to five years on your epigenetic age. But it really matters how do you feel at the end of the day?

Speaker 2 No, how do you feel? And I think our plasma is a

Speaker 2 repository for a lot of the junk, mold spores, mycotoxins, metals, viral pathogens, cytokines. There are all kinds of things that are floating around in the plasma

Speaker 2 that are not being evacuated.

Speaker 1 Another company that you and I are both fans of, Extera Medical,

Speaker 1 is really fabulous, right? So here's a technology coming out of DARPA years ago and developed jointly in Sweden in this blood filtration system that has got

Speaker 1 40 square meters, about the size of a tennis court worth of this material called a glycocalyx that filters out all viruses, all bacteria, all circulating cancer cells.

Speaker 1 I mean, amazing.

Speaker 1 And there's a very real phenomenon people don't talk about called immunoexhaustion,

Speaker 1 if you've heard of that term. So

Speaker 2 I understand what it is. Yeah,

Speaker 1 as we grow older, we have been burdened with all of these different viral infections.

Speaker 1 Besides COVID, maybe you have Epstein-Barr virus, maybe you have cytomegalovirus, maybe you have a multitude of other viruses that you're, they're not active, they're in your body. Yeah.

Speaker 1 And on occasion when you get run down or stressed, they start coming out. And your immune system needs to fight.

Speaker 1 all these viruses and cancer. And it's the same innate immune system, your natural killer cells.

Speaker 1 And so it can become overloaded. It can become exhausted.
Yes. And so one of the things I like about Extera Medical, and we're rolling that out through Fountain as well.
I'm solving.

Speaker 1 Yeah, we're Fountain, you get a 15K discount on the blood filter systems if you're a Fountain member, which I'm proud of.

Speaker 1 It's the ability to... filter out all of these pathogens and give your immune system a deep breath.
Yeah. A chance to, okay, now we're going after you.
Yeah. Yeah.

Speaker 2 You're just taking, you're taking it from having to fight on so many different fronts, having to fight on fewer fronts. And I think you, you glossed over something, but I want to I want to drill in.

Speaker 2 So this, this, this filter, it's think of a dialysis machine. Yes.
And that's probably the closest thing for people to

Speaker 2 analyze what it is.

Speaker 2 And you pull the blood out and it runs through this filtration system and they have heparin binding sites, which very, when he says the endocalyx, the glycocalyx, what he means is it's mimicking sort of the lining of the artery, the wall of your side of your blood vessels, which is where these pathogens like to go.

Speaker 2 And so they see this surface as the surface area of your blood vessels, and they attach to it, and they can be taken out of the body.

Speaker 2 And what I found fascinating, and I'm going to have their lead oncologist on the podcast. Is it Dr.

Speaker 1 Mink Chella? Yeah, Dr. Chala.
He's brilliant. Oh, he's so brilliant.

Speaker 2 And he's so well spoken. And I've done a number of Zoom calls with him.
And I like.

Speaker 1 He's a very giving human being.

Speaker 2 Very brilliant, but also very well-spoken so that, you know, he's not just talking from PhD to PhD. He really has a way of fundamentally helping you understand.

Speaker 2 And obviously he's an oncologist.

Speaker 1 So that helps. But

Speaker 2 how he was explaining this to me, which made perfect sense, was, you know, along the lines of this immunoexhaustion where,

Speaker 1 you know, all of us us at some point in our life have had circulating cancer cells now immune system is taking care of them yeah people need to understand your body is always producing cancers it is you know there's something called the hayflick limit that a cell divides 50 times and then should have the decency to die But sometimes it becomes an inflammatory cell, a grouchy old man cell,

Speaker 1 a senile cell.

Speaker 2 Senescent. Yeah.

Speaker 1 Other times it becomes a cancer. And when that happens, your innate immune system, your NK natural killer cells, typically detect it and kill it.

Speaker 1 But sometimes it evades those and they become a cancer.

Speaker 2 And, you know, and

Speaker 2 all cancerous cells were at one time a healthy cell. I mean, they became metabolically sick.

Speaker 2 And the idea is if you can get these metabolically sick cells out of the bloodstream or the circulating. tumor cells,

Speaker 2 now the

Speaker 2 immune system has less to do and it has more time time and more strength to focus on whether it's a nodular cancer or something else

Speaker 2 that's going on in the body. And I really found that fascinating and also found it fascinating from the risk standpoint because things like chemotherapeutics and high dose radiation or

Speaker 2 aggressive surgical resection. I mean, those have real.
consequences. They may be necessary, but they have very severe consequences and may not work.

Speaker 2 Whereas, you know, a blood filtration,

Speaker 2 if your downside is that it doesn't work, I mean, your upside is at least that it's not very likely.

Speaker 1 And by the way, it's probably going to help you, if not on the directly in the cancer, it will help you on getting rid of your viral loads.

Speaker 1 It's about really giving your immune system a chance to take a breath and defend you.

Speaker 1 You know, one of the things I'm very proud of, I'd like to mention is our Health Span prize. So

Speaker 2 this is fascinating.

Speaker 1 Yeah. So folks who don't know me from the X Prize perspective, 30 years ago, hard to believe, I launched our first $10 million prize.

Speaker 1 So I offered up $10 million for the first person who could build a private spaceship, go to 100 kilometers, land, and make the trip again with the same ship within two weeks.

Speaker 1 This was way before SpaceX and Blue Origin and space was not a common conversation. And the idea of commercial space didn't exist.

Speaker 1 An amazing woman, Anusha Ansari, who's now the CEO, I serve as chairman of the XPRIZE, put up the 10 million for a family.

Speaker 1 I put up the first, you know, I don't know, I hadn't had that much money back then, the first hundred thousand or so. And it worked.

Speaker 1 And on the heels of the XPRIZE getting one, the first one in 2004, I was able to attract Elon Musk on my board, Larry Page, James Cameron. It's like, you know, everybody loves a winner.

Speaker 1 And so we turned the foundation into an organization. that was launching large-scale global competitions.

Speaker 1 And we're saying, I don't care where you went to school, what you've ever ever done, if you demonstrate and solve this problem, you win the money. So we've launched 30 prizes, about $550 million

Speaker 1 of competitions driving close to $8 billion in RD. And this is not like a Nobel prize that you award somebody for something done 30 years ago or 10 years ago.

Speaker 1 This is a prize where we say, okay, the first person to do this, it was modeled after

Speaker 1 the prize that Lindbergh won flying from New York to Paris. It was a $25,000 prize offered for the first person to fly.
Nine teams made the effort. Lindbergh won.
Wow.

Speaker 1 I did not know that. And so we've launched 30 prizes mapping the ocean floor, pulling water out of the atmosphere.

Speaker 1 They see five years ago, I got Elon to fund a $100 million carbon extraction prize, which will be awarded this coming April for pulling CO2.

Speaker 1 out of the atmosphere and out of the oceans at mass it's an amazing prize wow i call i I'd love to know how that technology works.

Speaker 2 Yeah.

Speaker 1 Well, you'll find out. Okay.

Speaker 1 In like

Speaker 1 January of 2020, Elon became the most wealthiest person on the planet. And he was getting a lot of crap for not being philanthropic.
So I texted him. I said, why don't you fund an X prize?

Speaker 1 He says, What do you have in mind? I said, How about one around carbon? He said, How much? At 100 million. He said, He wrote back, sure.

Speaker 1 I love Elon.

Speaker 1 And then a month later, we were assigned and he put up the money.

Speaker 1 That's great. So for the last five years, I was like, there's got to be a prize

Speaker 1 in the longevity space. And

Speaker 1 we ended up designing a prize, you know, folks like George Church and David Sinclair, Ray Kurzweil.

Speaker 1 I'm blanking on his name, Aubrey DeGrey, who really was the first person to prompt me on this. And we designed this prize and I raised $141 million.

Speaker 1 And this is a prize that was launched a year ago. And to win this, you need to demonstrate a therapeutic that you could deliver in one year.

Speaker 1 So imagine someone comes to you, I'm going to give you, for Gary, for a year, we're going to give you this therapy.

Speaker 1 And the impact is going to be that your cognitive immune and muscle will be 20 years younger. Wow.
Right. So we're not looking at

Speaker 1 your epigenetic age or anything like that. What we're looking at is how do you feel?

Speaker 1 Do you have the ability to build muscle, maintain muscle as strong and capable as you did 20 years earlier? Do you have the cognitive span of memory?

Speaker 1 Do you have the immune function to mount a reaction to a, you know, how are you measuring that?

Speaker 2 Just

Speaker 1 a hand marker. There's a whole, no, we're doing it.
We'll do an immune challenge. We'll give you a, you know, a vaccine and how well do you mount a response to that

Speaker 1 um and it's functional it's using functional endpoints instead of just um you know markers and so i'm really excited about it because i think that's what really matters yeah i think so too do you feel younger are you are you functioning in a younger state versus oh look at my printout no who gives a about your printout yeah if you don't feel that right so we have and here's the here's the punchline a year later we have 460 teams competing for that

Speaker 1 health span prize 460 teams and they're all trying to reduce the age and how how are you measuring that telomeres like an age again it's it's reversing the functional losses of in immune cognition and muscle so that you know you've got the capabilities you had 20 years ago

Speaker 1 um and amazing companies and so i'm seeing all of these companies and my job is fascinating yeah i've taken myself off the judging judging board and off of all of that so that I can help promote and support them and not be

Speaker 1 in a problem of promoting one over the other. But like yesterday,

Speaker 1 it was a few days ago, this one company that will go from a skin cell,

Speaker 1 regrow a pluripotent stem cell for you, and then

Speaker 1 let's get put aside the ethics here, but create a clone of you, right? On a cellular level.

Speaker 1 So here's a and grow that, that embryonic clone to 28 weeks of Gary, and maybe we'll produce a thousand of those clones. And

Speaker 1 way before the brain is developed and such, in fact, they have a genetic

Speaker 1 change they can make so that the head of the clone doesn't develop.

Speaker 1 But what we can do now is pull out of your clone day zero hemophoetic stem cells that are an exact copy of yours. An exact copy of yours yours of what they were when

Speaker 1 you were young.

Speaker 2 Wow.

Speaker 1 It's amazing stuff coming. Wow.
So I talk about this idea of a longevity mindset. Yeah.

Speaker 1 And I have a whole, you know, again, a chapter in the book about this, that your mindset is the most important thing. And

Speaker 1 if you

Speaker 1 do the work, understand what's going on, right?

Speaker 1 And you realize, oh my God, there is a health span revolution coming and it's this decade.

Speaker 1 And I want to see, I want to be there. I want to be ready for it.
I want to keep myself in the best health I can, right? I don't want to miss it.

Speaker 1 And that's, there's got to be some reason why you don't dig into the chocolate cake. Yeah.
Why you don't like just sleep through your alarm and forget the gym.

Speaker 1 Why you don't get your eight hours of sleep. And that reason for me

Speaker 1 is I want to keep myself.

Speaker 1 First of all, I love being in great shape in terms of feeling strong thinking clearly ability to act having the energy to run circles around my 20 something year old staff members

Speaker 1 but uh ultimately it's about being in the best health i can in order to intercept these breakthroughs

Speaker 2 and when when you say intercept these breakthroughs a lot of these you're um tangenti involved in through

Speaker 1 Through the XPRIZE, through my venture fund, through the companies I advise and so forth. Yeah.

Speaker 2 So who's who's looking at the XPRIZE winner this year? What do you see? What kind of things are you seeing?

Speaker 1 So

Speaker 1 we have, again, these 460 teams. I can't believe there's 460.
Yeah, from around the world.

Speaker 1 From around the world.

Speaker 2 Well, it's 100 million bucks.

Speaker 1 It's 100 million bucks.

Speaker 1 And

Speaker 1 we're going to be announcing. So

Speaker 1 we're staging the money. So we'll be announcing the first.

Speaker 1 40 companies that will get a quarter million each. We'll be announcing those.
It'll be worth keeping your eye out for who those 40 are. Yeah.

Speaker 1 Then about a year, 18 months later, we'll be announcing 10 that will get a million dollars each. All the teams are still in the running.

Speaker 1 And then the remaining 80 million, 81 million,

Speaker 1 is up for grabs for whomever can reverse it. You have to reverse a minimum of 10 years.
The goal is 20. Do I know why it's $101 million, not $100 million? Yeah, yeah, I'm curious about that.
So

Speaker 1 the first donor,

Speaker 1 an amazing man, a guy named Chip Wilson. I don't know if you know Chip.
He's the founder of Lululemon. Okay.
And he has a muscular dystrophy called FSHD.

Speaker 2 I've heard about this.

Speaker 1 And we're on the phone, and he's become a dear friend. I love him.
He's a beautiful human being. And he's like, okay, I don't want to put all the money in, but I'll put a chunk in.

Speaker 1 But he says, how much is Elon's prize again for carbon? I said, it's 100 million. And he goes, can we make ours 101 million?

Speaker 1 And I said, okay.

Speaker 2 Because I want to attract people to Austin, not the Garmin. Yeah.

Speaker 1 Because I said, okay, if you put the extra million in, so he increased his donation to 36 million. And we also have an additional $10 million bonus prize

Speaker 1 for a breakthrough in FSHD. And I'm very blessed.
There's an incredible woman, Jamie Justice, who's a PhD

Speaker 1 who runs this competition.

Speaker 1 I just raised the money and handed her a set of rules. And she's running this thing.
And

Speaker 1 it's doing amazing. So proud.

Speaker 2 Yeah.

Speaker 2 And

Speaker 1 so

Speaker 1 does your book go into some of these topics?

Speaker 2 Or?

Speaker 1 Yeah. So I made this book.
So Tony Robbins and I wrote this book called Life Horses, 700 Pages.

Speaker 1 New York Times bestseller.

Speaker 2 I made my way through an incredible book.

Speaker 2 I've actually put it on my top 10 must reads.

Speaker 1 So it, you know, it was New York Times bestseller for two months, but it's 700 pages. It's hard for someone to read 700 pages.
So I wrote this book as a very digestible how-to.

Speaker 1 Um,

Speaker 1 and you can pick up any piece of it.

Speaker 1 So, yes, there it's like all the details, everything I do and what I've researched, and what works in sleep and exercise and mindset and not dying from something stupid, which is what I love that the, I mean, let me take a second and talk about that.

Speaker 1 But, but then it does go into the X Prize and where these sciences are going.

Speaker 1 There's a chapter called, you know, Don't Die from Something Stupid. What does that mean?

Speaker 1 So you know this. Our body is really great at hiding disease.

Speaker 1 You know, I tell you

Speaker 1 in a room of a thousand or 10,000 people, I'll say, how many of you here are absolutely sure there's nothing going on inside your body you need to know about? You know, raise your hand. And

Speaker 1 no one does unless they've just gone through a, you know, a set of like a fountain life. Yeah, a fountain life diagnostic.
So

Speaker 1 four years ago, Tony,

Speaker 1 Bob Haruri, and I, backing from

Speaker 1 Mark Benioff and others, we built this company called Fountain Life. These are 10,000 square foot facilities.

Speaker 1 We have four today, four more next year, a road, a mode map to get to probably about 30, 35 around the world.

Speaker 1 And you come in, you spend about five hours with us, and we digitize you.

Speaker 1 It's everything knowable about you: full body MRI, brain, brain vasculature, coronary CT with an AI overlay, low-dose lung CT, DEXA scan, retinal scan, skin scan,

Speaker 1 full genome, microbiome, metabolome, full blood workup. Again, everything knowable about you.

Speaker 1 And all of that data then gets digested by our AI system. It's all functional medicine-based.
The entire company is functional medicine.

Speaker 1 We have an amazing chief medical officer,

Speaker 1 Dr. Helen Messier, who teaches functional medicine.
And we have a Fountain University. Our doctors, our nurses, our health coaches, everybody's functional medicine.
And the AI digests it.

Speaker 1 And there are two things we're trying to, you come in to answer two questions. Is there anything going on inside your body right now you need to know about?

Speaker 2 Yeah.

Speaker 1 And what's likely to happen to you, and how do we prevent it from happening? Wow. Right.
I mean, that's

Speaker 1 what you should know. So.

Speaker 1 Here's the results. In our first 5,000 members, 2%,

Speaker 1 everybody coming in is seemingly healthy. 2% have a cancer they don't know about.
Wow. Right.
I mean, think about it.

Speaker 1 You know, someone who went to the hospital, went to the doctor's office with a pain in their side, and it's like, sorry to tell you this, but you've got stage three or stage four. Right.

Speaker 1 And it didn't happen that morning,

Speaker 1 right? It's been going on for some time. And people go, I don't want to know.
I was like, bullshit, of course you want to know. Yeah.
You're going to find out eventually.

Speaker 1 You want to know now when you do something about it or when it's too late?

Speaker 2 Yeah, you are going to find out eventually.

Speaker 1 So

Speaker 1 your body is great at hiding hiding that.

Speaker 1 70% of all cardiac disease has no preceding, no shortness of breath, no pain.

Speaker 1 Even your calcium score doesn't matter, right?

Speaker 1 Your calcium score, calcified plaque, unless it's blocking the coronary artery that feeds the heart muscle, sugar, and oxygen, unless it's blocking it, in which case, yeah, you want to see that.

Speaker 1 Calcified plaque on the side of a coronary artery is stable. What we've discovered in the last few years, it's something called the soft plaque.
Yeah. That's on

Speaker 1 more and more of the arteries, right? So there's a special AI overlay called Clearly, James Minn, Dr. James Minn who invented it is brilliant.

Speaker 1 And it's the soft plaque that in the middle of the night can break off and block your coronary artery and you don't wake up.

Speaker 1 And so

Speaker 1 we

Speaker 1 can detect through this AI overlay your soft plaque.

Speaker 1 Most of the cancers that kill people

Speaker 1 are not cancers we screen for because we screen for breast and prostate and intestinal cancers, but we don't screen for glioblastomas, pancreatic cancers.

Speaker 1 And so

Speaker 1 we find these things. We've saved hundreds of people's lives.
I get thank you notes all the time. Like, God bless you.
Thank you for saving my life over and over again.

Speaker 1 And one of the things that's important is it's not any one thing, it's multimodal, right? Yeah. It's the imaging plus the blood chemistries plus the grail test plus everything.

Speaker 1 All this stuff comes together. So that's what the chapter on that is.
It's not cheap. Yeah.
It's $19,500, but it comes with a medical team for the entire year

Speaker 1 with a physician, a nurse, a health coach, a dietitian. We have just rolled out a $6,500 product.
Wow. called CORE, which is through companies for their employees.

Speaker 2 And that's a scaled-down version of what you're doing.

Speaker 1 It's all of the same testing.

Speaker 1 It's just not with the year-round medical team. The humans still cost a bunch.

Speaker 1 They'll be demonetized and democratized by AI in the years ahead.

Speaker 2 And you plan to bring in AI to overlay a lot of this and make the diagnostic side easier so then maybe it's on my phone.

Speaker 1 I have all of my data. You do.
And on my phone is an AI we call Zora that I can query, like, tell me what you saw in my images.

Speaker 1 Tell me what correlation you have in my blood chemistries and my genetics. You can ask it anyway.

Speaker 2 And that's already functional. It's all, it's here.
It exists. So a fountain life client could put that on their phone, get their diagnostics done, and then start asking questions.

Speaker 1 Yes, your doctor will clue you in.

Speaker 1 And the most important thing is not to get overwhelmed, to give you an actual plan and to have a nurse, a physician, a health coach, a dietitian with you through the year to then, and to get you through and improve.

Speaker 1 And by the way, this is never one and done.

Speaker 1 Right. It is, I do this, I've done this every year originally through human longevity and now for the last four and a half years with Fountain

Speaker 1 because eventually I'll find something. Yeah.
And I'll say thank you.

Speaker 2 Yeah. And you'll find it early enough.
And that's what I talk about a lot: the early detection, the artificial intelligence, and the big data.

Speaker 2 Because one of the things that we realized in the mortality space was the big data was actually more predictive than any kind of randomized clinical trial or a lot of the scientific periodical data that we were getting.

Speaker 2 You know, you could look at large populace of data,

Speaker 2 371 million lives in the mortality database that we used to have access to, and we would see things like what you were talking about earlier.

Speaker 2 Well, there was elevated LDL cholesterol in this entire populace, but the ones that had the lower triglycerides actually had no impact on mortality.

Speaker 2 As triglycerides rose, it actually made the LDL more dangerous. And we had an increase in all-cause mortality.
So just showing that, you know, it's not as linear as we think. Just like

Speaker 2 you were saying,

Speaker 2 the fascination that I have with AI are these 700 trillion independent variables. You talk about the number of methylations.

Speaker 1 And no human can understand all that. No human being.
But AI can take it all in, process it, and help you. And then eventually we'll have our AI coaches which say, hey, Gary, don't take the elevator.

Speaker 1 There's stairs around the corner. Take that.
Like, you know, you'll give permission to your AI to watch everything you do,

Speaker 1 see what you're eating, listen to your, you know, your conversations, your emails, and it will advise you. And so you can turn on health coach.
And the other thing is, you know, I'm wearing a,

Speaker 1 where is it? Constantly,

Speaker 1 my CGM. I'm wearing my aura ring and my Apple Watch, but

Speaker 1 I'm investing in. He's got data.

Speaker 1 I'm investing in all these sensor companies because eventually all of this data is going to be uploaded to my AI

Speaker 1 and uploaded to the robot in my kitchen

Speaker 1 that will cook the perfect food that my body needs that next hour.

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Now, let's get back to the Ultimate Human podcast.

Speaker 2 I mean, that's sort of the Brian Johnson method, right? I mean, he's almost taken himself out of any

Speaker 2 decisions, yeah, the decision processes, and all of his supplements fight for the life, and his caloric intake, you know, is prescribed, you know, right down to the macros and the micros.

Speaker 1 And his erection as well. His erection as well.
He does talk about that a lot.

Speaker 2 But,

Speaker 2 you know, you're also known for taking um up to 75 supplements yeah in in a day um i think i'm up to 80 now are you i'm i'm i'm not far behind you by the way yeah and sometimes i'm afraid to even tell people all the stuff that i'm taking because they'll think wow um

Speaker 1 but how did you formulate you don't have to be hyper specific but how did you formulate this supplement regimen you know i used to have people ask me please tell me and i had this five page document and this 10 page document and i said screw it and so there's a whole chapter in the book of exactly what I take and why.

Speaker 1 And

Speaker 1 I do all of this in consultation with my Fountain Life medical team, right? I'm tested at least quarterly, if not more frequently than that, because I care. Data is power.

Speaker 2 I agree with you. If you don't have data, you don't have nothing to take action on.

Speaker 1 And by the way, I talk about in the book a lot of other lower cost. programs that you can do.
There's Life Force,

Speaker 1 which is around blood testing and supplements. There is Prenovo, which is only the MRI

Speaker 1 without the

Speaker 1 follow-up. So there's a lot of different things, and I list them all so that people have alternatives.

Speaker 1 But the way I think about it, there was a paper published in Cell

Speaker 1 that talked about the hallmarks of aging.

Speaker 1 And they're originally like nine, now they're like 12. And so when people said, why do we age?

Speaker 1 There's a number of very specific elements like stem cell exhaustion.

Speaker 1 I should just say, first of all, our bodies were never designed to live past age 30. I hate to say it, right? If you think about it, 200,000 years ago, you were in puberty at age 12.

Speaker 1 By 13, you were pregnant

Speaker 1 before birth control was around.

Speaker 1 By the time you were 26, 27, 28, you were a grandparent.

Speaker 1 And before McDonald's and Whole Foods was here, If you wanted to perpetuate the species and pass on your genes, you didn't want the grandparent stealing food from the grandchildren's mouths.

Speaker 1 And so

Speaker 1 lifespan was like 30 years.

Speaker 1 And so if we look at this,

Speaker 1 it's just, it is in a lot of things. I talk about this evolutionary rationale and reason from earlier on.

Speaker 1 Our muscle mass starts decreasing after the age of 30. Our hormone levels, right? Our thymus is gone.
Our muscles begin to atrophy. All of these things.
And you can and should fight it.

Speaker 1 And I do with all the efforts and all of exercise

Speaker 1 all those things

Speaker 1 when you look go back to the hallmarks of aging um right our stem cell population so stem cell exhaustion is one of them

Speaker 1 uh the end caps of our dna uh telomeres are telomeres uh there is uh mitochondrial uh you know degradation that occurs There's all of these, and I list all 12 hallmarks of aging.

Speaker 1 And then the way I built my supplements is looking at which are the supplements that can impact each of those 12 hallmarks.

Speaker 1 And there's great science behind each of them.

Speaker 2 So like resveratrol, DHE.

Speaker 1 Well, you know, and

Speaker 1 NAD. So NAD, nicotinamide, adenine dinucleotide, which is the power currency in our cells.

Speaker 1 David Sinclair did a lot of incredible work on this, and kudos to him. You know, we have these seven sirtuins, these proteins, and the sirtuins have two functions in your cells.

Speaker 1 One function is that they are

Speaker 1 correcting DNA mutation that we accumulate as we get older.

Speaker 1 The other function is they keep.

Speaker 2 How do they correct a DNA mutation? So they repair it?

Speaker 1 No, no, no. The sirtuins are

Speaker 1 part of the

Speaker 1 DNA repair system, but they also maintain your epigenetic

Speaker 1 situation. So, what do I mean by that?

Speaker 1 When you're born, when you're 20, when you're 50, when you're 100, you have the same exact genome. Right.
3.2 billion letters from mom and from dad. Your software doesn't change.

Speaker 1 So

Speaker 1 why do you look different

Speaker 1 at 80 or 100? Why don't you have the six-pack you had when you were 18? It's not the software you're running. It's what genes are on and what genes are off.
It's your epigenome. Yeah.
And

Speaker 1 the control of which genes should be on and which genes should be off

Speaker 1 is driven by these seven sirtuins.

Speaker 1 And as we get older, the sirtuins are having to correct DNA damage and keep us from having epigenetic drift.

Speaker 1 And they are powered by something called NAD plus.

Speaker 1 If they don't have enough NAD, and the NAD in your cells drops by over 50%

Speaker 1 as you age.

Speaker 1 And so when David and others talk about NMN or NR as a supplement,

Speaker 1 that is the precursor to NAD.

Speaker 2 So you can't really take the NAD orally. I guess you should do it injectively.

Speaker 1 You can, but

Speaker 1 it doesn't even get into the cell that way.

Speaker 1 It's, you want a precursor like NMN or NR that crosses the cell surface and gets compared to NAD. So the supplements and meds I take

Speaker 1 are to address those hallmarks of aging. And the science is there.

Speaker 1 I present it, but I'm very clear. Listen, this is what I do.
This is why I do it. Do the research yourself.
Find a physician

Speaker 1 and start incrementally. My mom still says to me, Peter,

Speaker 1 how are you sure those things all don't interact with each other in the wrong way?

Speaker 1 I don't know. I don't.
I don't know. Honestly, I don't know.
You feel great, though. Yeah.
Yeah. Yeah.
I mean, that's ultimately, that is ultimately, you know, do you look good?

Speaker 1 Are you thinking clearly? Are you moving well? Are you enjoying life? You know, one of the best pro-longevity things I've ever done is having kids at 50. Wow.
Right. So I had two boys at 50.

Speaker 1 They're, they're 13 now. And a lot, you know, when I go to sleep every night, one of the things I do as a part of my practice is, what are my three favorite memories from the day?

Speaker 1 What am I grateful for?

Speaker 1 And almost always it's around them. Yeah.
It's not some deal I closed or some investment I made.

Speaker 2 Yeah, that's so cool. I feel the exact same way about family.
And this goes back to the whole idea about the importance of community and not being in isolation.

Speaker 2 You know, we knew in the mortality space that if you wanted to cut a human being's life expectancy in half, and I mean at any age, put them in isolation.

Speaker 2 And it would literally cut their life expectancy in half. At whatever age they are, you could have it in isolation.
And I think that,

Speaker 2 you know,

Speaker 2 again, I don't purport to be a mental health health expert by any

Speaker 1 means,

Speaker 2 but I think there's an argument to be made that the amount of social media that we consume, the amount of artificial

Speaker 1 relationships and stimulus that we're scared shitless for my 13-year-olds about AI growth.

Speaker 2 Right. I mean, I don't consider you having access to your phone

Speaker 2 and the media on that phone to be out of isolation. I would actually consider that to be in isolation.
And so,

Speaker 2 you know, with life expectancy, the United States is going backwards.

Speaker 2 It's actually tanking for a whole host of reasons, but not the least of which I believe is we are losing touch with the basics of humanity. You know,

Speaker 2 mother nature, you don't touch the surface of the earth. We don't get much sunlight.
We don't ground. We don't walk in nature.
We, we, we don't have a lot of human in interaction.

Speaker 2 We have a lot more of an electronic, you know, interaction. And I, I believe that this is a form of isolation, you know, it's, it's, it's removing, again, back to the blue zones.

Speaker 2 I mean, there were no such thing as assisted care living facilities. Grandma and grandpa moved back in with the kids until the day they died.

Speaker 1 And maybe her only role was to go get vegetables for dinner, you know? Um,

Speaker 1 but uh, you're so, so right. I mean, human touch.

Speaker 1 You know, I have my favorite hug dealer. hug dealer t-shirt, which I'm not sure if it's socially acceptable now to have that, but it's like, just, just, I mean, it's like,

Speaker 1 it's like, just to give someone a hug and breathe deep with them and just say, thank you for being in my life.

Speaker 1 It's a, it's a, it's a beautiful thing. These are the fundamental elements of life.

Speaker 2 Well, I am really excited that our paths cross. I don't think that you and I have written our last chapter.
I think we're about to talk about

Speaker 1 introduction, my friend.

Speaker 2 Our first chapter together.

Speaker 1 Where do

Speaker 2 people that haven't interacted with you, where can they find you? Where can they find out more about you?

Speaker 1 So, longevityguidebook.com will give you a whole bunch of resources and

Speaker 1 a deep discount on the book.

Speaker 1 Please use this book, even if you just pick one chapter to focus on. My goal is to get this information out there.
You have control over every aspect of your health.

Speaker 1 Take, you know, be the CEO of your own health. It's so truly important.

Speaker 1 You can go to

Speaker 1 fountainlife.com to learn more about those offerings. And I hope people will take advantage of it.

Speaker 1 My podcast is called Moonshots. Moonshots.
Moonshots. Yeah.

Speaker 1 And I've had the pleasure of interviewing Elon a couple of times and Eric Schmidt, a whole bunch of AI experts, a number of folks in the longevity space.

Speaker 1 I'm focused on who's taking the biggest shots in the universe. Who's open for, you know, impacting the world at a tremendous level.

Speaker 1 And I need to have you on my Moonshots podcast. I'm happy to be on there.

Speaker 2 I mean, I'd be honored to be on there.

Speaker 1 Thank you. Thank you.

Speaker 2 I'll take that. You shoot it out in LA?

Speaker 1 I shoot out in LA. Yeah.

Speaker 1 A new studio I built out in Santa Monica. Okay.

Speaker 1 Diamandis.com.

Speaker 1 I put out two blogs a week.

Speaker 1 My job at this point in my life is to inspire. So I talk about something called a massive transformative purpose, an MTP.

Speaker 1 Mark Twain said there are two important days in your life, the day that you were born and the day that you found out why.

Speaker 1 Really beautiful. And so at Singularity and at Abundance 360, which is my CEO level forum,

Speaker 1 I teach creating a massive transformative purpose. And it's something that wakes you up in the morning, keeps you going through the night.
It's what it's what longevity connects with, right?

Speaker 1 Having a purpose and, you know, a future bigger than your past.

Speaker 1 And my massive transformative purpose is to inspire and guide entrepreneurs to create a hopeful, compelling, and and abundant future for humanity.

Speaker 1 So, my job through the XPRIZE, through Singularity, through all of this, is how to help entrepreneurs go big and bold in the world.

Speaker 2 Yeah, that is amazing, man, especially in the area of longevity.

Speaker 1 Especially, yeah, longevity.

Speaker 2 Yeah, that's fantastic. Well, I wind every podcast down by asking

Speaker 2 my guests the same question. There's no right or wrong answer to this question, and that is,

Speaker 2 what does it mean to you to be an ultimate human?

Speaker 1 To be, so to be my ultimate self is to give, put it all out, leave nothing in reserve. And it's

Speaker 1 being true to myself, authentic to myself. It is playing all out on my mission and purpose in life.
It's being a good person. It's knowing that I have left this planet better than I came into it.

Speaker 1 I mean, those are the elements. And

Speaker 1 to make that happen, I need to have the best physical health I have. Yes.
Right.

Speaker 1 Because I'm going 24-7 with my eight hours of sleep in there.

Speaker 1 And I'm just, I feel blessed to be alive. This is the most magical time ever in human history.

Speaker 1 Gosh, I do too. Right.

Speaker 1 One of my favorite slides I use in presentations is a slide that the title is, Our Ancestors Would View Us as Gods.

Speaker 1 Let me just reflect on that for a second.

Speaker 1 The things that we did this morning is, you know, we're omniscient,

Speaker 1 we're omnipotent, we're omnipresent. We are, we are creating new life forms in AI.
I mean, it's amazing the life we're living.

Speaker 2 Yeah, it really is. It is.

Speaker 1 Yeah.

Speaker 2 Well, Peter, I cannot thank you enough for coming on. I mean, this is a true honor to have you on here.
I'm excited to be on your show, too.

Speaker 2 I will put everything that he discussed in the show notes below, guys, including a link to his book. Check Dr.
Diamantis out.

Speaker 2 Absolute mentor of mine. And as always, guys, it's just science.