Episode 304: The Longevity Secret Everyone's Talking About: NAD+ Exposed with Expert Panel!
We discuss the crucial role of NAD for cellular health and energy production, the importance of choosing high-quality, research-backed supplements, and daily habits for enhanced well-being.
What we discuss:
(0:00:01) - The importance of NAD and its rise in popularity among celebrities and biohackers, the significance of NAD in maintaining energy as we age, and its role in various cellular functions
(0:11:56) - The natural methods to boost NAD levels, such as high-intensity training and proper nutrition, and the controversy surrounding NAD precursors NR and NMN
(0:18:13) - The complexities of the supplement industry, the necessity of research and trust in manufacturers is underscored due to the alarming findings of ChromaDex's analysis of NMN products, the signs of NAD deficiency, and the optimal age for supplementation.
(0:29:33) - Daily habits and routines for health and longevity from the experts
(0:35:35) - How to dose NAD
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Find more from Jen:
Website: https://www.jennifercohen.com/
Instagram: @therealjencohen
Books: https://www.jennifercohen.com/books
Speaking: https://www.jennifercohen.com/speaking-engagements
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Transcript
Hi guys, it's Tony Robbins.
You're listening to Habits and Hustle, Greg.
Before we dive into today's episode, I first want to thank our sponsor, Therisage.
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Okay, so we're doing a live podcast, a live panel discussion on the benefits of NAD because there's been such curiosity and there's been lays caught fire on the internet recently with a lot of discussion from like biohackers, celebrities.
Everybody wants to know and curious about all the benefits of NAD, what it does, how it can help you with your lives.
And we're going to be speaking all about it.
We have an expert panel here with some fantastic people.
We have Dr.
Darshan Shah, who is the founder of Next Health and a longevity expert, a surgeon.
He's just a fountain of information, and you'll hear it very soon.
We have Dr.
Amy, who's aka known as the Egg Whisperer, who's a fertility doctor at Obi-G-Y-N.
We have Todd Anderson, who is a performance coach, the founder of Dream Recovery, a sleep expert.
We have Brooke Burke, who is a fitness expert, a host personality, and just overall wonderful, healthy, well, wellness person.
And we have, of course, Dr.
Abe Malkin, who is the founder of Drip Hydration, who is a concierge doctor and also a longevity expert.
So this conversation is going to be a really good one.
And thank you again for the live audience who is going to be here listening.
It's a captive audience.
And we're going to get going here.
So I'm really excited about this.
So let's start.
Oh, Mona, I'm sorry.
I didn't see you over there, Mona.
I'm sorry.
This panel is so long and
so long and vast.
I apologize.
We have Mona.
How do you pronounce your last name, Mona?
Rosine.
Rosine, who I'm so sorry about that, who's the director of scientific affairs at Chromadex, who is the parent company of TrueNiogen.
So thank you for being here.
That wasn't on purpose.
This is a very long, big panel, and please, I apologize.
Thank you for that.
Thank you for tapping me there.
That was great.
There's so many questions.
We're going to go right into it.
And actually, Mona, you're going to be my, I'm actually going to
figure it out pretty quickly, right?
Because obviously, I'm giving you the first question.
Can you please tell everybody what is NAD?
NAD is nicotinamide adenine dinucleotide.
How many of you got that right?
It's a molecule that's found in every living cell, plants and animals, and it's involved in over 500 different chemical processes in the cell.
So it's crucial, it's a crucial molecule for all cellular function and cellular performance.
Now, if our bodies lose NAD, which they do over time and exposure to metabolic stress, then if it ultimately is completely exhausted, then the cells die.
Too many cells die, then we all know what happens there, but we won't go into that.
The other aspect of NAD is that it's involved with, as I mentioned, with these
chemical processes, but it has been studied for well over 50 years.
The thing is, though, is it's been coming in growing in popularity because of the research, the celebrities that have been out there promoting it, especially with IBNAD, as well as the biohackers that are out there.
So we're finding a little bit more information about it, and the research is growing, and we're excited to see where it ends and where it evolves.
Darshan, or I know Darshan, so I can't say Dr.
Shah.
It's very weird to say that.
But Darshan, why is it so critical to our overall health?
And the other part of this is,
I think it's, it's, I want to make sure we say it at the beginning of this podcast.
Why has it become so popular as of late?
Because it's basically been around forever.
Yeah, I studied NAD when I was in medical school, which is like 30 years ago.
And we knew that everything that we do on a day-to-day basis, it all ends up as we need energy, and our cells make energy.
Our cells need energy to function.
Unfortunately, as we age and we're living longer now than we've ever had in human history, that energy level decreases over time.
And we see about a 70 to 80 percent decrease in NAD levels from the time you're 50 to 80 years old.
Without energy, your cells cannot function.
And that goes for every cell in your body.
So what I explain to my patients is, what are the benefits of NAD?
Well, it gives every cell in your body the energy it needs to do what it does best, right?
And the reason I think it's growing in popularity is because we finally have a product like triniogen that we can take that we can actually do something about this decrease in NAD that we see over our lifetime.
And
I think that, you know, most of our, people ask me all the time, who should be on NAD?
Well, anyone who has decreased energy levels in their cells.
Right.
And so maybe Dr.
Amy, because you are a fertility expert, what is the correlation then between what you do and how NAD is helpful for your patients and why you're such a big proponent for it?
Well, not to get too dramatic, as Mona said, as NAD levels decline, your cells die.
And there's one cell that I fight for every single day and I think no offense Darshan and all the guys on this panel but that's the egg cell I think it's the most important cell and you guys all have friends I imagine who've gone through fertility treatment and IVF and sometimes a woman's egg cells run out before they're done having their babies.
So that's why true niogen is really important to me in my practice.
And we also know that as NAD levels go down and it starts going down in our 30s, that's the same age that our egg supply also dwindles.
So I'm fighting for every single woman's chance to have a baby, and you know, repleting NAD is part of, it's one of the greatest tools in my tool chest that I've been using now for almost six years.
Wow, and you've seen a huge improvement with people once they start taking
an animal.
It's actually a patient of mine who introduced me to TrueNIGEN.
So she had been trying for years.
She literally had done six IVF cycles and she was a PhD scientist.
And she found a mouse study showing how if you replenish NAD mice who are NAD knockout mice, that they actually
start having babies and their fertility rates are better.
So she experimented on herself.
I did IVF on her and I was like, holy shit.
If you had not done, you guys are supposed to laugh.
I just swore.
I know it's not a Friday night, but that's okay.
And we're not drinking tequila.
It's just, you know, protein shop.
No, it's very serious of that.
I feel we're at like, yeah,
but my point was, she was 43 years old, and I said, if I didn't know you, I would have said, you're a liar.
Like, this is only the kind of cycle that an egg donor would have.
I'm like, What did you do?
And she said, I've been taking traniogen.
And I'm like, Well, then I'm gonna start taking it.
I'm gonna trick my husband to have a fourth baby, and that's what I did.
That's hilarious.
I mean, I've had actually a lot of girlfriends of mine said that when they started to, they were having problems, and then when they started taking NAD, it really they ended up getting pregnant.
I thought that was actually a myth.
It is not.
That's amazing.
His little blue pill, too, guys.
It helps us out.
Oh, wow.
Wow.
There's a lot of reasons why you should be taking it then.
Dr.
Abe, as I call you, can you tell us, please, what are some of the external stressors that happen when you have a low NAD level?
Yeah, there's a lot of factors that can cause low NAD levels in the body.
I mean, life's tough.
There's stress.
There's toxins.
People who work out a lot can burn through NAD levels quickly.
Alcohol consumption, food in your diet, which causes inflammation and causes lower NAD levels.
You know, my patients often ask me, like, how much NAD do I need?
How often should I take it?
I tell them, get as much as you can, because everything you're doing in your daily life is causing you to burn through your NAD levels.
And you really can never have too much NAD in your body because you're going to go through it.
You know, it's like getting an oil change.
Like, you can never have too many oil changes on your car.
It's just going to make your car operate better.
And so I try to give people that sense that as much NAD as you can get into your body, whether it's a daily pill like true niogen or other forms of NAD, can only be beneficial in the long run.
So actually, Brooke, so then how does it help you?
Because you work out a lot, you live a very healthy lifestyle.
How do you integrate it into your life?
What do you do?
It's a long list for me.
I mean, the bottom, I'm going to try to humanize this too, because I know this is a lot of science and it can be overwhelming and confusing for everyone.
For me, increased levels of NAD feels really, really good.
And I've actually been a consumer before I was a partner.
So just to bring some authenticity to this, Rob Freed turned me on to to true niogen about seven years ago.
I've been taking it ever since, and my claims could go on and on, but we have a lot of rules and regulations.
So I want to say that I am always striving.
I'm a bit of a bio-hacking geek, but I'm always striving for mobility, longevity, energy.
Feel good.
I'm trying to manage the very demanding, chaotic challenges in my life.
I take it every day.
It's a supplement for my cells.
Every single day.
My friends take it, my family take it.
No bullshit here, honest to God.
I take it every day.
Sometimes more than one, sometimes more than two.
But it just, it feels good.
And I know that it's helping me combat stress.
I know that it's helping me on a cellular level.
And I know that we're all trying to up our wellness game.
And there's so many different things that are available to us.
I'm a big believer in NAD.
And we can get it in a variety of ways that aren't as easily accessible to everyone.
Truniogen has made it really simple.
I look at it as a daily supplement for my cells.
And I think that's...
really fair to say.
And sometimes I double it up when I have more stress in my life and life is happening.
So we could go into the science of it and I know that we will, but it's your daily, it's your daily supplement.
And that's, you know.
I'm with you.
So like, I mean, we have a very similar lifestyle, and that's why
I'm a huge believer in triniogen.
I've been taking it, what, for the same, like six years, a long time.
And people always ask me, like, oh, how do you feel?
I don't necessarily feel differently because, you know, when you, when you do something for so long, that becomes your new normal.
You don't know the difference, right?
But I do know that it's everything's, thank God, things are all in the same place still since it was, you know, before I took it and I've aged.
But I think it's been like an amazing asset for my overall routine and regimen.
And Todd, you're a performance coach.
How have you found it to be, let's humanize it a little more.
I like that.
How has it helped and how has it benefited you?
Talk about your background, how you've used it, and why it's been so significant in your life.
Yeah, so I come from the athletic world and I still work with, you know, professional athletes or Olympians on the sleep side, but also on the performance side.
So I think for myself and a lot of the athletes we work with, the biggest thing is just, you know, there's just such massive demands from a metabolic perspective, energy perspective, across the span of a week of a hard training cycle.
And a lot of times, like, you'll see a decrease in performance over that week, right?
So I think the biggest thing is just...
sustained performance and you know that Saturday workout they're able to come to the same intensity as that Monday workout
And feeling a pretty significant difference between the two, like prior, you almost feel that tail off.
And the other thing I think, because they're able to increase that workload, you know, and feel better and perform at a high level consistently, even, you know, from a body composition perspective, because of that increased workload, you know, we'll see decreases in body fat percentage.
Obviously, especially for the swimmers we work with, having lean mass and being as light as possible and as strong as possible is very beneficial.
So we've seen that in a result just because they're able to do more consistently.
Okay, so how do we, someone can answer this question.
We can go to Darshan, one of the doctors here.
How is it possible to increase our NAD levels just without taking a supplement?
Are there actual ways naturally to boost our NAD?
Yeah, so everything that you can do to improve your health routine is going to improve your NAD levels.
So when people ask me this question, they say high-intensity intermittent training is good, making sure your nutrition is on point, avoiding processed foods.
A lot of it is about what you don't do as well, like not exposing the body.
Talk about that.
Talk about the things that are, yeah.
You know, we live in the most toxic environment that humans have ever been exposed to.
Not here in Malibu at your home, Brooke, but just in general, humanity is.
And just keeping yourself away from toxins as much as possible.
You know, making sure your water is filtered or reverse osmosis, air purifiers, making sure your food is organic, staying away from ultra-processed food.
Staying away from these type of things is going to boost your NAD levels naturally, allow your body to catch up, right?
Right.
And then from there,
you still need an additional boost, and that's why we have these supplements that you can take.
Right, right, right, right.
So, then a lot of these external environmental factors can really help, really deplete your NAD naturally.
Exactly.
Wow.
Okay, let's talk a little bit about.
I'm curious, and I think this is what the big question I'm seeing all the time online on social media.
Like, there's a huge controversy between NR, which is, of course, what we're talking about, and NMN.
Who can talk about this issue?
What is the difference?
What are they?
This is the gold right here.
Who wants to take it?
Anybody?
I can take that one.
So, chemically, and from a structural perspective, NMN has a phosphate attached to it.
And with that phosphate, it makes the molecule too big to cross the cell membrane.
And so, what happens outside of the cell, so say for instance, you're supplementing with NMN, your body has to break that down, and ironically, it actually is broken down into NR.
And then NR can cross the cell membrane.
And once it gets inside the cell, then it's converted into NAD within just two short enzymatic steps.
So that's one of the primary structural differences between NMN and NR.
The other unique difference is that if you compare the two, NR versus NMN, there's about a 25%
efficiency perspective of NR being able to raise NAD.
So NR can raise NAD by 25% more than NMN can.
The other aspect, because of that phosphate that I had mentioned, it weighs more.
So from a molecular weight perspective, you need about 15% more NMN to be equal to the same amount of NR, like if you wanted to shoot for 300.
Now, the other aspect that we have just found out about a year ago is that the FDA came out with a statement prohibiting NMN to be used in supplements.
So technically, it's illegal for, in the U.S.
for supplement companies to sell NMN based on FDA's decision.
So that's the primary differences of NMN versus NR.
Yeah.
I want to talk a little bit of why I'm such a big fan of TrueNiogen because there's a lot of kind of like Me Too brands out there of doing claiming the same things.
And I think it's really important to put some notice on the fact that because of the data, the research, the science behind it, that is why it is the gold standard in NAD.
Can we just talk about what as a company, what we do that is so much more above and beyond what anybody else is doing out there?
Because I think that's really important because especially with social media, people don't know what they don't know.
And
I think
these are the factoids that people have to know to have a distinction between a brand that's exceptional and a brand that's like below average.
So with TrueNIogen, quality is in our DNA.
And we do over 22 different tests, internal and external third-party tests, for quality, for safety, and for purity on niogen, which is the active ingredient found in true niogen.
The other aspect, from a science perspective, is that we have an external research program called CERP, Chromadex External Research Program.
And with CERP and through CERP, we have collaborated with over 275 different research organizations globally.
And what we do with that research program is that we provide material.
So we provide placebo as well as active truniogen for the studies that these researchers apply.
in our program.
The other aspect of that is that of those studies, 95% of them are third party.
So even though we provide the material, we don't get a say in what the methods are going to be.
So it's not industry driven or it's not chromedics driven or truniogen driven and we want the researchers to study this.
They come to us with a proposal, we provide the material, and that's about it.
And we have that agreement there.
The other aspect that that CERT program has resulted in is over 25 human clinical published studies.
So, and then we also have two Nobel
Prize winners who back TrueNiogen.
Does that mean most other, I mean, you don't know, you don't, but it's just above and beyond, just based on the, like, is there a standard of research or data or science that people have to be held to, or is it kind of like the wild, wild west out there?
Well, overall.
Yeah, unfortunately, the supplement industry has been deemed the wild west, and that's just because there's not a lot of companies who do the type of research that we do that back up their ingredients that they have or their ingredient.
The other aspect, going back to NMN a little bit, is that a few years ago, Chromodex did an analysis of over 20 different NMN products that were on the market, and almost two-thirds of those products did not have or meet label claim.
So it's
so we have to be careful, you have to be cautious, and there are different things that you need to look for on labels when it comes to how do you find that quality.
The other aspect, too, is when you know the maker and you know that they are the ones that are doing and creating the ingredient, then you trust them and you build that trust and that credibility behind it.
Yeah, I mean, I think it's really important to know because, again, you don't know what you don't know, and people's
marketing can usually dominate what people's choices are.
And a lot of times, it's just the marketing.
Okay, this goes back to maybe Dr.
Abe, would you mind answering this question?
How do people know, right?
I mean, yes, based on our healthy or health habits or lack thereof or our age or whatever the reason or that, how else can you tell if a patient is deficient in NAD?
Are there signs, like physical signs that you can you speak to?
I think it all goes back to the nature of what NAD does in the body, driving cellular energy production.
People that are deficient in NAD, like all of us, after the age of 30, as your NAD levels start to decline, you start to exhibit signs of aging,
fatigue,
workouts aren't as good, difficulties with cognition, memory, focus, things like that.
That is all the aging process.
And
as a
longevity specialist, the goal for my patients is how do I age more gracefully?
How do I reverse the clock on the effects of aging?
At its very core,
energy production is really what makes you feel youthful.
And as you age, that starts to decline.
And so people are always looking for a silver bullet of how they can turn back the clock.
And thankfully, we have NAD in various different forms.
And the pill form is the most easily digestible for patients to do on a regular basis as the bedrock for their anti-aging regimen.
So this has been tremendously beneficial for patients.
the benefits are so wide-ranging that almost anyone can benefit once they start reaching the age where their NAD levels decline.
Can I just add to that too?
Because I was going to say that I think we would all agree that there's not like a magic pill.
And I like to think about manipulating the system, but it's not really cheating the system.
We're trying to fuel our system.
And correct me if I'm wrong, but on around 30, our NAD levels drop, and then the next day they drop again, and the next day they drop again, and so on and so forth.
So as time goes on, when we start to feel the effects of aging, we recover slower, we repair slower, our energy drops.
I've just found that as a regular user, I'm able to increase those characteristics in my own life.
And that's been a real game changer for me.
And it is hard, like Jen said, to differentiate because we do so many things to up our wellness game.
It's really hard to know what's doing what.
But I definitely feel those things, and I'm striving for those things on a daily basis.
And we need to improve our NAD levels for sure.
Which that's a great segue into what I wanted to ask maybe Dr.
Amy or Dar Sean.
Is there an age that people should start taking it at?
Like to be prevented?
Is there a preventative piece to this or an age?
What do you, either one of you guys can?
I mean, for my patients, if they're taking it as a fertility patient, they actually love how it makes them feel.
And they want to take it even after they deliver.
At what age is of age?
I mean, they can be 32 years old and want to be on it.
They can be 25.
Because I get a lot of questions from people who are in their 20s.
Like, oh, should I start taking it?
Like, athletes, a lot of athletes ask me when they're like 23, 24, you know, should I start taking it?
Will it help my recovery?
Will it do this?
And
I want one of the
professional doctors here to say if there is an age,
is 19 too young?
Like, is there an age that's too young to take it?
I think for me, it just depends on your clinical history.
Yeah, it's really patient-dependent.
And so, you know, I see a lot of people that are just even post-adolescent that have like insulin resistance.
And they would benefit from NAD.
I think athletes that are working out hard, you know, five, six days a week in the gym, they should be on NAD.
Really, you know, you start making NAD from the moment that you're conceived.
So you start getting depleted the moment you're born.
Like really, like at two months, you're going to give it to a baby that you deliver.
No, we're not going to give it to babies.
Maybe two.
But technically you can, right?
There's no.
You're not going to OD on NAD.
I give it to my daughter who's 22 years old.
Well, honestly.
Oh, you do?
When she's run down, when she's under the weather, when I know her life is stressed out, managing what a young woman has to, and she communicates with me that she feels better.
I won't go on the record and say that we can claim that, but I will tell you that you're not going to OD on NAD.
You got to let your body be your guide.
Listen to your body as we become detectives, you know?
Absolutely.
Hey, Todd, you're up.
So
what is the connection?
Is there any kind of connection between sleep and NAD?
Is there any kind of
resource that you can talk about?
We talk about the silver bullet.
Sleep, it's hard to argue.
That's probably the closest thing to a silver bullet.
But I think from a cellular energy perspective, when you align those two things and support NAD, especially with supplementation, I mean, it's one of those things, especially in the athletic world, we always talk about like, you don't want to leave anything on the table, right?
Like, what if there was that 2% or 3%?
And you talk about what age you should start at, but you don't want to leave anything on the table.
I think we don't either as day-to-day human beings.
Like, we want to feel as good as we possibly can because we're going to do the most we can when we're feeling the best, right?
So it's one of those things you might as well do it and top it off and make sure your levels are the place you want to be and you're feeling great.
And the combination of sleep and the supplementation, I mean, it's hard to beat that.
And I think from an athlete perspective, also, we haven't talked about this, but the quality of ingredients and being NSF certified, so that's the first thing we look at for athletes.
If it's not an NSF-certified supplement, they're not going to touch it because you're responsible for that going to your body.
Can you tell us what NSF is?
Just safe sports certified.
It's a third-party testing organization that says, look.
In English, please, Todd.
I was getting there, Jenny.
Okay.
This has been my whole weekend.
But
basically, what's on the bottle is in the bottle.
That's what it's saying, right?
And that's very important for athletes.
And then from an IV perspective, they don't have a lot of time.
It's uncomfortable, right?
And that's not something they're probably willing to do.
And if it's more effective to just take a supplement, you know, oral supplement, that's a lot better.
The other thing is with Olympic sports, USADA, WADA, you cannot get an IV over 50 milligrams without a TUE, a therapeutic use exemption.
So instead of going through that process, if we know something is more effective, it's much easier just to, you know, supplement using true niogen.
Right.
Good answer.
I think also one, sorry, Jen, if I could jump in.
One other cohort of people we haven't talked much about is people with addiction problems.
You know, we all drink and alcohol is such a big part of our lives.
You know,
some of us or some people we know may have addiction problems.
And if there's one thing you can do to help them, if they're not willing to stop drinking, it's take NAD because they're burning through their NAD levels probably faster than all of us.
So in the addiction space, NAD has been very helpful for patients struggling with addiction, trying to feel normal and trying to regulate their body while they're being exposed to so much toxin.
I was actually going to ask you about that because you and I have talked about this a lot
offline here.
Isn't it also what people do when they're in rehab, like for rehabbing addiction?
I mean,
I don't know if this is allowed to be talked about in terms of the
legalities, but I know that
you use this a lot for your patients.
Can you talk about that?
Yeah.
Addiction and detox is a big part of my practice in addition to longevity.
And for those patients, you can imagine they are burning through their NAD way faster than all of us.
Maybe not the Olympians, but way faster than people who are living their normal lives.
Why is that?
Can you talk?
I'm curious.
Yeah, the toxins in their body essentially destroy the cellular energy that they're producing and make cells less efficient, makes their NAD production lower than what an average person would have.
And so they feel fatigued all the time, irritable, brain fog, and that's often a result of poor NAD levels.
So in that patient cohort, NAD supplementation is incredibly beneficial.
How much do you need to supplement?
Like what is the amount?
Yeah, I mean, Todd mentioned it.
You know, some people need IV NAD on a regular basis, especially during detox.
could be multiple times a week, but that's not accessible for everyone.
So certainly a daily NAD supplement is really the bedrock foundation.
And then beyond that, whatever patients can manage is beneficial.
Because I know TrueNiogen, they have lots of different dosages, right?
300, I know the other ones, 500 that I've been taking is more professional, the more
prescribed.
Is there any other type of dosages, Mona, that
you want to talk about or we can any product lines that may be?
Well, the True Niagin immune, which is also up there, has 150 milligrams of niogen in it.
So there's technically three different doses.
So 150 in the immune, 300 milligrams, which is kind of standard consumer one, and then 500 milligrams, which was our exclusive to HCP healthcare providers.
So what people
will need per se is very individualized, and usually the healthcare provider will prescribe what is the most taken.
Now,
for those of us who just take it, like for me, I take anywhere from 300 to up to 1,500 milligrams, depends on what's going on.
Oh, wow.
Clearly I'm not healthy right now as you guys can see.
Well you might be healthy.
You just have something broken or sprained.
What is it over there?
What do you mean?
I have a rotator cup.
I have a tendon that's healing.
Oh wow.
You got to up your NAD I guess then.
So Dr.
Amy, do you start your patients on a lower dose and then you graduate?
Is it more of a gradual thing or how do you kind of decide what someone's baseline they start at?
I do.
So they also have these powder packs that have patients also get so they can start off really slow so they they can even take like half of that pack and then they see how they feel and they slowly go up.
And my patients, as you can imagine with the things that they've been through, a lot of them have a lot of anxiety.
And so sometimes when you start off really high all at once, you feel like you're, you know, you just feel kind of...
amped up.
And so that sometimes can cause people to feel a little distressed, like there's something wrong with them and really isn't.
So they start low, they slowly go up.
Once they can tolerate 150, then we go up to 300.
Once they can tolerate 300, then we add a 150.
And then now more recently, some of my patients have been going to 500.
I think the powder sticks are a great option as well to put into smoothies.
Some people even put them in their coffee.
They're really easy.
They don't have a flavor, so it's a great addition in there.
And then you're getting that.
I do both of them.
I do a lot of them.
You do that?
Okay, what are your daily habits, bro?
It sounds like you do a lot of things.
How much time do we have?
I do everything.
I'm chasing the feel-good.
Okay, so in addition to, and I'm very, very skeptical about things that I take in the supplement world, I try to get everything that I can naturally.
I try to eat the colors of the rainbow, mostly plant-based.
I do eat meat.
But in addition to the true niogen, I mean, I'll do fire and ice, infrared saunas.
Trust me, the cold plunge, really difficult.
I understand the benefits.
Goal on my list.
I'm not doing it daily.
But I also move my body.
I exercise regularly.
I do it for my knees, for my back, for longevity, for mobility.
I do it for community connection.
I believe in all of the things that I think we're chasing right now for longevity.
For me, it starts from within.
So I'm very, very mindful of what I put into my body.
Then I'm mindful of how I treat my body, how I speak to my body.
I'm a big believer in meditation for clarity to elevate my mood.
I'm a big believer in positive, loving, inner dialogue and body confidence, raising children, raising young women.
It's a long list, but I do want to say this to everybody.
It's a daily practice, and people think that self-care comes easy.
It doesn't.
This is a commitment.
It's a daily practice.
We have to continue to elevate.
We have to educate ourselves.
Even days like this, this is a playground for self-care.
It's super fun.
You're all going to go home with great swag bags.
We get to meet new friends.
We're networking.
But we also come to learn and we come to share stories and we come to educate people.
And trust me, besides being a consumer, this is really hard to digest for us, to understand what all of these big names and terms mean.
But I think when you trust a brand that you've done your research on and you make it a daily practice, you start to feel the benefits, right?
And then you continue.
And the better that we feel, the more we want to do.
The more we do, the better we feel.
It's like exercise.
We don't all love it.
The more you exercise, the better you feel.
The better you feel, the more you want to work out.
So I do a lot of stuff, but my basic needs are what I put into my body, how I speak to my body, how I treat my body, and how I move, right?
And how I connect in the world with people like you.
So we're going to get a little bit of that over there when we're done.
Right, we're going to do that later.
But I'm obsessed with habits, of course, it's my podcast, Habits and Hustle.
I always ask everybody what they do because that's how you up-level your own game, right?
You can always just find maybe even a nugget of something that you didn't know.
And it's, I think, anything and everything is about consistency.
If you do anything just one time or two times, you're not going to see any benefit.
That's for exercise, that's for meditation, that's for supplementation, for anything.
Anything you do, you have to do it consistently to have any type of benefit.
Todd, knowing that you're here as well and you're obviously a sleep expert, you obviously exercise a lot.
So I want want to know what your habits are.
Like, how are you so fit?
What is your daily regimen?
I don't know about that, but
I'm a non-negotiable cold punch person, which is
non-negotiable.
You don't do it every day, so I'm judging you.
It's the first time I met you, so it's a tough, tough first impression.
Three minutes.
But I mean, the cold punch I do.
Every day, three minutes?
It is horrible for everybody.
Some people are like, I could never do that.
Like, every person that does it, it's like, it thinks it's the same thing.
It's like not fun.
No, it's horrible.
But I think there's something to that.
Oh, but wait a second.
Let me just say this, okay?
Because I know Todd and his whole house is a playground of saunas and cold plunges.
He literally has like 11 in his backyard.
We have like a sauna guest book with a Polaroid and people sign in.
It's pretty elaborate.
It's crazy.
So
you do that every single day, sauna, cold plunge?
Oh, definitely, yeah.
Usually have like a group of 30?
At least 10 over, yeah.
Honestly, though, the community, when you combine the sauna, you know, you get a little dopamine, no phones in the sauna.
It's rare in this day and age to have the community that you're facing each other in a little adversity.
Like, you can develop some friendships fast.
100%.
That's why it's taken me and Jen a little longer.
We haven't been in the sauna.
Exactly.
She's still cutting me off and working on it.
Yeah, exactly.
It's taken a little longer than normal.
I'm sorry.
Yes, it's true.
And then, like, I mean, I'm obviously adamant about my sleep.
My bedtime at wake-up time is nearly perfect most of the time, depending on travel.
But yeah, and then mouth tape, obviously.
Mouth tape, right?
Mouth tape is a big one.
temperature yep and then how about so you work out daily though as well right strength training yeah test all yeah how about the fact that I think we said this earlier that so strength training helps naturally build NAD levels correct right and that's not that's not how much does it build it how much does it increase by no I'm asking well you or a doctor Dr.
Abe how much does it increase if you strength train your NAD levels well muscle in general is a very important part of health because muscle is an anti-inflammatory type of tissue as opposed to fat or other types of tissues that are pro-inflammatory.
So it's not just about NAD.
Building muscle in general helps with anti-aging, which is actually why strength training in addition to cardio metabolic exercise is also important, especially as you get older.
So after the age of 35, 40, building in strength training as part of your routine is incredibly important.
It will lower your inflammation, reduce oxidative stress on your cells and the rest of your body, help maintain NAD levels in addition to a whole host of other benefits.
Darshan, you're like the longevity king over there, too.
So, can you tell us, I want to know your daily habits and things that you recommend for people in an overall holistic way to kind of try to incorporate into their daily regimen?
Yeah, so a lot of the things that we talk about here, big sauna, Coldplan fan, of course.
I have one.
You have every day?
Every day.
Every day that I'm traveling.
Yeah.
I have one in my house.
Okay.
Yep.
Of course you you do, right?
Yeah.
And the sauna, incredible for sleep.
I do that before nighttime as well.
But I think a couple of things that have not been mentioned that I like to incorporate as well is I try to get a breath work practice in at least three or four times a day.
I think that's really important for managing cortisol levels.
Cortisol is another one of those hormones in our body that really cause a lot of bad things to happen.
And keeping your cortisol levels under control is a massive benefit.
So interrupting that cortisol cycle with things like a breath work practice is super important as well.
And another thing that I do that I've kind of got my kids to do now too is before I touch anything that's electronic in any way, I go completely analog and I read every morning for about 30 minutes.
And that really is more,
it's not just a knowledge that you're gaining, but it's also the mindset that you create first thing in the morning.
So you don't go onto your phone for the first 30 minutes?
Yeah, I keep on my phone in a different room that I don't even go into until after I've done my morning routine.
Wow.
So how how long is your morning routine?
It's about an hour and 10 minutes or so.
I mean, some of these morning routines, guys, I think it's, I mean, I talk about this at Nauseum on my podcast.
Like, some of these people's morning routines are like four hours.
It's like dinner time by the time they finish their morning routine.
It is crazy.
They don't have jobs.
What?
They don't have jobs.
People don't work anymore.
I feel like you work in between the morning routine.
Like, you know, you have a few minutes like sprint that you'll maybe like check an email and go back into the sauna or go back into the cold plunge or go to the gym.
I mean, the gyms are packed here in L.A.
at like 2 o'clock in the afternoon.
It's so crazy.
Welcome to LA.
So, Brooke, I want to ask you, actually, is there any exciting launch or new addition to the true niogen family that you want to talk about?
Well, I want to talk about all of it, but are we privileged to do that?
Are we talking the true niogen immune or are we announcing?
I don't...
I'm getting yeses or no's.
I think.
Am I the one that's going to get in trouble?
Yes, we are good to go.
I mean, I already bringing it up.
Do we have a bottle?
Do we have the beautiful new shiny silver-ish bottle with the new secret milligram dose on it?
Okay, correct me if I'm wrong because I wasn't totally prepared for this, but I think it is.
So, somebody like me, I usually double-dose, sometimes I triple-dose.
I'll be honest, sometimes even more, depending on what my body is asking.
I really have learned to be a detective.
I let my body guide me for my personal needs.
So, now we are launching a new dose that is going to simplify that for everybody, especially especially those that don't like to take a handful of pills.
And I think it's coming.
And we're going to meet him, her, it
right now.
Awesome.
Well, this is good.
You've been holding out on all of us.
Okay.
Pro, 1,000 milligram.
We are all really, really excited about this.
And we've been waiting for this dose because this is going to eliminate having to take multiple pills.
So that doesn't mean that I get to probably double up anymore, but this is going to be a game changer for everyone.
And we have been waiting on this.
This is the clinical strength.
Prior to this one was the TrueNiogen Immune that has very high integrity ingredients.
And we can all chime into this too, but I think it was DC.
Maybe cucuramin was in that one as well.
And it used to be during COVID that there was sort of a handful of supplements that I think many of us were taking to combat stress.
When they launched the TrueNiogen Immune, it was sort of all in one.
Incredible research also behind the quality of all those ingredients.
So this is the new baby, everyone.
1000.
Have you seen this yet?
1,000 milligrams.
This is the only one, so I'm keeping it.
And I don't know what we're all going home with, but we're really excited about this one.
Does anybody else want to add to this?
Because you may have more clinical information than I'm not.
Am I doing it justice?
Well, one of the other aspects about the 1,000 is that that dose at 1,000 milligrams is where the majority of the clinical studies have used for that.
So over half of our clinical studies are using 1,000 milligrams, and there's also another percentage, not quite the other half, but about the other third is 2,000 milligrams.
So, we do know it's safe up to 2,000 milligrams, and that's one of the main reasons we're excited about that one.
And I also just want to read the tagline that finally it says advance inner body aging science.
So, again, like it's all about what starts from within.
Wait, I have one more question.
By the way, I forgot one thing.
Do you mind if I ask one more question from Etmona, Darshan, whoever on this side of the panel?
This is the longest panel, by the way, I have ever done.
I was going to ask you, do we get acclimated to what, let's say we're taking a 300 milligram, does your body get acclimated where you have to kind of move up to see any kind of difference?
Yeah, I think once you start taking a lower dose and you get used to it, I always try to push my patients into the 1,000 milligram range, actually, is where I think the ideal dosing really is.
So, like, you know, you were saying, we start off slow, but I'm always trying to get them to 1,000.
Right, because in anything else, like, your body acclimates acclimates to anything you take for a long time, right?
So, the thing that we've seen in the studies is that it'll raise your NAD to a certain percentage, so say on the 300.
It raises up about 50 percent higher than what your baseline is, and then it holds it there.
The study that I'm referencing was eight weeks long, so you'll hold it at 300 milligrams at about 50 percent more than what your baseline is.
The unique thing about a thousand is that it goes up to 150 percent from your baseline, and then again it holds it there over the eight weeks that the study was done.
So, it it acclimates, but it also is very dynamic.
As we know, NAD is extremely dynamic, so it depends on consumption and production and how old you are.
Because the older you are, then your production does not keep up with the consumption because the external metabolic stressors that we're exposed to all the time could increase how much is being consumed.
And so the benefit of the thousand is that one, we can take a heck of a lot less capsule so we don't get pill fatigue and then maintain it at a higher level.
The baseline, yeah, like if you're you're on a thousand milligrams, then you'll you'll maintain right around that 150% more than your baseline.
That's what we're seeing.
Is there anybody or any population of the people who should not be taking NAD, Abe?
Virtually all patients can take NAD safely.
It's something that's naturally occurring in your body.
I will say that patients who have active cancer, I work in conjunction with their oncologists to make sure that they are okay with that as part of their treatment plan.
Not to say that it's not safe, but I think it has to be taken into consideration as opposed to an overall treatment plan.
I'm so glad that you just, again, this is, I'm glad that you mentioned that because some of the questions, you hit on a couple, the rehab detox part, I get that all the time for that as a benefit.
The other one is for cancer because
your cells are turning over quickly.
So there,
I mean, I would like you to expand or somebody to expand on that whole thing with cancer, cells.
Yeah, I mean, NAD is a naturally occurring element in your body, so it's not as though you're giving your body something it's not already producing.
You know, cancer cancer is a proliferation of cells.
There's no reason to necessarily think that NAD will cause the proliferation of cancer cells, but again, I think that it has to be taken into account with the other treatments a patient's taking.
So we don't put patients on it without consultation with their oncology providers.
Jen, I think it's important for people to know, too, as just a daily maintenance program.
The stressors of life, immune stress, our NAD levels can drop.
I think it's 80%.
You know, our studies have shown that.
So in listening to your body, it's important to, I think, increase your dosage of true niogen when you're going through those tough times, lack of sleep, stress, sickness, life, love, business, whatever's bringing you down.
Really learning how to listen to your body.
And I don't think there's really too much personally, but letting your body be your guide and knowing how to biohack, if you will, and manipulate your own system.
Well, we look like you if we take NAD.
Yes, yes.
Yes, perfect.
Sold, right there.
amazing okay so that I think we're I think we're good to go I think we've kind of answered every question I want to say thank you a big thank you to my very big panel of experts here I appreciate your knowledge your expertise for joining us on this conversation today we have a lot of other fun-filled wellness things we're going to be doing Brooke I think you're going to be doing a workout right now right I am and I think I'm correct that about 130 we're going to meet on the lawn and don't be worried we're not going to do a really intense body sculpting cardio class.
We're going to get mindful.
We're going to slow down.
We're going to try to get really present out here and connected in Mother Nature.
We'll do a flow.
We'll do some breathing.
We'll do some stretching.
I'll guide the class to everyone's abilities.
So no intimidation.
It's a very safe, free space.
And I think you'll really enjoy taking your shoes off, being on earth, being in the trees, Mother Nature, vitamin D.
It really will change you.
And there's so many wonderful little pop-ups everywhere.
So take about a half an hour, mingle, get to know each other.
Find any of us, by the way, if you have any further questions.
But experience everything from the drinks to the experiences that are set up.
You may not have wandered over there.
The Manifest Company is super cool.
One of my favorites.
You can design your own yoga mats.
There's shots.
There's the cold plunge.
Right.
Actually, it's called the Therafrost.
It's a non-negotiable cold plunge before anyone gets a goodie bag.
You should go first.
I'll go.
I would do it with you.
That's true.
Actually, in that area, it's called the Therafrost by Therisage.
They also have a portable sauna.
So you can try the hot cold.
Yeah, so you can try the hot cold, which is what I think Todd was mentioning earlier, right?
You were talking about fire and ice, or Brooke was saying it too.
Yeah, she was saying how she's scared to go in the cold punch some days.
Yeah, and I'm with her on that.
And
I definitely recommend giving it a shot if you haven't done it.
And by the way, I want to say if any, also people listening, because this will eventually get on Habits and Hustle.
If you guys need any more information on TrueNiagen, you can go to Truniogen.com where there's a list of all their fantastic products.
And, or, like I said, and if you have any other information,
you can contact me.
You can find Brooke, Furke, Todd Anderson, Dr.
Darshan Shah, Dr.
Amy, Mona, I'm not going to forget about you this time, or Dr.
A.
Malkin on social media.
And thank you very much for listening and have a good one.
Bye.
Thank you, John.
Thank you.
Thank you, everyone.